Detailed information NTG0474154

Bioinformatically predicted

Overview

• Name: dprA/cilB/dalA
• Type: Machinery gene
• Locus tag: H6X75_RS05910
• Genome accession: NZ_CP060156
• Coordinates: 1185329..1186177 (-)
• Length: 282 a.a.
• NCBI ID: WP_000705303.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain PZ900700608
• Function: ssDNA binding; loading RecA onto ssDNA; competence shut-off (predicted from homology) DNA processing Competence regulation

Genomic Context

Location: 1180329..1191177

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H6X75_RS05895 (H6X75_05880)	-	1180728..1181087 (-)	360	WP_001237218.1	YbaN family protein	-
H6X75_RS05900 (H6X75_05885)	topA	1181193..1183280 (-)	2088	WP_000179652.1	type I DNA topoisomerase	-
H6X75_RS05905 (H6X75_05890)	-	1183447..1184490 (-)	1044	WP_001812957.1	TIGR00341 family protein	-
H6X75_RS05910 (H6X75_05895)	dprA/cilB/dalA	1185329..1186177 (-)	849	WP_000705303.1	DNA-processing protein DprA	Machinery gene
H6X75_RS05915 (H6X75_05900)	-	1186273..1186962 (-)	690	WP_000643972.1	sugar phosphate nucleotidyltransferase	-
H6X75_RS05920 (H6X75_05905)	-	1186974..1187852 (-)	879	WP_000837609.1	DMT family transporter	-
H6X75_RS05925 (H6X75_05910)	licA	1187842..1188711 (-)	870	WP_000411202.1	choline kinase LicA	-
H6X75_RS05930 (H6X75_05915)	-	1188728..1189750 (-)	1023	WP_000609892.1	ribitol-5-phosphate dehydrogenase	-
H6X75_RS05935 (H6X75_05920)	-	1189755..1190462 (-)	708	WP_000638499.1	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	-

Sequence

Protein

• Length: 282 a.a.
• Molecular weight: 31076.75 Da
• Isoelectric Point: 5.4047

>NTDB_id=474154 H6X75_RS05910 WP_000705303.1 1185329..1186177(-) (dprA/cilB/dalA) [Streptococcus pneumoniae strain PZ900700608]
MKITNYEIYKLKKSGLTNQQILKVLEYGENVDQELLLGDIADISGCRNPAVFMERYFQIDDAHLSKEFQKFPSFSILDDC
YPWDLSEIYDAPVLLFYKGNLDLLKFPKVAVVGSRACSKQGAKSVEKVIQGLENELVIVSGLAKGIDTAAHMAALQNGGK
TIAVIGTGLDVFYPKANKRLQDYIGNDHLVLSEYGPGEQPLKFHFPARNRIIAGLCRGVIVAEAKMRSGSLITCERAMEE
GRDVFAIPASILDGLSDGCHHLIQEGAKLVTSGQDVLAEFEF

Nucleotide

• Length: 849 bp

>NTDB_id=474154 H6X75_RS05910 WP_000705303.1 1185329..1186177(-) (dprA/cilB/dalA) [Streptococcus pneumoniae strain PZ900700608]
ATGAAAATCACAAACTATGAAATCTATAAGTTAAAAAAATCAGGTTTGACCAATCAACAGATTTTGAAAGTGCTAGAATA
CGGTGAAAATGTTGATCAGGAGCTTTTGTTGGGTGATATTGCAGATATATCAGGTTGCCGTAATCCAGCCGTTTTTATGG
AACGTTATTTTCAGATAGACGATGCGCATTTGTCGAAAGAGTTTCAAAAATTTCCATCTTTCTCTATTTTAGATGACTGT
TATCCTTGGGATTTGAGTGAAATATATGATGCGCCTGTACTTTTATTTTACAAGGGAAATCTTGACCTCCTGAAATTCCC
GAAGGTAGCGGTCGTGGGCAGTCGTGCTTGTAGCAAACAGGGAGCTAAATCAGTTGAAAAAGTCATTCAAGGCTTGGAAA
ATGAACTGGTTATTGTCAGTGGTCTGGCCAAGGGCATTGACACAGCAGCTCATATGGCAGCTCTTCAGAATGGCGGAAAA
ACCATTGCAGTGATTGGAACAGGACTGGATGTGTTTTATCCTAAAGCCAATAAACGCTTGCAAGACTACATCGGCAATGA
CCATCTGGTTTTAAGTGAATATGGACCTGGCGAACAACCTCTGAAATTTCATTTTCCTGCCCGTAATCGCATCATTGCTG
GACTTTGTCGTGGTGTGATTGTAGCAGAGGCTAAGATGCGTTCAGGTAGTCTCATTACGTGTGAGCGAGCAATGGAAGAA
GGACGCGATGTCTTTGCTATTCCTGCTAGCATTTTAGATGGACTATCAGACGGTTGCCATCATTTGATTCAAGAAGGAGC
AAAATTGGTCACCAGTGGGCAAGATGTTCTTGCGGAATTTGAATTTTAA

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (75-271)

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (3-64)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	99.645	100	0.996
dprA/cilB/dalA	Streptococcus pneumoniae D39	99.645	100	0.996
dprA/cilB/dalA	Streptococcus pneumoniae R6	99.645	100	0.996
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	99.645	100	0.996
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	98.227	100	0.982
dprA/cilB/dalA	Streptococcus mitis SK321	97.518	100	0.975
dprA	Streptococcus mutans UA159	62.857	99.291	0.624
dprA	Lactococcus lactis subsp. cremoris KW2	55.357	99.291	0.55
dprA	Staphylococcus aureus N315	37.456	100	0.376