Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB4   Type   Machinery gene
Locus tag   K749_RS02360 Genome accession   NC_021216
Coordinates   472863..475232 (-) Length   789 a.a.
NCBI ID   WP_238984715.1    Uniprot ID   -
Organism   Helicobacter pylori UM299     
Function   transformation-associated type IV transport system (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 467863..480232
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  K749_RS02325 (K749_05255) infC 468433..469044 (+) 612 WP_000089218.1 translation initiation factor IF-3 -
  K749_RS02330 (K749_05260) rpmI 469025..469219 (+) 195 WP_001125547.1 50S ribosomal protein L35 -
  K749_RS02335 (K749_05265) rplT 469314..469664 (+) 351 WP_001264172.1 50S ribosomal protein L20 -
  K749_RS02340 (K749_05270) - 469864..470724 (+) 861 WP_015645552.1 outer membrane protein -
  K749_RS02350 - 471078..471266 (+) 189 Protein_464 DUF1104 domain-containing protein -
  K749_RS02355 - 471229..472860 (-) 1632 WP_015645553.1 type IA DNA topoisomerase -
  K749_RS02360 (K749_05285) comB4 472863..475232 (-) 2370 WP_238984715.1 VirB4 family type IV secretion/conjugal transfer ATPase Machinery gene
  K749_RS02365 (K749_05290) comB3 475279..475545 (-) 267 WP_015645555.1 hypothetical protein Machinery gene
  K749_RS02370 (K749_05295) - 475546..475848 (-) 303 WP_015645556.1 hypothetical protein -
  K749_RS02375 (K749_05300) - 475845..477368 (-) 1524 WP_015645557.1 hypothetical protein -
  K749_RS02380 (K749_05305) - 477375..477669 (-) 295 Protein_470 hypothetical protein -
  K749_RS08395 (K749_09090) - 477689..478467 (-) 779 Protein_471 hypothetical protein -

Sequence

Protein


Download         Length: 789 a.a.        Molecular weight: 91248.69 Da        Isoelectric Point: 7.5313

>NTDB_id=48744 K749_RS02360 WP_238984715.1 472863..475232(-) (comB4) [Helicobacter pylori UM299]
MKEETNIVGIYNEHYLFSEKSNLVGALKLEGISYLSLDDKEIVQKFNERILALNEIVDGVHFKIVAKRRKIFMHHEYTQE
EISNPFALEVINLWEQGVEDVYQNFYYLIFETKNDSIKGYLERFKKKITTNELENIQENNKQDEVKYQENYFIGFDNFNL
LDKSKILDSIINNVKNMLSGLFVEKIDANSLLNFYAEYINVIPSEYTFARGRLHDGMINSDVHFKKDFFTHIHNSKEIFK
RFISIKTYDIDKIVSTALSSVLHLSLEFDVILNIDNIPKAKAEKRIETKRKRANKSIRVEIDELNGIIKTDRVLMQEISL
NILVHAKTKTDLDSACIEITNLLKQKGIVSTQESIGMLPMFFSFFPNRNRLNFRKRLLSSQNIASLIILEKQNCGFSRNS
WGDRHLTIFKNQDKSPYLFNFHVYEAKRKNDMVSGHTIIFSGTGAGKTTLIEFLITNCFKYEDLSILALDRDNGMRVMTE
FLDGQYNDSNDFYINPFSLKDTSANCTFLVSWLAFMLNIDEDTKDEKEKKTLSALSKTIRVCYNNITKQGGAIFKLRDFK
DTLERDYLDSKDILEKESSKDLYKHSTDCLDFAKKLSVIDMDALSSSKKDFNLAVLYLFYKVMNRAKLENKPFYIFIDEA
KSVIENPIMLAKIKDTLAQARKLNGVLTLAFQDINQLDGVEGAKSIIENAAQVILYPTNNFEKLESYGILLSSIEKSFLN
KTPLNARQVLVKNLLAQSSVFLEINLEKLNSTSKKFLRAYNSSASSVFELETLKKDNPKDYKEIYLTKE

