Detailed information    

insolico Bioinformatically predicted

Overview

Name   mutS/mutS2   Type   Machinery gene
Locus tag   SPN994039_RS02075 Genome accession   NC_021005
Coordinates   381306..383642 (+) Length   778 a.a.
NCBI ID   WP_001035034.1    Uniprot ID   -
Organism   Streptococcus pneumoniae SPN994039     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 376306..388642
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SPN994039_RS02055 (SPN994039_03850) lepB 378769..379383 (-) 615 WP_001083986.1 signal peptidase I -
  SPN994039_RS02060 (SPN994039_03860) rnhC 379387..380268 (-) 882 WP_000146855.1 ribonuclease HIII -
  SPN994039_RS02065 (SPN994039_03870) zapA 380355..380657 (+) 303 WP_000002019.1 cell division protein ZapA -
  SPN994039_RS02070 (SPN994039_03880) - 380654..381202 (+) 549 WP_000622953.1 CvpA family protein -
  SPN994039_RS02075 (SPN994039_03890) mutS/mutS2 381306..383642 (+) 2337 WP_001035034.1 endonuclease MutS2 Machinery gene
  SPN994039_RS02080 (SPN994039_03900) - 383985..385307 (+) 1323 WP_000891497.1 sodium:alanine symporter family protein -
  SPN994039_RS02085 (SPN994039_03910) - 385525..386073 (+) 549 WP_000206761.1 carboxymuconolactone decarboxylase family protein -
  SPN994039_RS02090 (SPN994039_03920) - 386183..387082 (+) 900 WP_000735956.1 TDT family transporter -
  SPN994039_RS02095 (SPN994039_03930) serS 387107..388381 (-) 1275 WP_000884256.1 serine--tRNA ligase -

Sequence

Protein


Download         Length: 778 a.a.        Molecular weight: 87639.61 Da        Isoelectric Point: 6.8352

>NTDB_id=47787 SPN994039_RS02075 WP_001035034.1 381306..383642(+) (mutS/mutS2) [Streptococcus pneumoniae SPN994039]
MNKKILETLEFDKVKALFEPHLLTEQGLEQLRQLAPTAKADKIKQAFAEMKEMQALFVEQPHFTILSTKEIAGVCKRLEM
GADLNIEEFLLLKRVLLTSRELQSFYANLENVSLEELALWFEKLHDFPQLQGNLQAFNDAGFIENFASEELARIRRKIHD
SESQVRDVLQDLLKQKAQMLTEGIVASRNGRQVLPVKNTYRNKIAGVVHDISASGNTVYIEPREVVKLSEEIASLRADER
YEMLRILQEISERVRPHAAEIANDAWIIGHLDLIRAKVRFIQERQAVVPQLSENQEIQLLHVCHPLVKNAVANDVYFGQD
LTAIVITGPNTGGKTIMLKTLGLTQVMAQSGLPILADKGSRVGIFEEIFADIGDEQSIEQSLSTFSSHMTNIVDILGKVN
QHSLLLLDELGAGTDPQEGAALAMAILEDLRLRQIKTMATTHYPELKAYGIETAFVQNASMEFDTATLRPTYRFMQGVPG
RSNAFEIAKRLGLSEVIVGDASQQIDQDNDVNRIIEQLEEQTLESRKRLDNIREVEQENLKMNRVLKKLYNELNREKETE
LNKAREQAAEIVDMALSESDQILKNLHSKSQLKPHEIIEAKAKLKKLAPEKVDLSKNKVLQKAKKKRAPKVGDDIVVLSY
GQRGTLTSQLKDGRWEAQVGLIKMTLEEKEFDLVQAQQEKPVKKKQVNVVKRTSGRGPQARLDLRGKRYEEAMNELDTFI
DQALLNNMAQVDIIHGIGTGVIREGVTKYLQRNKHVKSFGYAPQNAGGSGATIVTFKG

