Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA   Type   Machinery gene
Locus tag   STH8232_RS07720 Genome accession   NC_017581
Coordinates   1494177..1494872 (-) Length   231 a.a.
NCBI ID   WP_014621862.1    Uniprot ID   -
Organism   Streptococcus thermophilus JIM 8232     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1489177..1499872
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  STH8232_RS07705 (STH8232_1787) - 1489988..1490533 (-) 546 WP_014608611.1 GNAT family N-acetyltransferase -
  STH8232_RS07710 (STH8232_1788) - 1490599..1491861 (-) 1263 WP_014608612.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  STH8232_RS07715 (STH8232_1789) - 1491947..1494187 (-) 2241 WP_014621861.1 DNA internalization-related competence protein ComEC/Rec2 -
  STH8232_RS07720 (STH8232_1790) comEA 1494177..1494872 (-) 696 WP_014621862.1 helix-hairpin-helix domain-containing protein Machinery gene
  STH8232_RS07725 (STH8232_1792) - 1495242..1496114 (+) 873 WP_014621863.1 Rgg/GadR/MutR family transcriptional regulator -
  STH8232_RS07730 (STH8232_1794) - 1496400..1497533 (+) 1134 WP_231838380.1 radical SAM protein -
  STH8232_RS07735 (STH8232_1795) - 1497523..1498608 (+) 1086 WP_023909868.1 radical SAM/SPASM domain-containing protein -
  STH8232_RS07740 (STH8232_1796) - 1498595..1498858 (+) 264 WP_014621867.1 hypothetical protein -
  STH8232_RS07745 (STH8232_1797) - 1498851..1499744 (+) 894 WP_014621868.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 231 a.a.        Molecular weight: 24487.43 Da        Isoelectric Point: 4.6300

>NTDB_id=49008 STH8232_RS07720 WP_014621862.1 1494177..1494872(-) (comEA) [Streptococcus thermophilus JIM 8232]
MKEKILAYVKDNRLFVSVIAVLMVIFCFFLWMTCGAGSSMEAETSYTDVTALSTSSSKQSSQSLSEASSQSKTEGSEKVK
SKVTVDVKGAVVNPGVYTLKAGARVTDVIQEAGGMTEDADAKSVNLAASLSDEEVIYVANKDENVSVLDQTGTGQVSDKG
GQAVSKDGKINLNTATSEQLQTISGIGAKRTEDIIAYRESHGGFQSVDDLKNVSGIGDKTLDKIRESLYVA

Nucleotide


Download         Length: 696 bp        

>NTDB_id=49008 STH8232_RS07720 WP_014621862.1 1494177..1494872(-) (comEA) [Streptococcus thermophilus JIM 8232]
GTGAAGGAAAAGATTCTAGCCTATGTCAAAGATAATCGTCTGTTTGTGAGTGTCATTGCTGTACTGATGGTGATTTTTTG
CTTCTTTTTATGGATGACTTGTGGTGCCGGCAGCAGCATGGAGGCGGAGACGTCTTATACAGATGTGACAGCTTTGTCAA
CGTCTTCATCCAAACAAAGTTCACAGTCTCTTTCTGAGGCGTCTTCCCAGTCAAAGACCGAAGGAAGTGAAAAAGTTAAG
TCAAAAGTAACGGTAGATGTTAAGGGGGCTGTGGTCAATCCAGGTGTCTATACGCTAAAGGCAGGCGCTAGGGTGACAGA
TGTCATTCAAGAAGCTGGAGGAATGACAGAAGATGCAGACGCTAAGAGTGTTAACTTAGCCGCAAGCTTGTCAGATGAAG
AGGTTATTTATGTAGCCAATAAAGATGAAAATGTTTCTGTCCTTGATCAAACAGGTACTGGTCAGGTCTCTGATAAAGGA
GGGCAGGCTGTATCTAAGGATGGCAAAATTAACTTAAATACAGCAACCTCAGAGCAGTTGCAAACCATTTCTGGAATTGG
AGCTAAGCGGACAGAGGATATCATTGCCTATCGTGAAAGTCATGGCGGCTTTCAGTCCGTAGATGACTTGAAAAATGTCT
CAGGAATTGGTGATAAAACATTAGATAAAATCAGAGAGTCCCTCTATGTGGCTTAA

Domains

Predicted by InterproScan.

SLBB domain (SLBB)

(85-138)

Helix-hairpin-helix motif (HHH_3)

(167-228)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA Streptococcus thermophilus LMD-9

98.701

100

0.987
  comEA/celA/cilE Streptococcus mitis SK321

39.912

98.701

0.394
  comEA/celA/cilE Streptococcus pneumoniae D39

39.035

98.701

0.385
  comEA/celA/cilE Streptococcus pneumoniae R6

39.035

98.701

0.385
  comEA/celA/cilE Streptococcus pneumoniae Rx1

39.035

98.701

0.385
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

39.035

98.701

0.385
  comEA/celA/cilE Streptococcus mitis NCTC 12261

37.719

98.701

0.372

Multiple sequence alignment