Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   INQ00_RS00055 Genome accession   NZ_CP063110
Coordinates   11298..11966 (-) Length   222 a.a.
NCBI ID   WP_014064026.1    Uniprot ID   -
Organism   Haemophilus parainfluenzae strain M1C160_1     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 6298..16966
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  INQ00_RS00035 (INQ00_00035) - 6595..7461 (-) 867 WP_005698439.1 MurR/RpiR family transcriptional regulator -
  INQ00_RS00040 (INQ00_00040) - 7454..8392 (-) 939 WP_197546926.1 N-acetylmannosamine kinase -
  INQ00_RS00045 (INQ00_00045) - 8404..9093 (-) 690 WP_197546927.1 N-acetylmannosamine-6-phosphate 2-epimerase -
  INQ00_RS00050 (INQ00_00050) nagE 9322..10788 (+) 1467 WP_197546928.1 N-acetylglucosamine-specific PTS transporter subunit IIBC -
  INQ00_RS00055 (INQ00_00055) crp 11298..11966 (-) 669 WP_014064026.1 cAMP-activated global transcriptional regulator CRP Regulator
  INQ00_RS00060 (INQ00_00060) - 11983..12201 (-) 219 WP_005695554.1 YheU family protein -
  INQ00_RS00065 (INQ00_00065) slmA 12223..12876 (-) 654 WP_005698358.1 nucleoid occlusion factor SlmA -
  INQ00_RS00070 (INQ00_00070) dut 12880..13335 (-) 456 WP_197546929.1 dUTP diphosphatase -
  INQ00_RS00075 (INQ00_00075) coaBC 13420..14622 (-) 1203 WP_197546930.1 bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC -
  INQ00_RS00080 (INQ00_00080) radC 14824..15489 (+) 666 WP_197546931.1 RadC family protein -
  INQ00_RS00085 (INQ00_00085) rpmB 15708..15944 (+) 237 WP_005599762.1 50S ribosomal protein L28 -
  INQ00_RS00090 (INQ00_00090) rpmG 15956..16126 (+) 171 WP_005613503.1 50S ribosomal protein L33 -

Sequence

Protein


Download         Length: 222 a.a.        Molecular weight: 25163.95 Da        Isoelectric Point: 6.6936

>NTDB_id=492872 INQ00_RS00055 WP_014064026.1 11298..11966(-) (crp) [Haemophilus parainfluenzae strain M1C160_1]
MSEDVELLEEQKLQDDDQQRDPALDWFLTHCHLHKYPAKSTLIHAGEDANILYFLIKGTVMVSSKDDEGKEMILSYLGAG
QFFGEAGLFDEGSKRSAWVKTKTPCEIAEISYKKYRQLIQINPEILMFLTSQLSKRLQNTSRQVTNLAFLDVAGRIAQAL
MHLAKQPEAMTHPDGMQIKITRQEIGQMVGCSRETVGRIIKMLEDQNLIHAHGKTIVVYGTR

Nucleotide


Download         Length: 669 bp        

>NTDB_id=492872 INQ00_RS00055 WP_014064026.1 11298..11966(-) (crp) [Haemophilus parainfluenzae strain M1C160_1]
ATGTCAGAAGATGTAGAATTACTTGAAGAACAAAAGTTACAAGACGATGATCAGCAACGCGATCCTGCTCTGGATTGGTT
CCTAACTCACTGTCATTTGCATAAATATCCTGCAAAATCGACCTTAATCCACGCAGGGGAAGATGCCAATATTTTATATT
TCTTAATTAAAGGAACGGTGATGGTTTCATCAAAAGATGATGAAGGCAAAGAGATGATTTTATCTTATTTAGGTGCTGGA
CAATTTTTTGGTGAAGCGGGTTTATTTGATGAAGGCTCGAAACGTTCTGCTTGGGTAAAAACGAAAACCCCTTGTGAAAT
TGCAGAAATTTCTTATAAAAAATATCGTCAGCTTATTCAAATTAATCCTGAGATTTTAATGTTCCTTACTTCTCAGTTAT
CAAAACGCTTGCAAAATACATCTCGACAAGTGACTAACCTGGCCTTTTTGGATGTGGCGGGGCGTATTGCTCAGGCGCTT
ATGCATCTAGCAAAACAACCTGAAGCCATGACTCATCCGGATGGCATGCAGATTAAAATTACTCGTCAGGAAATTGGTCA
AATGGTGGGCTGTTCACGTGAAACCGTAGGGCGAATAATTAAGATGCTGGAAGATCAAAATCTAATTCATGCGCACGGTA
AAACCATTGTGGTTTACGGCACTCGATAG

Domains

Predicted by InterproScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(34-120)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(154-218)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Haemophilus influenzae Rd KW20

90.909

94.144

0.856
  crp Vibrio cholerae strain A1552

73.529

91.892

0.676
  crp Acinetobacter baumannii D1279779

46.231

89.64

0.414