Detailed information NTG0482301

Bioinformatically predicted

Overview

• Name: codY
• Type: Regulator
• Locus tag: J7T92_RS07805
• Genome accession: NZ_CP072429
• Coordinates: 1488303..1489088 (-)
• Length: 261 a.a.
• NCBI ID: WP_002951720.1
• Uniprot ID: Q5M305
• Organism: Streptococcus thermophilus strain S24747
• Function: repress the expression of comX (predicted from homology) Competence regulation

Genomic Context

Location: 1483303..1494088

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
J7T92_RS07770 (J7T92_07745)	gatC	1483366..1483668 (-)	303	WP_002884769.1	Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC	-
J7T92_RS07775 (J7T92_07750)	-	1483808..1484062 (-)	255	WP_024010053.1	glycosyl transferase	-
J7T92_RS07780 (J7T92_07755)	-	1484075..1484284 (-)	210	WP_080998437.1	glycosyltransferase	-
J7T92_RS07785 (J7T92_07760)	-	1484600..1486043 (-)	1444	Protein_1480	6-phospho-beta-glucosidase	-
J7T92_RS07790 (J7T92_07765)	msrA	1486196..1486705 (-)	510	WP_041827375.1	peptide-methionine (S)-S-oxide reductase MsrA	-
J7T92_RS07795 (J7T92_07770)	-	1486717..1487565 (-)	849	Protein_1482	MetQ/NlpA family ABC transporter substrate-binding protein	-
J7T92_RS07800 (J7T92_07775)	-	1487689..1488240 (-)	552	WP_002946999.1	cysteine hydrolase family protein	-
J7T92_RS07805 (J7T92_07780)	codY	1488303..1489088 (-)	786	WP_002951720.1	GTP-sensing pleiotropic transcriptional regulator CodY	Regulator
J7T92_RS07810 (J7T92_07785)	-	1489348..1490562 (-)	1215	WP_002951721.1	pyridoxal phosphate-dependent aminotransferase	-
J7T92_RS07815 (J7T92_07790)	-	1490917..1491369 (+)	453	WP_002946987.1	universal stress protein	-
J7T92_RS07820 (J7T92_07795)	-	1491549..1492120 (+)	572	Protein_1487	IS30 family transposase	-
J7T92_RS07825 (J7T92_07800)	-	1492192..1492365 (-)	174	WP_014621904.1	hypothetical protein	-
J7T92_RS07830 (J7T92_07805)	-	1492426..1492800 (-)	375	WP_232971393.1	hypothetical protein	-
J7T92_RS07835 (J7T92_07810)	pflA	1493012..1493812 (-)	801	WP_071417327.1	pyruvate formate-lyase-activating protein	-

Sequence

Protein

• Length: 261 a.a.
• Molecular weight: 28919.13 Da
• Isoelectric Point: 4.5802

>NTDB_id=482301 J7T92_RS07805 WP_002951720.1 1488303..1489088(-) (codY) [Streptococcus thermophilus strain S24747]
MANLLDKTRKITSILQRSVDSLEGDLPYNNMAAQLADIIDCNAAIVNGGGALLGFAMKYKTNNDRVEKFFKAKQLPEEYI
RGISRVYDTQENIGIDSDLTIFPVELKDDFPDGLTTIAPIYGGGMRLGSFIIWRNDHDFVDDDLILVEIASTVVGLQLLH
LQTENLEETIRKQTAINMAINTLSYSEIKAVSAILNELDGLEGRLTASVIADRIGITRSVIVNALRKLESAGIIESRSLG
MKGTYLKVLNEGIYDKLKEYE

Nucleotide

• Length: 786 bp

>NTDB_id=482301 J7T92_RS07805 WP_002951720.1 1488303..1489088(-) (codY) [Streptococcus thermophilus strain S24747]
ATGGCAAATTTGCTTGATAAAACACGTAAAATTACTTCTATCTTGCAACGCTCAGTAGATAGTTTGGAAGGAGATCTTCC
ATACAACAACATGGCTGCTCAGTTGGCAGATATTATTGATTGTAATGCTGCTATTGTAAATGGTGGAGGTGCTCTCCTTG
GTTTTGCTATGAAATACAAAACCAACAATGACCGTGTGGAAAAGTTTTTTAAAGCTAAACAACTTCCAGAGGAATACATA
CGTGGTATCAGCCGTGTTTATGATACTCAAGAAAATATCGGTATTGACAGTGACTTGACCATCTTCCCAGTGGAATTAAA
AGATGATTTCCCTGACGGTTTGACTACAATTGCACCAATCTATGGTGGTGGTATGCGTCTTGGTTCTTTCATTATTTGGC
GTAACGACCATGATTTTGTGGACGACGACCTTATCTTGGTTGAGATTGCATCTACAGTAGTTGGTTTGCAATTGTTGCAT
CTTCAAACAGAAAACTTGGAAGAAACGATTCGTAAACAAACAGCTATTAATATGGCTATTAATACCTTGTCTTACTCAGA
AATCAAGGCAGTTTCAGCTATCTTGAATGAGTTGGACGGTTTAGAAGGTCGTTTGACAGCCTCTGTTATCGCGGACCGTA
TCGGAATTACTCGTTCTGTTATTGTTAATGCTCTTCGTAAATTAGAATCAGCTGGTATTATTGAAAGTCGTTCGCTTGGT
ATGAAAGGCACTTACCTTAAAGTCCTTAACGAAGGTATCTACGACAAATTGAAAGAATACGAATAA

Domains

Predicted by InterProScan.

• CodY GAF-like domain (CodY) (3-182)

• CodY helix-turn-helix domain (HTH_CodY) (201-261)

3D structure

• AlphaFold DB: Q5M305

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
codY	Lactococcus lactis subsp. lactis strain DGCC12653	64.591	98.467	0.636
codY	Bacillus subtilis subsp. subtilis str. 168	53.036	94.636	0.502