Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   J0O73_RS14395 Genome accession   NZ_CP071375
Coordinates   2970309..2970965 (-) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain E105     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2965309..2975965
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  J0O73_RS14365 (J0O73_14355) yecA 2966560..2967225 (-) 666 WP_000847882.1 UPF0149 family protein YecA -
  J0O73_RS14385 (J0O73_14375) pgsA 2967875..2968423 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  J0O73_RS14390 (J0O73_14380) uvrC 2968480..2970312 (-) 1833 WP_053884504.1 excinuclease ABC subunit UvrC Machinery gene
  J0O73_RS14395 (J0O73_14385) letA 2970309..2970965 (-) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  J0O73_RS27660 - 2971107..2971223 (+) 117 WP_001302039.1 hypothetical protein -
  J0O73_RS14400 (J0O73_14390) yecU 2971261..2971437 (+) 177 WP_000590344.1 protein YecU -
  J0O73_RS14405 (J0O73_14395) yecF 2971424..2971648 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  J0O73_RS14410 (J0O73_14400) sdiA 2971716..2972438 (-) 723 WP_053884505.1 transcriptional regulator SdiA -
  J0O73_RS14415 (J0O73_14405) tcyN 2972668..2973420 (-) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  J0O73_RS14420 (J0O73_14410) tcyL 2973417..2974085 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  J0O73_RS14425 (J0O73_14415) dcyD 2974100..2975086 (-) 987 WP_001128214.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=476772 J0O73_RS14395 WP_000611328.1 2970309..2970965(-) (letA) [Escherichia coli strain E105]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=476772 J0O73_RS14395 WP_000611328.1 2970309..2970965(-) (letA) [Escherichia coli strain E105]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGTCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATCCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATTGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACAAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482