Detailed information NTG0503568

Bioinformatically predicted

Overview

• Name: comGC
• Type: Machinery gene
• Locus tag: HWI20_RS06425
• Genome accession: NZ_CP064613
• Coordinates: 1309653..1309970 (-)
• Length: 105 a.a.
• NCBI ID: WP_001831271.1
• Uniprot ID: A0A9Q5JKE9
• Organism: Staphylococcus epidermidis strain UMCG347
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1304653..1314970

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HWI20_RS06395 (HWI20_06315)	gcvPA	1305179..1306525 (-)	1347	WP_002456181.1	aminomethyl-transferring glycine dehydrogenase subunit GcvPA	-
HWI20_RS06400 (HWI20_06320)	gcvT	1306545..1307636 (-)	1092	WP_001831107.1	glycine cleavage system aminomethyltransferase GcvT	-
HWI20_RS06405 (HWI20_06325)	-	1307854..1308366 (-)	513	WP_002440040.1	shikimate kinase	-
HWI20_RS06410 (HWI20_06330)	-	1308531..1309022 (-)	492	WP_002440043.1	competence type IV pilus minor pilin ComGF	-
HWI20_RS06415 (HWI20_06335)	-	1308946..1309239 (-)	294	WP_001831116.1	hypothetical protein	-
HWI20_RS06420 (HWI20_06340)	comGD	1309226..1309663 (-)	438	WP_001831025.1	competence type IV pilus minor pilin ComGD	-
HWI20_RS06425 (HWI20_06345)	comGC	1309653..1309970 (-)	318	WP_001831271.1	competence type IV pilus major pilin ComGC	Machinery gene
HWI20_RS06430 (HWI20_06350)	comGB	1309988..1311055 (-)	1068	WP_001831131.1	competence type IV pilus assembly protein ComGB	Machinery gene
HWI20_RS06435 (HWI20_06355)	comGA	1311027..1312001 (-)	975	WP_001831109.1	competence type IV pilus ATPase ComGA	Machinery gene
HWI20_RS06440 (HWI20_06360)	-	1312058..1312681 (-)	624	WP_001831016.1	MBL fold metallo-hydrolase	-
HWI20_RS06445 (HWI20_06365)	-	1312681..1313007 (-)	327	WP_001831234.1	MTH1187 family thiamine-binding protein	-
HWI20_RS06450 (HWI20_06370)	-	1313007..1313993 (-)	987	WP_001831113.1	ROK family glucokinase	-
HWI20_RS06455 (HWI20_06375)	-	1313993..1314193 (-)	201	WP_001831138.1	YqgQ family protein	-

Sequence

Protein

• Length: 105 a.a.
• Molecular weight: 11491.58 Da
• Isoelectric Point: 9.7429

>NTDB_id=503568 HWI20_RS06425 WP_001831271.1 1309653..1309970(-) (comGC) [Staphylococcus epidermidis strain UMCG347]
MKTLKLLKKTRAFTLIEMLLVLLIISLLLILIIPNIAKQTSHIQSTGCDAQVKMVNSQIEAYALKHNRNPSNIDDLVSDG
FIKEGQKTCKSGQTISIANGEAVAN

Nucleotide

• Length: 318 bp

>NTDB_id=503568 HWI20_RS06425 WP_001831271.1 1309653..1309970(-) (comGC) [Staphylococcus epidermidis strain UMCG347]
ATGAAAACATTGAAATTATTGAAAAAAACACGAGCATTTACCTTGATAGAAATGCTTTTAGTATTACTAATAATAAGTTT
ATTGTTAATACTTATAATTCCAAATATTGCAAAACAAACATCTCATATTCAGTCAACTGGATGTGATGCTCAAGTTAAAA
TGGTAAACAGTCAAATAGAAGCCTACGCTTTAAAACATAATCGCAACCCTTCTAATATTGATGATTTGGTTTCAGATGGT
TTTATAAAAGAAGGACAAAAAACATGTAAATCCGGTCAGACAATTAGTATTGCAAATGGAGAAGCAGTTGCCAATTAA

Domains

Predicted by InterproScan.

• Prokaryotic N-terminal methylation motif (N_methyl) (8-32)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGC	Staphylococcus aureus MW2	87.255	97.143	0.848
comGC	Staphylococcus aureus N315	87.255	97.143	0.848
comGC/cglC	Streptococcus mitis SK321	44.66	98.095	0.438
comGC/cglC	Streptococcus pneumoniae TIGR4	44.681	89.524	0.4
comGC/cglC	Streptococcus pneumoniae Rx1	44.681	89.524	0.4
comGC/cglC	Streptococcus pneumoniae D39	44.681	89.524	0.4
comGC/cglC	Streptococcus pneumoniae R6	44.681	89.524	0.4
comYC	Streptococcus mutans UA159	47.674	81.905	0.39
comYC	Streptococcus mutans UA140	47.674	81.905	0.39
comYC	Streptococcus gordonii str. Challis substr. CH1	46.512	81.905	0.381
comGC	Lactococcus lactis subsp. cremoris KW2	47.561	78.095	0.371
comGC/cglC	Streptococcus mitis NCTC 12261	50	74.286	0.371
comYC	Streptococcus suis isolate S10	48.718	74.286	0.362
comGC	Bacillus subtilis subsp. subtilis str. 168	41.758	86.667	0.362