Detailed information NTG0049710

Bioinformatically predicted

Overview

• Name: cinA
• Type: Machinery gene
• Locus tag: SSUD9_RS00405
• Genome accession: NC_017620
• Coordinates: 70362..71543 (+)
• Length: 393 a.a.
• NCBI ID: WP_004194467.1
• Uniprot ID: -
• Organism: Streptococcus suis D9
• Function: require for competence (predicted from homology) Unclear

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
IS/Tn	68548..69837	70362..71543	flank	525

Gene organization within MGE regions

Location: 68548..71543

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SSUD9_RS00395 (SSUD9_0066)	-	68548..69837 (-)	1290	WP_014636745.1	IS4-like element ISSsu2 family transposase	-
SSUD9_RS00400 (SSUD9_0067)	-	69921..70325 (+)	405	Protein_59	DNA-3-methyladenine glycosylase I	-
SSUD9_RS00405 (SSUD9_0068)	cinA	70362..71543 (+)	1182	WP_004194467.1	competence/damage-inducible protein A	Machinery gene

Sequence

Protein

• Length: 393 a.a.
• Molecular weight: 43013.95 Da
• Isoelectric Point: 4.4112

>NTDB_id=49710 SSUD9_RS00405 WP_004194467.1 70362..71543(+) (cinA) [Streptococcus suis D9]
MKAELIAVGTEILTGQIVNTNAQFLSEKCAELGIDVYFHTAVGDNEQRLLSVLEVARQRSDLVILCGGLGPTEDDLTKQI
LATFLGRNLVFDELAMAKLDRFFASRPGRVRTPNNERQAQIVEGSQALQNPAGLAVGGMIEQDGVTYIVLPGPPSELKAM
FSESLLPLLSQSQQQLYSRILRFFGIGESQLVTVLADLIDKQTDPTLAPYAKVGEVTLRLSTKATSQEEANLRLNQLEEE
ILQHDKLADYFYAYGEDNSLVKTVATRLAEKRQTIAIVEQGTGGLLQAELSLALADQPYFSGGKVIGQLGTESGRLSEEA
DCIRQELQADLGLAVSVLIKPESTEDNVLAKVYLTLATTSGISQKEIDLGGYSWQYLRQLACLQAWDFVRNTL

Nucleotide

• Length: 1182 bp

>NTDB_id=49710 SSUD9_RS00405 WP_004194467.1 70362..71543(+) (cinA) [Streptococcus suis D9]
ATGAAAGCAGAACTAATCGCCGTTGGGACGGAGATTTTGACAGGTCAAATCGTTAATACCAATGCTCAGTTCCTTTCGGA
GAAATGTGCAGAGCTGGGAATTGATGTCTATTTCCACACAGCTGTTGGAGATAATGAACAGAGGCTTCTGTCTGTACTGG
AAGTAGCCCGTCAGCGGAGCGACCTGGTCATTCTCTGTGGAGGATTGGGTCCAACTGAGGATGACTTGACCAAGCAGATC
CTGGCGACCTTCTTAGGTAGAAATCTTGTGTTTGATGAGTTGGCTATGGCAAAATTAGACCGTTTCTTTGCCAGTCGCCC
AGGTCGTGTCCGTACACCAAATAATGAACGTCAGGCACAGATTGTGGAGGGAAGTCAGGCGCTACAGAATCCAGCTGGTT
TAGCTGTTGGTGGTATGATTGAGCAAGATGGTGTAACCTATATTGTTTTGCCTGGCCCACCAAGTGAGCTCAAGGCCATG
TTTTCTGAGAGTCTCTTACCTTTACTGTCCCAATCTCAGCAGCAACTTTATTCGCGTATCCTACGTTTTTTTGGCATTGG
TGAAAGCCAGTTGGTGACTGTTTTGGCGGACTTGATCGACAAGCAGACAGACCCAACTCTTGCTCCTTATGCAAAAGTTG
GAGAGGTGACTTTACGCTTGTCCACCAAAGCGACCAGCCAAGAAGAGGCAAATCTACGTTTGAATCAGTTGGAAGAAGAA
ATCTTACAACATGACAAACTGGCAGACTATTTCTATGCCTACGGAGAGGACAATAGTTTGGTCAAAACGGTAGCGACTCG
TTTGGCGGAGAAAAGACAAACCATCGCTATCGTCGAACAGGGGACAGGTGGTCTCTTGCAAGCTGAATTAAGCCTGGCTT
TGGCTGATCAGCCGTATTTTAGCGGAGGAAAAGTCATCGGTCAGCTAGGGACAGAATCGGGCAGGCTATCAGAGGAAGCT
GACTGCATTCGGCAGGAGCTGCAAGCTGATTTGGGTTTGGCTGTGTCTGTGCTTATCAAACCGGAATCAACAGAGGACAA
CGTACTTGCAAAAGTATATCTCACTTTGGCTACGACCTCGGGTATTTCCCAAAAAGAGATAGATTTAGGTGGTTATTCGT
GGCAATACCTTCGCCAGCTTGCTTGTCTGCAGGCCTGGGATTTTGTACGAAACACTTTGTGA

Domains

Predicted by InterproScan.

• Damage-inducible protein CinA KH domain (CinA_KH) (178-253)

• Probable molybdopterin binding domain (MoCF_biosynth) (5-170)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
cinA	Streptococcus suis isolate S10	95.929	100	0.959
cinA	Streptococcus mutans UA159	56.691	100	0.593
cinA	Streptococcus pneumoniae R6	55.769	100	0.59
cinA	Streptococcus mitis SK321	55.769	100	0.59
cinA	Streptococcus pneumoniae TIGR4	55.769	100	0.59
cinA	Streptococcus pneumoniae Rx1	55.769	100	0.59
cinA	Streptococcus mitis NCTC 12261	55.529	100	0.588
cinA	Streptococcus pneumoniae D39	55.529	100	0.588
cinA	Bacillus subtilis subsp. subtilis str. 168	40.665	99.491	0.405