Detailed information    

insolico Bioinformatically predicted

Overview

Name   codY   Type   Regulator
Locus tag   I6L86_RS06365 Genome accession   NZ_CP077259
Coordinates   1319363..1320151 (+) Length   262 a.a.
NCBI ID   WP_000940738.1    Uniprot ID   A0A2I1UDY5
Organism   Streptococcus mitis strain FDAARGOS 1456     
Function   repress the expression of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1314363..1325151
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6L86_RS06350 (I6L86_06350) murT 1314453..1315796 (-) 1344 WP_000770028.1 lipid II isoglutaminyl synthase subunit MurT -
  I6L86_RS06355 (I6L86_06355) - 1315895..1317211 (-) 1317 WP_000958913.1 FAD-containing oxidoreductase -
  I6L86_RS06360 (I6L86_06360) - 1317541..1319106 (+) 1566 WP_000671119.1 DEAD/DEAH box helicase -
  I6L86_RS06365 (I6L86_06365) codY 1319363..1320151 (+) 789 WP_000940738.1 GTP-sensing pleiotropic transcriptional regulator CodY Regulator
  I6L86_RS06370 (I6L86_06370) - 1320151..1320726 (+) 576 WP_000158729.1 cysteine hydrolase family protein -
  I6L86_RS06380 (I6L86_06380) - 1321031..1322308 (+) 1278 WP_001068275.1 ABC transporter permease -
  I6L86_RS06385 (I6L86_06385) vex2 1322321..1322968 (+) 648 WP_000173751.1 ABC transporter ATP-binding subunit Vex2 -
  I6L86_RS06390 (I6L86_06390) vex3 1323024..1324403 (+) 1380 WP_000902997.1 ABC transporter permease subunit Vex3 -

Sequence

Protein


Download         Length: 262 a.a.        Molecular weight: 29676.00 Da        Isoelectric Point: 5.2441

>NTDB_id=506045 I6L86_RS06365 WP_000940738.1 1319363..1320151(+) (codY) [Streptococcus mitis strain FDAARGOS 1456]
MAHLLEKTRKITSILKRSEEQLQEELPYNAITRQLADIIDCNACIVNSKGRLLGYFMRYKTNTDRVEQFFQTKIFPDDYI
QGANMIYDTEANLTVDHDLSIFPVESRADFPDGLTTIAPIHVSGIRLGSLIIWRNDKKFEDEDLILVEIASTVVGIQLLN
FQREEDEKNIRRRTAVTMAVNTLSYSELRAVSAILGELNGNEGQLTASVIADRIGITRSVIVNALRKLESAGIIESRSLG
MKGTYLKVLISDIFEEVKKRDY

Nucleotide


Download         Length: 789 bp        

>NTDB_id=506045 I6L86_RS06365 WP_000940738.1 1319363..1320151(+) (codY) [Streptococcus mitis strain FDAARGOS 1456]
ATGGCACATTTATTAGAAAAAACTAGAAAAATTACTTCTATCCTGAAGCGCTCAGAGGAGCAGTTGCAGGAAGAACTTCC
CTACAATGCGATTACCCGTCAATTGGCAGATATTATTGACTGTAACGCCTGTATCGTCAATAGCAAGGGACGTCTCCTTG
GTTATTTTATGCGTTACAAAACCAATACAGATCGTGTAGAGCAGTTCTTCCAAACTAAGATTTTCCCAGATGACTACATT
CAAGGTGCGAACATGATTTACGATACAGAAGCCAATCTGACAGTTGATCATGATTTAAGCATTTTTCCTGTGGAAAGTCG
TGCCGACTTTCCAGATGGTTTGACGACTATTGCACCGATTCATGTATCAGGGATTCGACTTGGTTCTTTGATTATTTGGC
GCAATGATAAAAAATTCGAAGACGAGGACTTGATTCTTGTTGAGATTGCGAGTACCGTTGTTGGAATTCAACTCCTTAAT
TTCCAGCGTGAAGAAGATGAGAAAAATATCCGTCGCCGTACTGCTGTTACCATGGCGGTTAATACCCTTTCTTACTCCGA
ACTCCGTGCTGTTTCAGCAATTTTAGGGGAATTAAATGGAAATGAAGGGCAGTTGACTGCGTCTGTGATTGCAGACCGTA
TCGGAATCACTCGTTCTGTGATTGTCAATGCCCTTCGTAAACTTGAGTCTGCAGGGATTATTGAAAGTCGCTCACTTGGA
ATGAAGGGAACCTACCTTAAGGTTTTGATTTCAGATATTTTTGAAGAAGTGAAGAAAAGAGATTACTAA

Domains

Predicted by InterProScan.

CodY helix-turn-helix domain (HTH_CodY)

(202-258)

CodY GAF-like domain (CodY)

(3-182)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2I1UDY5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  codY Lactococcus lactis subsp. lactis strain DGCC12653

62.595

100

0.626
  codY Bacillus subtilis subsp. subtilis str. 168

48.78

93.893

0.458