Detailed information NTG0048709

Bioinformatically predicted

Overview

• Name: endA
• Type: Machinery gene
• Locus tag: STND_RS05430
• Genome accession: NC_017563
• Coordinates: 1017108..1017989 (-)
• Length: 293 a.a.
• NCBI ID: WP_014608376.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus ND03
• Function: cleavage of dsDNA into ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1012108..1022989

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
STND_RS05405 (STND_1078)	vicR	1012812..1013519 (-)	708	WP_011681206.1	response regulator YycF	Regulator
STND_RS05410 (STND_1079)	-	1014046..1014813 (+)	768	WP_014608372.1	amino acid ABC transporter ATP-binding protein	-
STND_RS05415 (STND_1080)	-	1014825..1015658 (+)	834	WP_014608373.1	transporter substrate-binding domain-containing protein	-
STND_RS05420 (STND_1081)	-	1015676..1016374 (+)	699	WP_014608374.1	amino acid ABC transporter permease	-
STND_RS05425 (STND_1082)	-	1016386..1017036 (+)	651	WP_014608375.1	amino acid ABC transporter permease	-
STND_RS05430 (STND_1083)	endA	1017108..1017989 (-)	882	WP_014608376.1	DNA/RNA non-specific endonuclease	Machinery gene
STND_RS05435 (STND_1084)	-	1018051..1018239 (-)	189	WP_011226090.1	DNA-directed RNA polymerase subunit beta	-
STND_RS05440 (STND_1085)	murA	1018241..1019512 (-)	1272	WP_014608377.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
STND_RS05445 (STND_1086)	-	1019582..1019818 (-)	237	WP_002946959.1	DUF1146 family protein	-
STND_RS05450 (STND_1087)	galE	1020006..1021019 (-)	1014	WP_014608379.1	UDP-glucose 4-epimerase GalE	-
STND_RS09710	-	1021034..1021537 (-)	504	WP_224102963.1	DUF4832 domain-containing protein	-
STND_RS09715	-	1021527..1021979 (-)	453	WP_011681214.1	hypothetical protein	-

Sequence

Protein

• Length: 293 a.a.
• Molecular weight: 31774.44 Da
• Isoelectric Point: 10.0477

>NTDB_id=48709 STND_RS05430 WP_014608376.1 1017108..1017989(-) (endA) [Streptococcus thermophilus ND03]
MAKRETSLTNKQKRQLVTLIIAALIAVLGYLGTSNKLSPDNPIRQVASLVSGKSNKSIKSNGSTNSQSTPQEQLAETVMT
SSVKSQLGNSLEWNGAGAYIINRNKTNLNAKVSSQPYANNQVKTVQGQTVPTVANALLSKATRQYKNRQETGNGSTSWTP
AGWHQVQNLSGEYSHAVDRGHLLGYALIGGLKGFDASTSNPENIAVQTAWANQAYSDSSTGQNYYESLVRKALDKNKRVR
YRVTLIYEGENLIPSGTHLEAKSADGSLEFNVFVPNVQEGITLDYYSGKVTVN

Nucleotide

• Length: 882 bp

>NTDB_id=48709 STND_RS05430 WP_014608376.1 1017108..1017989(-) (endA) [Streptococcus thermophilus ND03]
ATGGCAAAAAGAGAGACATCTTTGACAAATAAACAGAAACGTCAGTTAGTCACATTAATAATAGCAGCTTTGATAGCTGT
TTTAGGTTACCTAGGAACCAGTAACAAGCTCTCGCCTGATAATCCTATCAGACAAGTAGCAAGCCTAGTTTCAGGGAAAT
CTAACAAATCCATTAAATCTAATGGTTCAACAAATAGTCAGTCTACACCACAAGAGCAGCTTGCTGAGACAGTAATGACT
AGTTCAGTCAAAAGCCAACTGGGTAATTCCTTAGAATGGAATGGAGCTGGGGCCTACATTATTAATAGAAATAAGACGAA
TCTAAATGCTAAGGTATCAAGCCAACCCTATGCTAATAACCAAGTCAAAACGGTTCAAGGACAAACTGTTCCTACAGTTG
CTAATGCCTTATTAAGTAAAGCAACTAGACAGTACAAAAATCGTCAAGAAACAGGGAATGGTTCAACCTCTTGGACACCA
GCTGGATGGCACCAGGTTCAAAATTTATCAGGAGAGTATAGCCATGCCGTAGATAGAGGCCATTTGCTAGGTTATGCACT
GATAGGTGGTTTGAAAGGATTTGATGCCTCGACTTCAAATCCAGAGAATATTGCTGTTCAAACTGCTTGGGCAAATCAAG
CATATAGCGATAGTTCTACAGGCCAAAACTATTATGAAAGCCTAGTACGAAAAGCTCTGGATAAAAACAAACGTGTTCGT
TATCGTGTGACCCTGATTTATGAAGGAGAGAATCTCATTCCATCAGGAACACATCTTGAAGCTAAGTCAGCAGACGGCTC
ACTTGAGTTTAATGTCTTTGTTCCAAATGTACAAGAGGGAATTACACTAGATTACTATTCAGGAAAAGTAACGGTGAATT
GA

Domains

Predicted by InterproScan.

• DNA/RNA non-specific endonuclease (Endonuclease_NS) (101-266)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
endA	Streptococcus pneumoniae Rx1	72.803	81.57	0.594
endA	Streptococcus pneumoniae D39	72.803	81.57	0.594
endA	Streptococcus pneumoniae R6	72.803	81.57	0.594
endA	Streptococcus pneumoniae TIGR4	72.803	81.57	0.594