Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYH   Type   Machinery gene
Locus tag   LLH_RS11100 Genome accession   NC_017492
Coordinates   2143300..2144238 (-) Length   312 a.a.
NCBI ID   WP_011677085.1    Uniprot ID   -
Organism   Lactococcus cremoris subsp. cremoris A76     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
ICE 2124744..2174506 2143300..2144238 within 0


Gene organization within MGE regions


Location: 2124744..2174506
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LLH_RS10990 (llh_11505) - 2124744..2125925 (+) 1182 WP_011677065.1 site-specific integrase -
  LLH_RS10995 (llh_11510) - 2126138..2126764 (+) 627 WP_011677066.1 copper homeostasis protein CutC -
  LLH_RS11000 (llh_11515) - 2126797..2127816 (-) 1020 WP_011677067.1 ABC transporter permease -
  LLH_RS11005 (llh_11520) - 2127809..2128579 (-) 771 WP_011677068.1 ABC transporter ATP-binding protein -
  LLH_RS11010 (llh_11525) - 2128598..2130169 (-) 1572 WP_259285562.1 glycerophosphodiester phosphodiesterase -
  LLH_RS11015 (llh_11530) - 2130535..2131425 (+) 891 WP_014572485.1 IS982-like element IS982B family transposase -
  LLH_RS11020 (llh_11535) - 2131681..2132079 (+) 399 WP_011677070.1 HIT family protein -
  LLH_RS11025 (llh_11540) - 2132094..2132315 (+) 222 WP_014573251.1 hypothetical protein -
  LLH_RS11030 (llh_11545) - 2132327..2132671 (-) 345 WP_014573252.1 hypothetical protein -
  LLH_RS11035 (llh_11550) rplA 2132749..2133438 (-) 690 WP_011677073.1 50S ribosomal protein L1 -
  LLH_RS11040 (llh_11555) rplK 2133825..2134250 (-) 426 WP_011677074.1 50S ribosomal protein L11 -
  LLH_RS11045 (llh_11560) - 2134386..2135150 (-) 765 WP_011677075.1 ABC transporter permease -
  LLH_RS11050 (llh_11565) - 2135150..2136028 (-) 879 Protein_2134 ATP-binding cassette domain-containing protein -
  LLH_RS11055 (llh_11575) - 2136095..2136304 (-) 210 WP_011677077.1 YozE family protein -
  LLH_RS11060 (llh_11580) msrA 2136338..2136859 (-) 522 WP_011677078.1 peptide-methionine (S)-S-oxide reductase MsrA -
  LLH_RS11065 (llh_11585) - 2137034..2137891 (-) 858 WP_011677079.1 S1 RNA-binding domain-containing protein -
  LLH_RS11070 (llh_11590) - 2137936..2138394 (-) 459 Protein_2138 GNAT family N-acetyltransferase -
  LLH_RS11075 (llh_11595) frr 2138479..2139036 (-) 558 WP_011677081.1 ribosome recycling factor -
  LLH_RS11080 (llh_11600) pyrH 2139192..2139908 (-) 717 WP_004254608.1 UMP kinase -
  LLH_RS11085 (llh_11605) - 2139993..2140445 (-) 453 WP_011677082.1 hypothetical protein -
  LLH_RS11090 (llh_11615) - 2140575..2141762 (-) 1188 WP_014573258.1 acetate kinase -
  LLH_RS11095 (llh_11620) - 2141921..2143108 (-) 1188 WP_011677084.1 acetate kinase -
  LLH_RS11100 (llh_11625) comYH 2143300..2144238 (-) 939 WP_011677085.1 class I SAM-dependent methyltransferase Machinery gene
  LLH_RS11105 (llh_11630) - 2144326..2144577 (-) 252 WP_011677086.1 DUF3165 family protein -
  LLH_RS11110 (llh_11635) typA 2144678..2146510 (-) 1833 WP_031286284.1 translational GTPase TypA -
  LLH_RS11125 (llh_11650) - 2147996..2148595 (+) 600 Protein_2148 IS982 family transposase -
  LLH_RS11130 (llh_11655) - 2148656..2149114 (-) 459 WP_014573263.1 hypothetical protein -
  LLH_RS11135 (llh_11660) - 2149129..2149743 (-) 615 WP_014573264.1 hypothetical protein -
  LLH_RS11140 (llh_11670) - 2150083..2150811 (-) 729 WP_014573266.1 LytTR family transcriptional regulator DNA-binding domain-containing protein -
  LLH_RS11145 (llh_11675) - 2151004..2151225 (+) 222 WP_011677095.1 YqgQ family protein -
  LLH_RS11150 (llh_11680) - 2151259..2152230 (+) 972 WP_014573267.1 ROK family glucokinase -
  LLH_RS11155 (llh_11685) - 2152233..2152619 (+) 387 WP_011677097.1 rhodanese-like domain-containing protein -
  LLH_RS11160 (llh_11690) - 2152735..2153181 (-) 447 WP_011677098.1 DNA starvation/stationary phase protection protein -
  LLH_RS11165 (llh_11700) - 2153347..2154012 (+) 666 WP_014573269.1 A24 family peptidase -
  LLH_RS11170 (llh_11705) dinB 2153963..2155057 (-) 1095 WP_041168260.1 DNA polymerase IV -
  LLH_RS11175 (llh_11710) - 2155133..2155624 (-) 492 WP_014573271.1 prolyl-tRNA synthetase associated domain-containing protein -
  LLH_RS11180 (llh_11715) - 2155700..2157193 (-) 1494 WP_011677103.1 basic amino acid/polyamine antiporter -
  LLH_RS11185 (llh_11720) - 2157402..2158292 (-) 891 WP_014573272.1 IS982-like element IS982B family transposase -
  LLH_RS11190 (llh_11730) - 2158391..2159521 (-) 1131 Protein_2161 aminotransferase -
  LLH_RS11195 (llh_11735) arcC 2159785..2160729 (-) 945 WP_014573275.1 carbamate kinase -
  LLH_RS11200 (llh_11740) arcC 2160762..2161706 (-) 945 WP_014573276.1 carbamate kinase -
  LLH_RS11205 (llh_11745) - 2161724..2163304 (-) 1581 WP_014573277.1 basic amino acid/polyamine antiporter -
  LLH_RS11210 (llh_11750) argF 2163436..2164500 (-) 1065 WP_011677108.1 ornithine carbamoyltransferase -
  LLH_RS11215 (llh_11755) arcA 2164666..2165898 (-) 1233 WP_014573278.1 arginine deiminase -
  LLH_RS11220 (llh_11760) argS 2166199..2167893 (-) 1695 WP_011677109.1 arginine--tRNA ligase -
  LLH_RS11225 (llh_11765) argR 2167961..2168419 (+) 459 WP_004254487.1 arginine repressor -
  LLH_RS11230 (llh_11770) murC 2168579..2169910 (-) 1332 WP_014573279.1 UDP-N-acetylmuramate--L-alanine ligase -
  LLH_RS11235 (llh_11780) - 2170111..2170710 (-) 600 WP_011677112.1 hypothetical protein -
  LLH_RS11240 (llh_11785) - 2170927..2174031 (-) 3105 WP_011677113.1 DEAD/DEAH box helicase -