Nucleotide


Download         Length: 2337 bp        

>NTDB_id=47787 SPN994039_RS02075 WP_001035034.1 381306..383642(+) (mutS/mutS2) [Streptococcus pneumoniae SPN994039]
ATGAATAAGAAAATATTAGAAACATTAGAGTTCGATAAGGTCAAGGCCTTGTTTGAGCCTCATTTGTTGACCGAGCAGGG
CTTGGAGCAATTGAGACAGCTGGCTCCGACTGCCAAAGCAGATAAAATCAAACAGGCTTTTGCTGAGATGAAAGAAATGC
AGGCTCTTTTCGTCGAGCAACCGCATTTTACTATTCTCTCAACTAAGGAAATTGCAGGAGTCTGCAAGAGGTTGGAGATG
GGAGCGGATCTCAATATCGAGGAGTTCCTACTCTTGAAACGCGTGCTTCTTACCAGCCGAGAACTTCAAAGTTTTTACGC
CAATCTGGAAAATGTCAGCTTGGAAGAATTAGCCCTTTGGTTTGAGAAATTACATGATTTTCCGCAATTACAAGGAAATC
TTCAGGCCTTTAATGATGCGGGTTTCATTGAAAATTTTGCCAGTGAAGAATTGGCGCGAATCCGTCGAAAAATACATGAT
AGCGAGAGTCAGGTACGCGATGTTTTACAAGACTTGCTCAAGCAAAAAGCGCAGATGTTGACGGAAGGAATTGTTGCTAG
CAGAAATGGCCGTCAGGTTTTACCAGTCAAAAACACCTACCGCAATAAGATTGCAGGTGTCGTTCATGATATTTCTGCTA
GTGGAAACACCGTCTATATCGAACCACGTGAGGTAGTCAAACTGAGCGAAGAAATTGCTAGTCTGCGAGCAGATGAGCGC
TATGAAATGCTTCGCATTCTCCAAGAAATTTCTGAGCGTGTCCGCCCTCATGCGGCTGAGATTGCTAATGACGCTTGGAT
TATCGGTCATCTGGACTTGATTCGTGCCAAGGTTCGATTTATCCAAGAAAGACAAGCAGTCGTGCCTCAGCTGTCAGAAA
ATCAAGAGATTCAACTGCTCCATGTCTGCCATCCTTTGGTCAAAAATGCCGTCGCAAATGATGTCTATTTTGGTCAAGAT
TTAACAGCTATTGTCATTACAGGTCCCAATACAGGTGGGAAGACCATCATGCTCAAAACTCTGGGCTTGACACAGGTCAT
GGCCCAGTCAGGATTGCCGATTTTAGCAGACAAGGGAAGTCGTGTTGGTATTTTTGAAGAAATCTTTGCTGATATTGGAG
ATGAGCAGTCTATTGAGCAGAGCTTGTCTACCTTCTCTAGCCATATGACCAATATCGTGGATATTCTTGGCAAGGTCAAC
CAACATTCACTCTTACTTTTGGATGAGTTGGGGGCTGGTACTGATCCCCAAGAGGGAGCAGCCCTTGCCATGGCTATTCT
GGAGGACCTTCGCCTGCGTCAAATCAAGACCATGGCGACGACCCACTATCCAGAACTCAAGGCCTACGGTATTGAGACAG
CCTTTGTGCAAAATGCCAGTATGGAGTTTGATACTGCAACTCTTCGCCCGACCTATCGCTTTATGCAGGGTGTTCCTGGC
CGAAGTAATGCCTTTGAAATTGCCAAACGTCTAGGCCTATCTGAAGTTATCGTAGGAGATGCCAGTCAGCAGATCGATCA
GGACAATGACGTCAATCGTATCATTGAGCAACTAGAAGAGCAGACGCTGGAAAGCCGCAAACGCTTGGACAATATCCGTG
AGGTGGAGCAAGAAAATCTCAAGATGAACCGTGTGCTAAAAAAACTCTACAACGAGCTTAATCGTGAAAAGGAAACCGAG
CTTAACAAGGCGCGTGAACAGGCTGCTGAGATTGTGGATATGGCCCTAAGTGAAAGTGACCAGATTCTCAAAAATCTCCA
CAGTAAATCCCAACTCAAGCCCCACGAAATCATTGAAGCCAAAGCCAAGTTGAAAAAATTGGCTCCTGAAAAAGTGGACT
TGTCTAAAAACAAGGTCCTTCAAAAGGCCAAGAAAAAACGAGCTCCAAAGGTGGGAGATGATATCGTGGTTCTCAGTTAT
GGTCAGCGTGGTACCTTGACCAGTCAACTCAAGGACGGCCGCTGGGAAGCCCAAGTTGGCTTGATTAAGATGACCTTGGA
AGAGAAAGAGTTTGATCTTGTTCAAGCCCAGCAAGAAAAACCAGTCAAGAAGAAACAGGTCAATGTTGTGAAACGAACTT
CTGGGCGAGGACCTCAAGCTAGACTGGATCTTCGAGGCAAGCGCTATGAAGAAGCCATGAATGAGCTAGATACCTTCATC
GACCAAGCCTTGCTTAACAATATGGCTCAAGTTGATATCATCCATGGTATCGGAACAGGAGTCATCCGTGAAGGAGTTAC
CAAATACTTGCAAAGAAACAAACATGTCAAGAGTTTCGGCTATGCCCCACAAAATGCTGGAGGCAGTGGTGCGACTATTG
TCACTTTTAAAGGATAG

Domains

Predicted by InterProScan.

Smr domain (Smr)

(702-777)

MutS domain V (MutS_V)

(324-506)

MutS2 and Smr-associated SH3 domain (MSSS)

(631-670)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mutS/mutS2 Bacillus subtilis subsp. subtilis str. 168

40.582

100

0.413

Multiple sequence alignment