NTDB

Overview

Name	codY	Type	Regulator
Locus tag	J7T77_RS07710	Genome accession	NZ_CP072430
Coordinates	1483051..1483836 (-)	Length	261 a.a.
NCBI ID	WP_002951720.1	Uniprot ID	Q5M305
Organism	Streptococcus thermophilus strain S24746
Function	repress the expression of comX (predicted from homology) Competence regulation

Genomic Context

Location: 1478051..1488836

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
J7T77_RS07675 (J7T77_07560)	gatC	1478115..1478417 (-)	303	WP_002884769.1	Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC	-
J7T77_RS07680 (J7T77_07565)	-	1478557..1478811 (-)	255	WP_041827766.1	glycosyl transferase	-
J7T77_RS07685	-	1478750..1479034 (-)	285	WP_372589658.1	glycosyltransferase	-
J7T77_RS07690 (J7T77_07575)	-	1479350..1480791 (-)	1442	Protein_1461	6-phospho-beta-glucosidase	-
J7T77_RS07695 (J7T77_07580)	msrA	1480944..1481453 (-)	510	WP_232992575.1	peptide-methionine (S)-S-oxide reductase MsrA	-
J7T77_RS07700 (J7T77_07585)	-	1481465..1482313 (-)	849	WP_014608646.1	MetQ/NlpA family ABC transporter substrate-binding protein	-
J7T77_RS07705 (J7T77_07590)	-	1482437..1482988 (-)	552	WP_002946999.1	cysteine hydrolase family protein	-
J7T77_RS07710 (J7T77_07595)	codY	1483051..1483836 (-)	786	WP_002951720.1	GTP-sensing pleiotropic transcriptional regulator CodY	Regulator
J7T77_RS07715 (J7T77_07600)	-	1484096..1485310 (-)	1215	WP_002951721.1	pyridoxal phosphate-dependent aminotransferase	-
J7T77_RS07720 (J7T77_07605)	-	1485665..1486117 (+)	453	WP_002946987.1	universal stress protein	-
J7T77_RS07725	-	1486297..1486868 (+)	572	Protein_1468	IS30 family transposase	-
J7T77_RS07730 (J7T77_07610)	-	1486940..1487113 (-)	174	WP_011681546.1	hypothetical protein	-
J7T77_RS07735 (J7T77_07615)	-	1487174..1487548 (-)	375	WP_011681547.1	membrane protein	-

Sequence

Protein

Download Length: 261 a.a. Molecular weight: 28919.13 Da Isoelectric Point: 4.5802

                                >NTDB_id=482401 J7T77_RS07710 WP_002951720.1 1483051..1483836(-) (codY) [Streptococcus thermophilus strain S24746]

MANLLDKTRKITSILQRSVDSLEGDLPYNNMAAQLADIIDCNAAIVNGGGALLGFAMKYKTNNDRVEKFFKAKQLPEEYI

RGISRVYDTQENIGIDSDLTIFPVELKDDFPDGLTTIAPIYGGGMRLGSFIIWRNDHDFVDDDLILVEIASTVVGLQLLH

LQTENLEETIRKQTAINMAINTLSYSEIKAVSAILNELDGLEGRLTASVIADRIGITRSVIVNALRKLESAGIIESRSLG

MKGTYLKVLNEGIYDKLKEYE

Nucleotide

Download Length: 786 bp

                                >NTDB_id=482401 J7T77_RS07710 WP_002951720.1 1483051..1483836(-) (codY) [Streptococcus thermophilus strain S24746]

ATGGCAAATTTGCTTGATAAAACACGTAAAATTACTTCTATCTTGCAACGCTCAGTAGATAGTTTGGAAGGAGATCTTCC

ATACAACAACATGGCTGCTCAGTTGGCAGATATTATTGATTGTAATGCTGCTATTGTAAATGGTGGAGGTGCTCTCCTTG

GTTTTGCTATGAAATACAAAACCAACAATGACCGTGTGGAAAAGTTTTTTAAAGCTAAACAACTTCCAGAGGAATACATA

CGTGGTATCAGCCGTGTTTATGATACTCAAGAAAATATCGGTATTGACAGTGACTTGACCATCTTCCCAGTGGAATTAAA

AGATGATTTCCCTGACGGTTTGACTACAATTGCACCAATCTATGGTGGTGGTATGCGTCTTGGTTCTTTCATTATTTGGC

GTAACGACCATGATTTTGTGGACGACGACCTTATCTTGGTTGAGATTGCATCTACAGTAGTTGGTTTGCAATTGTTGCAT

CTTCAAACAGAAAACTTGGAAGAAACGATTCGTAAACAAACAGCTATTAATATGGCTATTAATACCTTGTCTTACTCAGA

AATCAAGGCAGTTTCAGCTATCTTGAATGAGTTGGACGGTTTAGAAGGTCGTTTGACAGCCTCTGTTATCGCGGACCGTA

TCGGAATTACTCGTTCTGTTATTGTTAATGCTCTTCGTAAATTAGAATCAGCTGGTATTATTGAAAGTCGTTCGCTTGGT

ATGAAAGGCACTTACCTTAAAGTCCTTAACGAAGGTATCTACGACAAATTGAAAGAATACGAATAA

Domains

Predicted by InterProScan.

CodY GAF-like domain (CodY)

(3-182)

CodY helix-turn-helix domain (HTH_CodY)

(201-261)

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure
AlphaFold DB	Q5M305

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
codY	Lactococcus lactis subsp. lactis strain DGCC12653	64.591	98.467	0.636
codY	Bacillus subtilis subsp. subtilis str. 168	53.036	94.636	0.502

Detailed information NTG0482401