Detailed information NTG0480127

Bioinformatically predicted

Overview

• Name: comB4
• Type: Machinery gene
• Locus tag: J5D22_RS04900
• Genome accession: NZ_CP071977
• Coordinates: 1059524..1062100 (-)
• Length: 858 a.a.
• NCBI ID: WP_209505418.1
• Uniprot ID: -
• Organism: Helicobacter pylori strain MT5105
• Function: transformation-associated type IV transport system (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1054524..1067100

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
J5D22_RS04885 (J5D22_04885)	-	1055402..1056609 (-)	1208	Protein_975	DNA type IV secretion system protein ComB10	-
J5D22_RS04890 (J5D22_04890)	-	1056606..1058261 (-)	1656	WP_000617227.1	TrbG/VirB9 family P-type conjugative transfer protein	-
J5D22_RS04895 (J5D22_04895)	-	1058258..1059394 (-)	1137	WP_209505416.1	VirB8/TrbF family protein	-
J5D22_RS07940	-	1059387..1059527 (-)	141	WP_000789929.1	hypothetical protein	-
J5D22_RS04900 (J5D22_04900)	comB4	1059524..1062100 (-)	2577	WP_209505418.1	VirB4 family type IV secretion/conjugal transfer ATPase	Machinery gene
J5D22_RS04905 (J5D22_04905)	-	1062100..1062336 (-)	237	WP_001168532.1	hypothetical protein	-
J5D22_RS04910 (J5D22_04910)	comB3	1062348..1062611 (-)	264	WP_001177718.1	hypothetical protein	Machinery gene
J5D22_RS04915 (J5D22_04915)	comB2	1062623..1062907 (-)	285	WP_000413637.1	TrbC/VirB2 family protein	Machinery gene
J5D22_RS04920 (J5D22_04920)	-	1062895..1063383 (-)	489	WP_209505420.1	hypothetical protein	-
J5D22_RS04925 (J5D22_04925)	-	1063376..1063606 (-)	231	WP_000189082.1	hypothetical protein	-
J5D22_RS04930 (J5D22_04930)	-	1063609..1064397 (-)	789	WP_001140576.1	hypothetical protein	-
J5D22_RS07945	-	1064473..1065545 (+)	1073	Protein_986	type IV secretion system protein	-
J5D22_RS04945 (J5D22_04945)	-	1065617..1066300 (+)	684	WP_209505422.1	CAAX protease	-

Sequence

Protein

• Length: 858 a.a.
• Molecular weight: 98531.63 Da
• Isoelectric Point: 8.7641

>NTDB_id=480127 J5D22_RS04900 WP_209505418.1 1059524..1062100(-) (comB4) [Helicobacter pylori strain MT5105]
MLESALKYCKEKAIDLLAGFVPKTYSMAQECNILGLYDDTFIITKQENLVGIISLQGLSYSNLMQKDLEGYFDTRQNVLN
TISKDIQLRIVAKRRKEFINQSPNIDNIYAKAIITQFESKEIYKTEYFLVFETITSNVKSFFEKKKLEMTTSINEELEEG
SKEDKQENENSSNETHSNTSSKKDKKNKFKKKITFSATSKRALLIQTIERVKNALKEFKPTLLNSKEVLNFYAEYINGKY
IAFNPKLKRLSDSYIASNVHFKKDYFVIEFQNQNTFCACVGIKAYESEEISSLPISTLLHTQIELDLIFHIRSLGQFESL
NFLKTKKKLTLSKIVKADIDNYIELVQANRLSMQECALNLVIRAKSKAKLDKSLKEILSLLNNAGLGSVTETIGLKPSYF
SFFPNNANINPRMRNQTSQVIASLILFEKNNTGFRANSWGDMPLSVFKNLDHSPYLFNFHNQEVKHKGVLAHNVARVVGH
TMIIGATGAGKTTLISYLMMSALKYSNIDILALDRLNGLYSFTKYFDGIYNQGENFHINPFSLEDSATNRAFLLHFYAQM
AKVDSYDDHKDKVEDRTALLNAIDTMYRNYNDEVKQAKFSNQELPLPFDLKEFVNAIVKTNTDILDSSFEDYLKSSLFSS
RMDSLDFKTRISTINTDSILHNDDDAGLLAYYVFHKMIDRALKINRGFLCFIDEFKSYAQNEMMNKKINEIITQARKANG
VIVLALQDINQLSEVRNAQSFIKNMGQLILYPQRNIDTKDLNDKFGIRLSDTEKHFLENTAVNEYKVLLKNMNDGSSNII
DVSLSSLGNYLQIFSSNSSMVEHIDNLIKHYPKTWREVFVSNKHENFDDKKHLEKVLK