Nucleotide


Download         Length: 2370 bp        

>NTDB_id=48744 K749_RS02360 WP_238984715.1 472863..475232(-) (comB4) [Helicobacter pylori UM299]
ATGAAAGAAGAAACTAACATCGTGGGCATTTACAATGAGCATTATCTTTTCAGTGAAAAATCAAACCTTGTAGGCGCTCT
TAAGTTAGAGGGAATTTCTTATTTGTCTTTAGATGACAAAGAAATAGTGCAAAAATTTAATGAACGCATTTTAGCTCTTA
ATGAGATTGTAGATGGAGTGCATTTTAAAATCGTAGCTAAAAGGCGTAAGATTTTCATGCACCATGAATATACTCAAGAG
GAGATAAGCAATCCTTTTGCATTAGAGGTTATCAATTTATGGGAGCAAGGGGTTGAGGATGTTTATCAAAATTTCTATTA
TTTAATTTTTGAAACTAAGAATGATAGCATTAAAGGTTATTTGGAACGATTTAAGAAAAAAATCACTACCAATGAATTAG
AAAATATTCAAGAAAATAATAAACAAGATGAAGTTAAATATCAAGAAAACTATTTCATAGGCTTTGATAATTTTAATCTA
TTAGATAAATCTAAAATATTAGACAGCATTATCAATAATGTTAAAAACATGCTTTCTGGCTTGTTTGTAGAAAAAATAGA
TGCCAATAGTTTGCTTAACTTTTATGCGGAATATATCAATGTCATTCCTAGTGAATACACTTTTGCTAGAGGTCGTTTGC
ATGATGGCATGATCAATTCTGATGTGCATTTTAAAAAAGATTTTTTCACTCACATTCATAATAGTAAAGAGATTTTCAAG
CGTTTCATCAGCATTAAGACTTATGATATAGACAAAATTGTCAGCACTGCTCTTTCTTCAGTGTTGCATTTATCTTTAGA
ATTTGATGTGATTTTAAACATTGACAATATTCCTAAAGCAAAGGCTGAAAAAAGGATTGAAACTAAAAGAAAAAGAGCGA
ATAAGAGCATTAGAGTTGAAATTGATGAATTGAATGGCATTATTAAAACAGACAGGGTTTTGATGCAGGAGATTTCTTTA
AACATTTTAGTTCATGCCAAAACTAAAACCGATTTAGATAGTGCTTGTATAGAAATTACCAACTTGCTTAAACAAAAAGG
TATTGTAAGCACACAAGAGAGTATTGGTATGTTGCCTATGTTTTTTAGCTTTTTCCCCAATCGTAATCGCTTGAATTTTA
GAAAGCGTTTGTTGTCTAGTCAAAATATTGCTTCTTTAATCATATTGGAAAAACAAAATTGTGGTTTTTCTAGAAATTCA
TGGGGTGATCGCCATTTAACTATTTTTAAAAACCAAGACAAATCGCCTTATTTATTCAATTTCCATGTTTATGAGGCAAA
AAGAAAAAATGATATGGTATCAGGGCATACCATCATCTTTAGTGGCACAGGGGCTGGTAAAACCACTTTAATTGAATTTT
TAATCACCAATTGTTTTAAGTATGAAGATTTAAGTATTTTGGCTTTAGACAGAGATAATGGCATGCGTGTGATGACTGAG
TTTTTAGATGGTCAATACAACGATAGCAATGATTTTTACATTAATCCGTTTTCTTTAAAAGATACAAGCGCTAATTGCAC
CTTTTTAGTGAGTTGGTTGGCATTCATGCTCAATATTGATGAAGATACTAAAGATGAAAAAGAAAAAAAGACTTTAAGCG
CTTTATCCAAAACGATCAGAGTTTGCTATAACAATATCACAAAACAAGGGGGTGCTATTTTTAAGTTAAGAGATTTTAAA
GACACGCTAGAAAGAGACTATTTAGATAGTAAAGACATTTTAGAAAAAGAAAGCTCAAAAGACTTATACAAGCATTCTAC
TGATTGTTTAGACTTTGCTAAAAAGCTTTCTGTTATTGATATGGATGCTCTTTCTAGTAGTAAAAAAGATTTCAACTTGG
CAGTGCTATACCTATTCTACAAAGTCATGAATAGAGCTAAATTAGAAAACAAGCCTTTTTATATCTTCATTGATGAAGCA
AAATCTGTTATTGAAAATCCCATCATGTTAGCTAAAATCAAAGACACACTCGCTCAAGCTAGAAAACTCAATGGGGTTTT
AACTTTAGCCTTTCAAGACATTAACCAACTTGATGGTGTAGAGGGAGCAAAGTCCATTATAGAAAACGCCGCTCAAGTCA
TACTCTATCCTACAAACAATTTTGAGAAATTAGAGAGCTATGGCATTTTATTAAGTTCTATTGAAAAATCATTTTTAAAC
AAAACGCCGTTAAACGCTAGGCAAGTATTAGTGAAAAACCTTCTCGCTCAATCTAGCGTATTTTTAGAAATCAATTTAGA
AAAGCTAAACAGCACCAGTAAAAAATTTTTAAGAGCGTATAACTCTAGTGCATCTAGCGTTTTTGAACTAGAAACGCTTA
AAAAGGATAACCCAAAGGATTATAAAGAAATTTACTTGACAAAGGAGTAG

Domains

Predicted by InterProScan.

CagE, TrbE, VirB family, component of type IV transporter system (CagE_TrbE_VirB)

(176-374)

TraM recognition site of TraD and TraG (TraG-D_C)

(632-707)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB4 Helicobacter pylori 26695

35.849

100

0.361