NTDB

Overview

Name	comGB	Type	Machinery gene
Locus tag	IF710_RS07350	Genome accession	NZ_CP062372
Coordinates	1542117..1543187 (-)	Length	356 a.a.
NCBI ID	WP_000776401.1	Uniprot ID	-
Organism	Staphylococcus aureus strain NAS_AN_109
Function	dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1537117..1548187

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
IF710_RS07310 (IF710_07275)	gcvPA	1537294..1538640 (-)	1347	WP_000019681.1	aminomethyl-transferring glycine dehydrogenase subunit GcvPA	-
IF710_RS07315 (IF710_07280)	gcvT	1538660..1539751 (-)	1092	WP_000093349.1	glycine cleavage system aminomethyltransferase GcvT	-
IF710_RS07320 (IF710_07285)	-	1539910..1540434 (-)	525	WP_001015121.1	shikimate kinase	-
IF710_RS07325 (IF710_07290)	-	1540424..1540570 (-)	147	WP_001789879.1	hypothetical protein	-
IF710_RS07330 (IF710_07295)	comGF	1540667..1541164 (-)	498	WP_020978197.1	competence type IV pilus minor pilin ComGF	Machinery gene
IF710_RS07335 (IF710_07300)	comGE	1541082..1541381 (-)	300	WP_000844410.1	hypothetical protein	Machinery gene
IF710_RS07340 (IF710_07305)	comGD	1541368..1541814 (-)	447	WP_001788899.1	competence type IV pilus minor pilin ComGD	Machinery gene
IF710_RS07345 (IF710_07310)	comGC	1541792..1542103 (-)	312	WP_000472256.1	competence type IV pilus major pilin ComGC	Machinery gene
IF710_RS07350 (IF710_07315)	comGB	1542117..1543187 (-)	1071	WP_000776401.1	competence type IV pilus assembly protein ComGB	Machinery gene
IF710_RS07355 (IF710_07320)	comGA	1543159..1544133 (-)	975	WP_000697220.1	competence type IV pilus ATPase ComGA	Machinery gene
IF710_RS07360 (IF710_07325)	-	1544185..1544808 (-)	624	WP_001223008.1	MBL fold metallo-hydrolase	-
IF710_RS07365 (IF710_07330)	-	1544805..1545134 (-)	330	WP_001018871.1	MTH1187 family thiamine-binding protein	-
IF710_RS07370 (IF710_07335)	-	1545134..1546120 (-)	987	WP_000161314.1	ROK family glucokinase	-
IF710_RS07375 (IF710_07340)	-	1546117..1546320 (-)	204	WP_000087561.1	YqgQ family protein	-
IF710_RS07380 (IF710_07345)	-	1546301..1547764 (-)	1464	WP_001017871.1	rhomboid family intramembrane serine protease	-

Sequence

Protein

Download Length: 356 a.a. Molecular weight: 41508.88 Da Isoelectric Point: 9.9593

                                >NTDB_id=488701 IF710_RS07350 WP_000776401.1 1542117..1543187(-) (comGB) [Staphylococcus aureus strain NAS_AN_109]

MKLQWINTFKLHFEKRQLSKAQQIDLLSNLCNLLKYGFTLYQSFQFLNLQMTYKNKQLGTTILSEISNGAPCNQILSLIG

YSDTIVMQVYLAERFGNIIDVLEETVNYMKVNRKSEQRLLKTLQYPLILVSIFIAMIIILNLTVIPQFQQLYTSMNIQLS

SFQKTLSFFITSLPTIIVVMLIIVSMLAIIMKLIYNNLNMLNKINFVMKLPLISGYFQLFKTYFVTNELVLFYKNGITLQ

SIVDVYINHSSDPFRQFLGKYLLTYSEMGYGLPQILEKLKCFKPQLIKFVLQGEKRGKLEVELKLYSQILVKQIEDKAIK

QTQFLQPILFLILGLFIVAIYLVIMLPMFQMMQSIK

Nucleotide

Download Length: 1071 bp

                                >NTDB_id=488701 IF710_RS07350 WP_000776401.1 1542117..1543187(-) (comGB) [Staphylococcus aureus strain NAS_AN_109]

GTGAAACTACAATGGATAAATACATTTAAACTACATTTTGAGAAGCGACAATTAAGTAAGGCCCAACAAATCGATTTACT

TTCAAATTTATGTAATTTGTTGAAATATGGTTTCACTCTGTATCAAAGTTTTCAATTTTTAAATCTTCAAATGACATATA

AAAATAAGCAATTAGGTACCACCATTCTAAGTGAAATTTCAAATGGTGCACCATGCAATCAAATATTATCACTGATAGGT

TATAGCGATACTATCGTCATGCAAGTATATTTGGCAGAAAGATTTGGCAATATTATAGACGTTCTAGAAGAAACTGTAAA

TTATATGAAAGTGAATAGAAAGTCAGAACAACGATTGTTAAAGACACTGCAATACCCCTTAATACTAGTTTCTATCTTTA

TTGCTATGATTATTATATTAAACCTCACAGTAATTCCACAGTTTCAACAATTATATACTTCTATGAATATTCAACTATCT

TCTTTTCAAAAAACATTGTCTTTTTTCATTACCAGCTTACCTACTATAATTGTAGTAATGCTCATAATAGTATCTATGTT

GGCTATTATTATGAAATTAATTTATAACAATTTAAATATGCTCAATAAGATAAACTTTGTGATGAAACTACCGCTAATAT

CAGGCTATTTCCAATTATTTAAAACTTATTTTGTAACTAATGAATTAGTGTTGTTTTATAAAAATGGTATTACACTTCAA

TCAATAGTAGACGTTTATATTAACCATAGTAGTGATCCATTTAGACAGTTTCTAGGTAAATACTTATTAACTTATTCAGA

AATGGGATATGGTTTGCCTCAAATTTTAGAAAAACTAAAATGCTTTAAGCCTCAATTAATTAAGTTTGTGCTACAAGGTG

AAAAGAGAGGGAAGCTAGAAGTAGAACTAAAGTTATATTCGCAAATATTAGTAAAACAAATAGAAGATAAAGCGATAAAA

CAGACTCAGTTTTTACAGCCTATTTTATTTTTGATTTTAGGTTTATTTATTGTCGCAATTTATTTAGTAATTATGTTACC

AATGTTTCAAATGATGCAAAGTATAAAATAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(227-347)

Type II secretion system (T2SS), protein F (T2SSF)

(27-146)

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
comGB	Staphylococcus aureus MW2	99.438	100	0.994
comGB	Staphylococcus aureus N315	99.438	100	0.994

Detailed information NTG0488701