Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGE   Type   Machinery gene
Locus tag   J7U23_RS09015 Genome accession   NZ_CP072435
Coordinates   1746529..1746822 (-) Length   97 a.a.
NCBI ID   WP_011226625.1    Uniprot ID   Q5M2G2
Organism   Streptococcus thermophilus strain S24736     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1741529..1751822
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  J7U23_RS08980 (J7U23_08875) - 1741931..1742224 (-) 294 WP_232085688.1 hypothetical protein -
  J7U23_RS08985 - 1742449..1742874 (-) 426 WP_111679733.1 CPBP family intramembrane glutamic endopeptidase -
  J7U23_RS08990 (J7U23_08885) - 1743117..1743314 (-) 198 WP_002885716.1 helix-turn-helix transcriptional regulator -
  J7U23_RS08995 (J7U23_08890) - 1743563..1744756 (-) 1194 WP_084831204.1 acetate kinase -
  J7U23_RS09000 (J7U23_08895) comGH 1744812..1745768 (-) 957 WP_011226622.1 class I SAM-dependent methyltransferase Machinery gene
  J7U23_RS09005 (J7U23_08900) comGG 1745813..1746130 (-) 318 WP_082309152.1 competence type IV pilus minor pilin ComGG Machinery gene
  J7U23_RS09010 (J7U23_08905) comGF 1746108..1746545 (-) 438 WP_082309153.1 competence type IV pilus minor pilin ComGF Machinery gene
  J7U23_RS09015 (J7U23_08910) comGE 1746529..1746822 (-) 294 WP_011226625.1 competence type IV pilus minor pilin ComGE Machinery gene
  J7U23_RS09020 (J7U23_08915) comGD 1746794..1747222 (-) 429 WP_011226626.1 competence type IV pilus minor pilin ComGD Machinery gene
  J7U23_RS09025 (J7U23_08920) comGC 1747182..1747508 (-) 327 WP_002946126.1 competence type IV pilus major pilin ComGC Machinery gene
  J7U23_RS09030 (J7U23_08925) comGB 1747505..1748605 (-) 1101 WP_271307389.1 competence type IV pilus assembly protein ComGB Machinery gene
  J7U23_RS09035 (J7U23_08930) comGA 1748487..1749428 (-) 942 WP_372589905.1 competence type IV pilus ATPase ComGA Machinery gene
  J7U23_RS09040 (J7U23_08935) - 1749509..1749871 (-) 363 WP_372433446.1 DUF1033 family protein -

Sequence

Protein


Download         Length: 97 a.a.        Molecular weight: 10844.74 Da        Isoelectric Point: 10.4561

>NTDB_id=482822 J7U23_RS09015 WP_011226625.1 1746529..1746822(-) (comGE) [Streptococcus thermophilus strain S24736]
MVNIKRRSLRGYILIESLVAMAVLVLVSSLILEQINTNRRLMADNLHQQEVLSVATMAVQTKQDQLTLNGIAVTVKRSQQ
GITVYESGKEIIHVSKQ

Nucleotide


Download         Length: 294 bp        

>NTDB_id=482822 J7U23_RS09015 WP_011226625.1 1746529..1746822(-) (comGE) [Streptococcus thermophilus strain S24736]
GTGGTAAATATAAAAAGACGATCTCTTAGAGGTTATATTCTTATTGAAAGTCTGGTAGCTATGGCTGTTTTAGTACTTGT
CAGCAGTCTGATATTGGAACAAATTAATACCAACCGCAGACTAATGGCTGATAATCTCCATCAACAAGAGGTCTTGAGTG
TGGCAACAATGGCAGTTCAGACCAAGCAAGACCAGTTAACGCTGAATGGCATAGCGGTGACAGTTAAACGTAGCCAGCAA
GGTATCACGGTTTATGAATCAGGAAAGGAGATTATTCATGTATCTAAGCAGTAA

Domains

Predicted by InterProScan.

Type II secretory pathway pseudopilin (ComGE)

(13-94)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q5M2G2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE Streptococcus mutans UA140

43.299

100

0.433
  comGE Streptococcus mutans UA159

43.299

100

0.433
  comGE Lactococcus lactis subsp. cremoris KW2

36.082

100

0.361