Sequence

Protein


Download         Length: 312 a.a.        Molecular weight: 34694.69 Da        Isoelectric Point: 4.3603

>NTDB_id=47704 LLH_RS11100 WP_011677085.1 2143300..2144238(-) (comYH) [Lactococcus cremoris subsp. cremoris A76]
MNMEKVAQGFELVVENITKLSEKLDTDFYDAFVEQNAAFLDGTDQGIVELSVNNDKLRQLNLSNKEWQKLFQFVLLKGSQ
VAPLQANHAMTPDAIGLIFNFIIEHLNKNSELRLIEFGSGMGNLAETLLVNLNKKVDYVGFEVDDLLLDLSASMAEIMGS
YAEFMQIDAVQKRLMEPADVVVSDLPIGFYPDDEVAKNFEVAATDGHTFAHHLLIEQSFNYLKDGAFAVFLAPEDLLTSV
QGPLLKEWISQHGSIMAVITLPSSLFNADAKAIYVLKKGPAAHATFAHPLSSLTDRESLEIFMEEFTKTVKL

Nucleotide


Download         Length: 939 bp        

>NTDB_id=47704 LLH_RS11100 WP_011677085.1 2143300..2144238(-) (comYH) [Lactococcus cremoris subsp. cremoris A76]
ATGAACATGGAAAAAGTGGCTCAAGGTTTTGAGCTGGTAGTTGAAAATATTACAAAATTATCTGAGAAATTAGATACAGA
TTTTTATGATGCTTTTGTGGAACAAAATGCTGCTTTTTTAGATGGTACTGACCAAGGAATTGTTGAGCTGTCAGTAAATA
ATGACAAACTCCGTCAGTTAAATTTATCAAATAAAGAATGGCAAAAACTTTTTCAATTTGTTTTATTAAAAGGTTCGCAA
GTTGCGCCTCTTCAGGCAAATCATGCCATGACTCCTGATGCAATTGGTCTAATTTTCAACTTTATCATTGAACATCTCAA
TAAAAATTCTGAACTTCGATTAATTGAGTTTGGTTCTGGTATGGGTAATCTTGCGGAAACATTGCTTGTTAATCTTAATA
AAAAAGTAGATTATGTTGGTTTTGAAGTCGATGATTTACTTTTAGATTTGTCAGCTTCAATGGCTGAAATCATGGGAAGC
TATGCCGAATTTATGCAAATTGATGCGGTTCAAAAACGGTTGATGGAGCCAGCTGATGTTGTTGTTAGTGATTTGCCAAT
CGGTTTTTATCCAGATGATGAAGTTGCGAAAAATTTTGAAGTCGCTGCTACTGATGGACACACCTTTGCACATCATTTGT
TGATTGAACAATCATTTAATTACTTGAAAGATGGTGCTTTTGCAGTTTTCTTAGCACCGGAGGATTTACTGACAAGTGTA
CAAGGACCACTTTTAAAAGAATGGATTAGTCAGCATGGAAGTATTATGGCGGTAATTACTTTACCAAGCTCACTTTTTAA
TGCTGATGCTAAAGCAATTTATGTCTTGAAAAAAGGGCCTGCTGCTCATGCGACCTTTGCTCATCCTTTGTCATCATTGA
CAGACAGAGAAAGTTTAGAAATCTTTATGGAAGAATTTACAAAAACTGTAAAGTTATAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYH Streptococcus mutans UA140

49.201

100

0.494
  comYH Streptococcus mutans UA159

48.882

100

0.49

Multiple sequence alignment