Detailed information NTG0482697

Bioinformatically predicted

Overview

• Name: codY
• Type: Regulator
• Locus tag: J7T96_RS07790
• Genome accession: NZ_CP072434
• Coordinates: 1492347..1493132 (-)
• Length: 261 a.a.
• NCBI ID: WP_002951720.1
• Uniprot ID: Q5M305
• Organism: Streptococcus thermophilus strain S24742
• Function: repress the expression of comX (predicted from homology) Competence regulation

Genomic Context

Location: 1487347..1498132

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
J7T96_RS07755 (J7T96_07625)	gatC	1487410..1487712 (-)	303	WP_002884769.1	Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC	-
J7T96_RS07760 (J7T96_07630)	-	1487852..1488106 (-)	255	WP_095559434.1	glycosyltransferase	-
J7T96_RS07765 (J7T96_07635)	-	1488119..1488328 (-)	210	WP_080998437.1	glycosyltransferase	-
J7T96_RS07770 (J7T96_07640)	-	1488644..1490088 (-)	1445	Protein_1478	6-phospho-beta-glucosidase	-
J7T96_RS07775 (J7T96_07645)	msrA	1490241..1490750 (-)	510	WP_041827375.1	peptide-methionine (S)-S-oxide reductase MsrA	-
J7T96_RS07780 (J7T96_07650)	-	1490762..1491610 (-)	849	WP_041828318.1	MetQ/NlpA family ABC transporter substrate-binding protein	-
J7T96_RS07785 (J7T96_07655)	-	1491733..1492284 (-)	552	WP_084829819.1	cysteine hydrolase family protein	-
J7T96_RS07790 (J7T96_07660)	codY	1492347..1493132 (-)	786	WP_002951720.1	GTP-sensing pleiotropic transcriptional regulator CodY	Regulator
J7T96_RS07795 (J7T96_07665)	-	1493392..1494606 (-)	1215	WP_011226456.1	pyridoxal phosphate-dependent aminotransferase	-
J7T96_RS07800 (J7T96_07670)	-	1494961..1495413 (+)	453	WP_002946987.1	universal stress protein	-
J7T96_RS07805	-	1495590..1496164 (+)	575	Protein_1485	IS30 family transposase	-
J7T96_RS07810 (J7T96_07675)	-	1496236..1496409 (-)	174	WP_011681546.1	hypothetical protein	-
J7T96_RS07815 (J7T96_07680)	-	1496470..1496844 (-)	375	WP_011681547.1	membrane protein	-
J7T96_RS07820 (J7T96_07685)	pflA	1497056..1497856 (-)	801	WP_002946980.1	pyruvate formate-lyase-activating protein	-

Sequence

Protein

• Length: 261 a.a.
• Molecular weight: 28919.13 Da
• Isoelectric Point: 4.5802

>NTDB_id=482697 J7T96_RS07790 WP_002951720.1 1492347..1493132(-) (codY) [Streptococcus thermophilus strain S24742]
MANLLDKTRKITSILQRSVDSLEGDLPYNNMAAQLADIIDCNAAIVNGGGALLGFAMKYKTNNDRVEKFFKAKQLPEEYI
RGISRVYDTQENIGIDSDLTIFPVELKDDFPDGLTTIAPIYGGGMRLGSFIIWRNDHDFVDDDLILVEIASTVVGLQLLH
LQTENLEETIRKQTAINMAINTLSYSEIKAVSAILNELDGLEGRLTASVIADRIGITRSVIVNALRKLESAGIIESRSLG
MKGTYLKVLNEGIYDKLKEYE

Nucleotide

• Length: 786 bp

>NTDB_id=482697 J7T96_RS07790 WP_002951720.1 1492347..1493132(-) (codY) [Streptococcus thermophilus strain S24742]
ATGGCAAATTTGCTTGATAAAACACGTAAAATTACTTCTATCTTGCAACGCTCAGTAGATAGTTTGGAAGGAGATCTTCC
ATACAACAACATGGCTGCTCAGTTGGCAGATATTATTGATTGTAATGCTGCTATTGTAAATGGTGGAGGTGCTCTCCTTG
GTTTTGCTATGAAATACAAAACCAACAATGACCGTGTGGAAAAGTTTTTTAAAGCTAAACAACTTCCAGAGGAATACATA
CGTGGTATCAGTCGTGTTTATGATACTCAAGAAAATATCGGTATTGACAGTGACTTGACCATCTTCCCAGTGGAATTAAA
AGATGATTTCCCTGACGGTTTGACTACAATTGCACCAATCTATGGTGGTGGTATGCGTCTTGGTTCTTTCATTATTTGGC
GTAACGACCATGATTTTGTGGACGACGACCTTATCTTGGTTGAGATTGCATCTACAGTAGTTGGTTTGCAATTGTTGCAT
CTTCAAACAGAAAACTTGGAAGAAACGATTCGTAAACAAACAGCTATTAATATGGCTATTAATACCTTGTCTTACTCAGA
AATCAAGGCAGTTTCAGCTATCTTGAATGAGTTGGACGGTTTAGAAGGTCGTTTGACAGCCTCTGTTATCGCGGACCGTA
TCGGAATTACTCGTTCTGTTATTGTTAATGCTCTTCGTAAATTAGAATCAGCTGGTATTATTGAAAGTCGTTCGCTTGGT
ATGAAAGGCACTTACCTTAAAGTCCTTAACGAAGGTATCTACGACAAATTGAAAGAATACGAATAA

Domains

Predicted by InterProScan.

• CodY GAF-like domain (CodY) (3-182)

• CodY helix-turn-helix domain (HTH_CodY) (201-261)

3D structure

• AlphaFold DB: Q5M305

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
codY	Lactococcus lactis subsp. lactis strain DGCC12653	64.591	98.467	0.636
codY	Bacillus subtilis subsp. subtilis str. 168	53.036	94.636	0.502