Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB2   Type   Machinery gene
Locus tag   HPPC18_RS04960 Genome accession   NC_017742
Coordinates   1060820..1061104 (-) Length   94 a.a.
NCBI ID   WP_000413637.1    Uniprot ID   A0AB72ZV75
Organism   Helicobacter pylori PeCan18     
Function   transformation-associated type IV transport system (predicted from homology)   
DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
IScluster/Tn 1061227..1062814 1060820..1061104 flank 123


Gene organization within MGE regions


Location: 1060820..1062814
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HPPC18_RS04960 (HPPC18_05025) comB2 1060820..1061104 (-) 285 WP_000413637.1 TrbC/VirB2 family protein Machinery gene
  HPPC18_RS04965 (HPPC18_05030) - 1061227..1062378 (-) 1152 WP_000909425.1 RNA-guided endonuclease InsQ/TnpB family protein -
  HPPC18_RS04970 (HPPC18_05035) tnpA 1062347..1062814 (-) 468 WP_000063681.1 IS200/IS605-like element ISHp608 family transposase -

Sequence

Protein


Download         Length: 94 a.a.        Molecular weight: 10753.05 Da        Isoelectric Point: 10.7837

>NTDB_id=50565 HPPC18_RS04960 WP_000413637.1 1060820..1061104(-) (comB2) [Helicobacter pylori PeCan18]
MEKLRHFRKLIAFLGFSPLLLQADMTTFFNSIEQQLTSPTAKGILMVIFLGLAIFIWKNLDRWKEILMTVLAIAIGAAIF
FKAPALANWFMSIF

Nucleotide


Download         Length: 285 bp        

>NTDB_id=50565 HPPC18_RS04960 WP_000413637.1 1060820..1061104(-) (comB2) [Helicobacter pylori PeCan18]
ATGGAAAAATTAAGGCATTTTAGAAAGCTTATCGCCTTTTTAGGTTTTTCACCTCTTTTATTACAAGCGGATATGACTAC
CTTTTTTAATTCCATTGAACAACAGCTCACTAGCCCTACGGCTAAAGGCATTTTAATGGTTATTTTTTTAGGACTTGCTA
TTTTTATATGGAAAAACTTAGATAGATGGAAAGAAATTTTAATGACCGTGCTTGCTATTGCAATTGGTGCTGCAATCTTT
TTTAAAGCCCCAGCCTTAGCTAACTGGTTTATGAGTATTTTTTAA

Domains

Predicted by InterproScan.

TrbC/VIRB2 pilin (TrbC)

(6-90)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB2 Helicobacter pylori 26695

57.778

95.745

0.553

Multiple sequence alignment