Detailed information NTG0049211

Bioinformatically predicted

Overview

• Name: irvR
• Type: Regulator
• Locus tag: CA347_RS10785
• Genome accession: NC_021554
• Coordinates: 2120621..2121334 (+)
• Length: 237 a.a.
• NCBI ID: WP_001031454.1
• Uniprot ID: A0A0H2XG68
• Organism: Staphylococcus aureus CA-347
• Function: regulate expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2115621..2126334

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CA347_RS15135 (CA347_2080)	-	2116823..2117086 (-)	264	WP_001205732.1	hypothetical protein	-
CA347_RS10730 (CA347_2081)	-	2117095..2117355 (-)	261	WP_000291510.1	DUF1108 family protein	-
CA347_RS10735 (CA347_2082)	-	2117360..2117662 (-)	303	WP_000165371.1	DUF2482 family protein	-
CA347_RS10740 (CA347_2083)	-	2117757..2117918 (-)	162	WP_000048129.1	DUF1270 family protein	-
CA347_RS10745 (CA347_2084)	-	2117915..2118238 (-)	324	WP_001120201.1	DUF771 domain-containing protein	-
CA347_RS10750 (CA347_2086)	-	2118293..2118673 (+)	381	WP_000762519.1	DUF2513 domain-containing protein	-
CA347_RS10755 (CA347_2085)	-	2118660..2118857 (-)	198	WP_001148862.1	hypothetical protein	-
CA347_RS10760 (CA347_2087)	-	2118873..2119625 (-)	753	WP_001148605.1	phage antirepressor KilAC domain-containing protein	-
CA347_RS10765 (CA347_2088)	-	2119676..2120005 (+)	330	WP_001622080.1	hypothetical protein	-
CA347_RS10770	-	2119994..2120209 (-)	216	WP_001025404.1	Thoeris anti-defense Tad2 family protein	-
CA347_RS10775 (CA347_2089)	-	2120225..2120488 (-)	264	WP_000854073.1	helix-turn-helix transcriptional regulator	-
CA347_RS10780	-	2120485..2120658 (-)	174	WP_001801500.1	hypothetical protein	-
CA347_RS10785 (CA347_2090)	irvR	2120621..2121334 (+)	714	WP_001031454.1	XRE family transcriptional regulator	Regulator
CA347_RS10790 (CA347_2091)	-	2121350..2122282 (+)	933	WP_000759682.1	exonuclease domain-containing protein	-
CA347_RS10795 (CA347_2092)	-	2122288..2122629 (+)	342	WP_000591749.1	hypothetical protein	-
CA347_RS10800 (CA347_2093)	-	2122833..2123015 (+)	183	WP_000705248.1	hypothetical protein	-
CA347_RS10805 (CA347_2094)	-	2123115..2123579 (+)	465	WP_000825947.1	hypothetical protein	-
CA347_RS10810 (CA347_2095)	-	2123638..2124675 (+)	1038	WP_000857191.1	tyrosine-type recombinase/integrase	-
CA347_RS10815 (CA347_2096)	sph	2124732..2125556 (+)	825	Protein_2077	sphingomyelin phosphodiesterase	-

Sequence

Protein

• Length: 237 a.a.
• Molecular weight: 27017.58 Da
• Isoelectric Point: 5.0545

>NTDB_id=49211 CA347_RS10785 WP_001031454.1 2120621..2121334(+) (irvR) [Staphylococcus aureus CA-347]
MNKERNIIIAKNIRKFLNDSNMSQKKLAELINIKPSTLSDYLNLRSNPSHGVIQRIADVFEVGKSDIDTTYKDDNDITSI
YNKLTPPRQENVLNYANEQLEEQNSKGDNVVDINSYKQEKTPVNVNGCVSAGVGERLHDETLFTEMVKGPIPTHDLALKV
NGDSMEPMFKDGEIIFVEKTHNIKNGQIGIFIIEEEAYVKKVFVEDDRLTLVSLNKDYDDLHFYRNESVRLIGKVIL

Nucleotide

• Length: 714 bp

>NTDB_id=49211 CA347_RS10785 WP_001031454.1 2120621..2121334(+) (irvR) [Staphylococcus aureus CA-347]
ATGAACAAAGAAAGAAATATTATTATAGCCAAAAACATTAGAAAATTTCTCAACGATTCAAATATGTCTCAAAAGAAACT
TGCTGAACTCATTAACATAAAACCATCTACTTTAAGCGATTATTTAAATTTACGTTCCAACCCCTCTCACGGCGTTATAC
AAAGGATAGCTGATGTTTTCGAGGTTGGTAAAAGCGACATAGATACTACATACAAAGACGATAACGACATCACTTCCATA
TACAACAAACTCACACCTCCCCGCCAAGAAAACGTACTTAACTATGCAAATGAACAATTGGAAGAACAGAATTCTAAAGG
AGATAACGTTGTAGATATTAATTCATATAAACAGGAGAAAACTCCAGTTAACGTCAATGGTTGCGTCTCTGCTGGTGTAG
GAGAACGTTTACACGATGAAACGCTATTTACTGAAATGGTTAAAGGACCTATCCCCACACACGATTTAGCGTTAAAAGTA
AATGGTGATTCTATGGAACCTATGTTTAAAGATGGCGAAATCATATTTGTGGAGAAAACTCACAATATAAAGAATGGACA
AATTGGTATATTCATCATTGAAGAAGAAGCGTACGTTAAGAAAGTCTTTGTTGAAGATGATAGATTGACTCTAGTTTCAC
TAAATAAAGATTACGACGATCTACACTTTTATAGAAATGAAAGTGTGAGGTTAATTGGAAAAGTTATTTTATAA

Domains

Predicted by InterProScan.

• Peptidase S24-like (Peptidase_S24) (127-236)

• Helix-turn-helix (HTH_3) (13-63)

3D structure

• AlphaFold DB: A0A0H2XG68

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
irvR	Streptococcus mutans UA159	33.929	100	0.401