Detailed information NTG0482098

Bioinformatically predicted

Overview

• Name: codY
• Type: Regulator
• Locus tag: J7T78_RS08065
• Genome accession: NZ_CP072427
• Coordinates: 1564134..1564919 (-)
• Length: 261 a.a.
• NCBI ID: WP_002951720.1
• Uniprot ID: Q5M305
• Organism: Streptococcus thermophilus strain S24750
• Function: repress the expression of comX (predicted from homology) Competence regulation

Genomic Context

Location: 1559134..1569919

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
J7T78_RS08030 (J7T78_07970)	gatC	1559195..1559497 (-)	303	WP_002884769.1	Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC	-
J7T78_RS08035 (J7T78_07975)	-	1559672..1559869 (-)	198	WP_242681688.1	glycosyltransferase	-
J7T78_RS08040	-	1559829..1559993 (-)	165	WP_242681665.1	glycosyltransferase	-
J7T78_RS08045 (J7T78_07985)	-	1560430..1561874 (-)	1445	Protein_1545	6-phospho-beta-glucosidase	-
J7T78_RS08050 (J7T78_07990)	msrA	1562027..1562536 (-)	510	WP_041827375.1	peptide-methionine (S)-S-oxide reductase MsrA	-
J7T78_RS08055 (J7T78_07995)	-	1562548..1563396 (-)	849	Protein_1547	MetQ/NlpA family ABC transporter substrate-binding protein	-
J7T78_RS08060 (J7T78_08000)	-	1563520..1564071 (-)	552	WP_002946999.1	cysteine hydrolase family protein	-
J7T78_RS08065 (J7T78_08005)	codY	1564134..1564919 (-)	786	WP_002951720.1	GTP-sensing pleiotropic transcriptional regulator CodY	Regulator
J7T78_RS08070 (J7T78_08010)	-	1565179..1566393 (-)	1215	WP_002951721.1	pyridoxal phosphate-dependent aminotransferase	-
J7T78_RS08075 (J7T78_08015)	-	1566748..1567200 (+)	453	WP_002946987.1	universal stress protein	-
J7T78_RS08080 (J7T78_08020)	-	1567380..1567951 (+)	572	Protein_1552	IS30 family transposase	-
J7T78_RS08085 (J7T78_08025)	-	1568023..1568196 (-)	174	WP_011681546.1	hypothetical protein	-
J7T78_RS08090 (J7T78_08030)	-	1568257..1568631 (-)	375	WP_011681547.1	membrane protein	-
J7T78_RS08095 (J7T78_08035)	pflA	1568843..1569643 (-)	801	WP_071417327.1	pyruvate formate-lyase-activating protein	-

Sequence

Protein

• Length: 261 a.a.
• Molecular weight: 28919.13 Da
• Isoelectric Point: 4.5802

>NTDB_id=482098 J7T78_RS08065 WP_002951720.1 1564134..1564919(-) (codY) [Streptococcus thermophilus strain S24750]
MANLLDKTRKITSILQRSVDSLEGDLPYNNMAAQLADIIDCNAAIVNGGGALLGFAMKYKTNNDRVEKFFKAKQLPEEYI
RGISRVYDTQENIGIDSDLTIFPVELKDDFPDGLTTIAPIYGGGMRLGSFIIWRNDHDFVDDDLILVEIASTVVGLQLLH
LQTENLEETIRKQTAINMAINTLSYSEIKAVSAILNELDGLEGRLTASVIADRIGITRSVIVNALRKLESAGIIESRSLG
MKGTYLKVLNEGIYDKLKEYE

Nucleotide

• Length: 786 bp

>NTDB_id=482098 J7T78_RS08065 WP_002951720.1 1564134..1564919(-) (codY) [Streptococcus thermophilus strain S24750]
ATGGCAAATTTGCTTGATAAAACACGTAAAATTACTTCTATCTTGCAACGCTCAGTAGATAGTTTGGAAGGAGATCTTCC
ATACAACAACATGGCTGCTCAGTTGGCAGATATTATTGATTGTAATGCTGCTATTGTAAATGGTGGAGGTGCTCTCCTTG
GTTTTGCTATGAAATACAAAACCAACAATGACCGTGTGGAAAAGTTTTTTAAAGCTAAACAACTTCCAGAGGAATACATA
CGTGGTATCAGCCGTGTTTATGATACTCAAGAAAATATCGGTATTGACAGTGACTTGACCATCTTCCCAGTGGAATTAAA
AGATGATTTCCCTGACGGTTTGACTACAATTGCACCAATCTATGGTGGTGGTATGCGTCTTGGTTCTTTCATTATTTGGC
GTAACGACCATGATTTTGTGGACGACGACCTTATCTTGGTTGAGATTGCATCTACAGTAGTTGGTTTGCAATTGTTGCAT
CTTCAAACAGAAAACTTGGAAGAAACGATTCGTAAACAAACAGCTATTAATATGGCTATTAATACCTTGTCTTACTCAGA
AATCAAGGCAGTTTCAGCTATCTTGAATGAGTTGGACGGTTTAGAAGGTCGTTTGACAGCCTCTGTTATCGCGGACCGTA
TCGGAATTACTCGTTCTGTTATTGTTAATGCTCTTCGTAAATTAGAATCAGCTGGTATTATTGAAAGTCGTTCGCTTGGT
ATGAAAGGCACTTACCTTAAAGTCCTTAACGAAGGTATCTACGACAAATTGAAAGAATACGAATAA

Domains

Predicted by InterProScan.

• CodY GAF-like domain (CodY) (3-182)

• CodY helix-turn-helix domain (HTH_CodY) (201-261)

3D structure

• AlphaFold DB: Q5M305

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
codY	Lactococcus lactis subsp. lactis strain DGCC12653	64.591	98.467	0.636
codY	Bacillus subtilis subsp. subtilis str. 168	53.036	94.636	0.502