Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGE   Type   Machinery gene
Locus tag   J7T92_RS08900 Genome accession   NZ_CP072429
Coordinates   1699489..1699782 (-) Length   97 a.a.
NCBI ID   WP_011226625.1    Uniprot ID   Q5M2G2
Organism   Streptococcus thermophilus strain S24747     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1694489..1704782
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  J7T92_RS08865 (J7T92_08840) - 1694890..1695333 (-) 444 WP_041829335.1 hypothetical protein -
  J7T92_RS08870 - 1695407..1695745 (-) 339 WP_224103197.1 CPBP family intramembrane glutamic endopeptidase -
  J7T92_RS08875 (J7T92_08850) - 1696077..1696274 (-) 198 WP_014727723.1 helix-turn-helix transcriptional regulator -
  J7T92_RS08880 (J7T92_08855) - 1696523..1697716 (-) 1194 WP_014608740.1 acetate kinase -
  J7T92_RS08885 (J7T92_08860) comGH 1697772..1698728 (-) 957 WP_372434691.1 class I SAM-dependent methyltransferase Machinery gene
  J7T92_RS08890 (J7T92_08865) comGG 1698773..1699090 (-) 318 WP_011681685.1 competence type IV pilus minor pilin ComGG Machinery gene
  J7T92_RS08895 (J7T92_08870) comGF 1699068..1699505 (-) 438 WP_011681686.1 competence type IV pilus minor pilin ComGF Machinery gene
  J7T92_RS08900 (J7T92_08875) comGE 1699489..1699782 (-) 294 WP_011226625.1 competence type IV pilus minor pilin ComGE Machinery gene
  J7T92_RS08905 (J7T92_08880) comGD 1699754..1700182 (-) 429 WP_011226626.1 competence type IV pilus minor pilin ComGD Machinery gene
  J7T92_RS08910 (J7T92_08885) comGC 1700142..1700468 (-) 327 WP_002946126.1 competence type IV pilus major pilin ComGC Machinery gene
  J7T92_RS08915 (J7T92_08890) comGB 1700465..1701564 (-) 1100 Protein_1699 competence type IV pilus assembly protein ComGB -
  J7T92_RS08920 (J7T92_08895) comGA/cglA/cilD 1701446..1702387 (-) 942 WP_071417491.1 competence type IV pilus ATPase ComGA Machinery gene
  J7T92_RS08925 (J7T92_08900) - 1702468..1702830 (-) 363 WP_014622006.1 DUF1033 family protein -

Sequence

Protein


Download         Length: 97 a.a.        Molecular weight: 10844.74 Da        Isoelectric Point: 10.4561

>NTDB_id=482320 J7T92_RS08900 WP_011226625.1 1699489..1699782(-) (comGE) [Streptococcus thermophilus strain S24747]
MVNIKRRSLRGYILIESLVAMAVLVLVSSLILEQINTNRRLMADNLHQQEVLSVATMAVQTKQDQLTLNGIAVTVKRSQQ
GITVYESGKEIIHVSKQ

Nucleotide


Download         Length: 294 bp        

>NTDB_id=482320 J7T92_RS08900 WP_011226625.1 1699489..1699782(-) (comGE) [Streptococcus thermophilus strain S24747]
GTGGTAAATATAAAAAGACGATCTCTTAGAGGTTATATTCTTATTGAAAGTCTGGTAGCTATGGCTGTTTTAGTACTTGT
CAGCAGTCTGATATTGGAACAAATTAATACCAACCGCAGACTAATGGCTGATAATCTCCATCAACAAGAGGTCTTGAGTG
TGGCAACAATGGCAGTTCAGACCAAGCAAGACCAGTTAACGCTGAATGGCATAGCGGTGACAGTTAAACGTAGCCAGCAA
GGTATCACGGTTTATGAATCGGGAAAGGAGATTATTCATGTATCTAAGCAGTAA

Domains

Predicted by InterProScan.

Type II secretory pathway pseudopilin (ComGE)

(13-94)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q5M2G2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE Streptococcus mutans UA140

43.299

100

0.433
  comGE Streptococcus mutans UA159

43.299

100

0.433
  comGE Lactococcus lactis subsp. cremoris KW2

36.082

100

0.361