Detailed information    

insolico Bioinformatically predicted

Overview

Name   codY   Type   Regulator
Locus tag   J5Z97_RS07410 Genome accession   NZ_CP072112
Coordinates   1462552..1463334 (-) Length   260 a.a.
NCBI ID   WP_002983278.1    Uniprot ID   A2RCV3
Organism   Streptococcus pyogenes strain M08500     
Function   repress the expression of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1457552..1468334
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  J5Z97_RS07385 (J5Z97_07385) gatB 1457650..1459089 (-) 1440 WP_011054945.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatB -
  J5Z97_RS07390 (J5Z97_07390) gatA 1459089..1460555 (-) 1467 WP_011018163.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA -
  J5Z97_RS07395 (J5Z97_07395) gatC 1460555..1460857 (-) 303 WP_032467222.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC -
  J5Z97_RS07400 (J5Z97_07400) - 1461089..1461352 (-) 264 WP_002983284.1 putative PEP-binding protein -
  J5Z97_RS07405 (J5Z97_07405) - 1461851..1462405 (-) 555 WP_002983281.1 isochorismatase family cysteine hydrolase -
  J5Z97_RS07410 (J5Z97_07410) codY 1462552..1463334 (-) 783 WP_002983278.1 GTP-sensing pleiotropic transcriptional regulator CodY Regulator
  J5Z97_RS07415 (J5Z97_07415) - 1463552..1464766 (-) 1215 WP_011184883.1 pyridoxal phosphate-dependent aminotransferase -
  J5Z97_RS07420 (J5Z97_07420) - 1464997..1465449 (+) 453 WP_002992571.1 universal stress protein -
  J5Z97_RS07425 (J5Z97_07425) - 1465572..1466960 (-) 1389 WP_002992572.1 Cof-type HAD-IIB family hydrolase -
  J5Z97_RS07430 (J5Z97_07430) - 1467032..1467997 (+) 966 WP_002983258.1 asparaginase -

Sequence

Protein


Download         Length: 260 a.a.        Molecular weight: 28633.76 Da        Isoelectric Point: 4.5611

>NTDB_id=480571 J5Z97_RS07410 WP_002983278.1 1462552..1463334(-) (codY) [Streptococcus pyogenes strain M08500]
MPNLLEKTRKITSILQRSVDSLETELPYNTMASRLADIIDCNACIINGGGTLLGYAMKYKTNTDRVEEFFEAKQFPDTYV
KAASRVYDTEANLSVENELTIFPVESKDTYPGGLTTIAPIYGGGMRLGSLIIWRNDNEFSDDDLILVEISSTVVGIQLLN
LQTENLEDTIRKQTAVNMAINTLSYSEMKAVAAILGELDGNEGRLTASVIADRIGITRSVIVNALRKLESAGIIESRSLG
MKGTYLKVINEGIFAKLKEF

Nucleotide


Download         Length: 783 bp        

>NTDB_id=480571 J5Z97_RS07410 WP_002983278.1 1462552..1463334(-) (codY) [Streptococcus pyogenes strain M08500]
ATGCCTAACTTATTAGAAAAAACTCGTAAAATCACATCTATTTTGCAGCGTTCCGTAGATAGCCTAGAAACAGAATTACC
GTATAACACAATGGCATCTCGCCTAGCAGATATCATTGACTGCAATGCTTGTATTATCAATGGCGGCGGCACACTGCTTG
GTTATGCCATGAAATATAAAACTAACACTGATCGTGTTGAGGAATTTTTTGAAGCTAAACAATTTCCAGATACTTATGTA
AAGGCTGCTAGCCGAGTTTACGATACAGAAGCTAACCTTTCTGTCGAAAATGAGTTGACTATATTCCCTGTTGAGTCTAA
AGACACTTATCCAGGAGGTCTAACGACTATTGCGCCGATTTATGGTGGAGGGATGCGCCTTGGATCACTCATTATCTGGC
GTAATGACAATGAGTTTAGTGATGATGATTTGATTTTGGTTGAGATCTCAAGTACTGTTGTGGGGATTCAACTATTAAAT
CTTCAGACAGAAAACTTAGAAGACACCATCCGTAAACAAACAGCGGTCAACATGGCAATTAATACGCTTTCTTATTCAGA
AATGAAAGCTGTTGCAGCAATTCTTGGAGAGTTAGATGGTAATGAAGGACGATTGACAGCTTCTGTTATTGCTGATCGTA
TTGGTATTACCCGTTCTGTTATTGTCAATGCTCTGCGTAAACTAGAAAGTGCAGGGATTATTGAAAGTCGTTCTCTTGGT
ATGAAAGGGACATACCTCAAAGTTATCAACGAAGGTATTTTTGCTAAATTAAAAGAATTTTAA

Domains

Predicted by InterProScan.

CodY helix-turn-helix domain (HTH_CodY)

(202-260)

CodY GAF-like domain (CodY)

(3-182)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A2RCV3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  codY Lactococcus lactis subsp. lactis strain DGCC12653

66.148

98.846

0.654
  codY Bacillus subtilis subsp. subtilis str. 168

51.373

98.077

0.504