Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGE   Type   Machinery gene
Locus tag   J7T96_RS08885 Genome accession   NZ_CP072434
Coordinates   1702235..1702528 (-) Length   97 a.a.
NCBI ID   WP_011226625.1    Uniprot ID   Q5M2G2
Organism   Streptococcus thermophilus strain S24742     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1697235..1707528
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  J7T96_RS08850 (J7T96_08705) - 1697639..1698082 (-) 444 WP_084829882.1 CAAX protease -
  J7T96_RS08855 - 1698156..1698581 (-) 426 WP_087010196.1 CPBP family intramembrane glutamic endopeptidase -
  J7T96_RS08860 (J7T96_08715) - 1698823..1699020 (-) 198 WP_014727723.1 helix-turn-helix transcriptional regulator -
  J7T96_RS08865 (J7T96_08720) - 1699269..1700462 (-) 1194 WP_084831204.1 acetate kinase -
  J7T96_RS08870 (J7T96_08725) comGH 1700518..1701474 (-) 957 WP_207559851.1 class I SAM-dependent methyltransferase Machinery gene
  J7T96_RS08875 (J7T96_08730) comGG 1701519..1701836 (-) 318 WP_082309152.1 competence type IV pilus minor pilin ComGG Machinery gene
  J7T96_RS08880 (J7T96_08735) comGF 1701814..1702251 (-) 438 WP_082309153.1 competence type IV pilus minor pilin ComGF Machinery gene
  J7T96_RS08885 (J7T96_08740) comGE 1702235..1702528 (-) 294 WP_011226625.1 competence type IV pilus minor pilin ComGE Machinery gene
  J7T96_RS08890 (J7T96_08745) comGD 1702500..1702928 (-) 429 WP_011226626.1 competence type IV pilus minor pilin ComGD Machinery gene
  J7T96_RS08895 (J7T96_08750) comGC 1702888..1703214 (-) 327 WP_002946126.1 competence type IV pilus major pilin ComGC Machinery gene
  J7T96_RS08900 (J7T96_08755) comGB 1703211..1704311 (-) 1101 WP_207559852.1 competence type IV pilus assembly protein ComGB Machinery gene
  J7T96_RS08905 (J7T96_08760) comGA/cglA/cilD 1704193..1705134 (-) 942 WP_014608745.1 competence type IV pilus ATPase ComGA Machinery gene
  J7T96_RS08910 (J7T96_08765) - 1705215..1705577 (-) 363 WP_014608746.1 DUF1033 family protein -

Sequence

Protein


Download         Length: 97 a.a.        Molecular weight: 10844.74 Da        Isoelectric Point: 10.4561

>NTDB_id=482718 J7T96_RS08885 WP_011226625.1 1702235..1702528(-) (comGE) [Streptococcus thermophilus strain S24742]
MVNIKRRSLRGYILIESLVAMAVLVLVSSLILEQINTNRRLMADNLHQQEVLSVATMAVQTKQDQLTLNGIAVTVKRSQQ
GITVYESGKEIIHVSKQ

Nucleotide


Download         Length: 294 bp        

>NTDB_id=482718 J7T96_RS08885 WP_011226625.1 1702235..1702528(-) (comGE) [Streptococcus thermophilus strain S24742]
GTGGTAAATATAAAAAGACGATCTCTTAGAGGTTATATTCTTATTGAAAGTCTGGTAGCTATGGCTGTTTTAGTACTTGT
CAGCAGTCTGATATTGGAACAAATTAATACCAACCGCAGACTAATGGCTGATAATCTCCATCAACAAGAGGTCTTGAGTG
TGGCAACAATGGCAGTTCAGACCAAGCAAGACCAGTTAACGCTGAATGGCATAGCGGTGACAGTTAAACGTAGCCAGCAA
GGTATCACGGTTTATGAATCAGGAAAGGAGATTATTCATGTATCTAAGCAGTAA

Domains

Predicted by InterProScan.

Type II secretory pathway pseudopilin (ComGE)

(13-94)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q5M2G2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE Streptococcus mutans UA140

43.299

100

0.433
  comGE Streptococcus mutans UA159

43.299

100

0.433
  comGE Lactococcus lactis subsp. cremoris KW2

36.082

100

0.361