Detailed information NTG0479478

Bioinformatically predicted

Overview

• Name: endA
• Type: Machinery gene
• Locus tag: IBC08_RS05435
• Genome accession: NZ_CP061019
• Coordinates: 1040839..1041720 (-)
• Length: 293 a.a.
• NCBI ID: WP_011681210.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus strain 24853
• Function: cleavage of dsDNA into ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1035839..1046720

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
IBC08_RS05410 (IBC08_05400)	vicR	1036543..1037250 (-)	708	WP_011681206.1	response regulator YycF	Regulator
IBC08_RS05415 (IBC08_05405)	-	1037777..1038544 (+)	768	WP_011681207.1	amino acid ABC transporter ATP-binding protein	-
IBC08_RS05420 (IBC08_05410)	-	1038556..1039389 (+)	834	WP_014608373.1	transporter substrate-binding domain-containing protein	-
IBC08_RS05425 (IBC08_05415)	-	1039407..1040105 (+)	699	WP_014608374.1	amino acid ABC transporter permease	-
IBC08_RS05430 (IBC08_05420)	-	1040117..1040767 (+)	651	WP_014608375.1	amino acid ABC transporter permease	-
IBC08_RS05435 (IBC08_05425)	endA	1040839..1041720 (-)	882	WP_011681210.1	DNA/RNA non-specific endonuclease	Machinery gene
IBC08_RS05440 (IBC08_05430)	-	1041782..1041970 (-)	189	WP_011226090.1	DNA-directed RNA polymerase subunit beta	-
IBC08_RS05445 (IBC08_05435)	murA	1041972..1043243 (-)	1272	WP_014608377.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
IBC08_RS05450 (IBC08_05440)	-	1043313..1043549 (-)	237	WP_002946959.1	DUF1146 family protein	-
IBC08_RS05455 (IBC08_05445)	galE	1043737..1044750 (-)	1014	WP_011681212.1	UDP-glucose 4-epimerase GalE	-
IBC08_RS05460 (IBC08_05450)	-	1044765..1045220 (-)	456	WP_024009932.1	DUF4832 domain-containing protein	-

Sequence

Protein

• Length: 293 a.a.
• Molecular weight: 31773.50 Da
• Isoelectric Point: 10.1789

>NTDB_id=479478 IBC08_RS05435 WP_011681210.1 1040839..1041720(-) (endA) [Streptococcus thermophilus strain 24853]
MAKRKTSLTNKQKRQLVTLIIAALIAVLGYLGTSNKLSPDNPIRQVASLVSGKSNKSIKSNGSTNSQSTPQEQLAETVMT
SSVKSQLGNSLEWNGAGAYIINRNKTNLNAKVSSQPYANNQVKTVQGQTVPTVANALLSKATRQYKNRQETGNGSTSWTP
AGWHQVQNLSGEYSHAVDRGHLLGYALIGGLKGFDASTSNPENIAVQTAWANQAYSDSSTGQNYYESLVRKALDKNKRVR
YRVTLIYEGENLIPSGTHLEAKSADGSLEFNVFVPNVQEGITLDYYSGKVTVN

Nucleotide

• Length: 882 bp

>NTDB_id=479478 IBC08_RS05435 WP_011681210.1 1040839..1041720(-) (endA) [Streptococcus thermophilus strain 24853]
ATGGCAAAAAGAAAGACATCTTTGACAAATAAACAGAAACGTCAGTTAGTCACATTAATAATAGCAGCTTTGATAGCTGT
TTTAGGTTACCTAGGAACCAGTAACAAGCTCTCGCCTGATAATCCTATCAGACAAGTAGCAAGCCTAGTTTCAGGGAAAT
CTAACAAATCCATTAAATCTAATGGTTCAACAAATAGTCAGTCTACACCACAAGAGCAGCTTGCTGAGACAGTAATGACT
AGTTCAGTCAAAAGCCAACTGGGTAATTCCTTAGAATGGAATGGAGCTGGGGCCTACATTATTAATAGAAATAAGACGAA
TCTAAATGCTAAGGTATCAAGCCAACCCTATGCTAATAACCAAGTCAAAACGGTTCAAGGACAAACTGTTCCTACAGTTG
CTAATGCCTTATTAAGTAAAGCAACTAGACAGTACAAAAATCGTCAAGAAACAGGGAATGGTTCAACCTCTTGGACACCA
GCTGGATGGCACCAGGTTCAAAATTTATCAGGAGAGTATAGCCATGCCGTAGATAGAGGCCATTTGCTAGGTTATGCACT
GATAGGTGGTTTGAAAGGATTTGATGCCTCGACTTCAAATCCAGAGAATATTGCTGTTCAAACTGCTTGGGCAAATCAAG
CATATAGCGATAGTTCTACAGGCCAAAACTATTATGAAAGCCTAGTACGAAAAGCTCTGGATAAAAACAAACGTGTTCGT
TATCGTGTGACCCTGATTTATGAAGGAGAGAATCTCATTCCATCAGGAACACATCTTGAAGCTAAGTCAGCAGACGGCTC
ACTTGAGTTTAATGTCTTTGTTCCAAATGTACAAGAGGGAATTACACTAGATTACTATTCAGGAAAAGTAACGGTGAATT
GA

Domains

Predicted by InterproScan.

• DNA/RNA non-specific endonuclease (Endonuclease_NS) (101-266)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
endA	Streptococcus pneumoniae Rx1	72.803	81.57	0.594
endA	Streptococcus pneumoniae D39	72.803	81.57	0.594
endA	Streptococcus pneumoniae R6	72.803	81.57	0.594
endA	Streptococcus pneumoniae TIGR4	72.803	81.57	0.594