Nucleotide

• Length: 2577 bp

>NTDB_id=480127 J5D22_RS04900 WP_209505418.1 1059524..1062100(-) (comB4) [Helicobacter pylori strain MT5105]
ATGTTAGAAAGCGCCCTAAAATATTGCAAGGAAAAAGCCATAGACCTTTTAGCAGGGTTTGTGCCAAAAACCTATTCTAT
GGCACAGGAGTGCAATATTTTAGGCTTGTATGATGATACTTTCATTATTACCAAACAAGAAAATCTAGTAGGCATTATAT
CCTTACAAGGACTAAGCTATTCTAATTTAATGCAAAAAGACTTAGAGGGCTATTTTGATACTAGACAAAATGTTCTCAAC
ACCATTAGTAAAGACATTCAATTAAGAATTGTGGCTAAAAGGCGTAAGGAATTTATCAATCAAAGTCCAAATATTGACAA
TATTTATGCCAAAGCTATTATCACACAATTTGAAAGCAAGGAAATCTATAAAACAGAGTATTTTTTAGTGTTTGAAACTA
TCACTTCTAATGTCAAGTCTTTCTTTGAAAAAAAGAAATTGGAAATGACTACTTCAATTAATGAAGAGTTAGAAGAAGGC
TCTAAAGAAGATAAACAAGAGAATGAAAATAGCTCCAATGAGACCCATTCAAACACAAGCTCTAAAAAAGACAAGAAAAA
CAAGTTCAAAAAAAAGATAACCTTTAGCGCCACAAGTAAAAGAGCCTTACTCATTCAAACCATAGAAAGAGTAAAAAACG
CTCTTAAAGAATTTAAACCCACTTTACTAAATTCTAAAGAAGTATTAAATTTCTACGCAGAATACATCAATGGCAAATAC
ATCGCCTTTAATCCTAAATTAAAGCGATTAAGCGATAGCTATATTGCATCTAATGTGCATTTTAAGAAAGATTACTTTGT
CATTGAATTTCAAAATCAAAACACCTTTTGTGCGTGTGTGGGGATTAAGGCTTATGAGAGCGAAGAAATTTCTTCGCTCC
CTATATCTACTCTTTTACACACCCAAATTGAACTAGATTTAATCTTTCATATCCGCTCTTTAGGGCAATTTGAAAGCCTG
AATTTTTTAAAAACTAAGAAAAAGCTCACGCTTTCTAAAATAGTAAAAGCTGATATTGATAATTATATAGAATTGGTGCA
AGCCAATCGTTTGAGTATGCAAGAGTGCGCCTTAAACTTAGTTATAAGAGCTAAGAGCAAAGCCAAATTAGACAAATCTT
TAAAAGAGATTTTATCCTTGCTTAATAATGCTGGACTAGGCAGTGTTACAGAAACCATAGGGCTAAAACCCTCTTATTTT
TCATTCTTCCCTAATAATGCAAACATTAACCCTAGAATGAGAAATCAAACTTCCCAAGTGATAGCCTCTTTAATCTTGTT
TGAAAAAAATAATACAGGTTTTAGGGCAAATTCTTGGGGTGATATGCCTCTATCTGTGTTTAAGAACCTAGACCATAGCC
CTTATTTGTTTAATTTTCATAATCAAGAAGTCAAACATAAGGGCGTGTTAGCCCACAATGTCGCACGAGTAGTGGGACAT
ACCATGATTATAGGAGCAACAGGTGCTGGTAAAACCACACTCATTAGCTATTTGATGATGAGTGCCTTAAAATATTCTAA
CATTGATATTTTAGCTCTTGATAGACTAAATGGTTTGTATTCCTTTACCAAGTATTTTGATGGGATTTATAATCAAGGCG
AAAACTTTCATATTAACCCTTTTTCATTAGAAGATAGCGCAACTAATAGAGCCTTCTTATTGCATTTTTATGCCCAAATG
GCAAAAGTGGATAGTTATGATGACCATAAGGATAAAGTAGAAGATAGAACAGCCCTTTTAAATGCTATTGATACGATGTA
TAGAAATTATAACGATGAAGTCAAACAAGCCAAATTTAGCAACCAAGAATTACCCCTTCCTTTTGATTTAAAAGAGTTTG
TCAATGCCATTGTTAAAACCAATACAGACATTTTAGATAGTAGTTTTGAAGACTATTTAAAATCTTCCTTATTTTCTAGC
CGAATGGATAGTCTAGATTTTAAAACTCGTATTAGCACCATAAATACCGATAGCATTTTACATAATGATGATGACGCTGG
GCTTTTAGCCTACTATGTCTTTCATAAGATGATTGACAGAGCCTTAAAAATCAATCGTGGGTTTTTATGCTTTATTGATG
AGTTTAAGTCTTACGCTCAAAATGAAATGATGAATAAAAAAATCAATGAAATCATTACTCAAGCTAGAAAGGCTAATGGG
GTGATTGTTCTAGCCTTACAAGACATTAACCAACTAAGCGAAGTGAGAAACGCTCAAAGCTTTATAAAAAATATGGGGCA
ATTGATTTTGTATCCCCAAAGAAATATTGATACCAAAGATTTAAACGATAAATTTGGCATTAGACTAAGCGATACAGAAA
AACATTTTTTAGAAAACACCGCCGTTAATGAATACAAAGTCTTACTCAAAAACATGAATGATGGCTCATCTAACATTATA
GATGTGAGCCTAAGTTCTTTGGGTAATTACCTACAAATCTTTAGCTCTAATTCTAGCATGGTAGAACACATTGATAATCT
CATTAAGCATTACCCTAAAACTTGGCGAGAAGTCTTTGTGAGTAACAAACACGAAAATTTTGATGACAAAAAACACTTAG
AAAAGGTGCTTAAATGA

Domains

Predicted by InterProScan.

• CagE, TrbE, VirB family, component of type IV transporter system (CagE_TrbE_VirB) (214-412)

• FtsK/SpoIIIE family (FtsK_SpoIIIE) (437-505)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comB4	Helicobacter pylori 26695	46.786	97.902	0.458