Detailed information NTG0047172

Bioinformatically predicted

Overview

• Name: codY
• Type: Regulator
• Locus tag: SAI2T2_RS05985
• Genome accession: NC_020564
• Coordinates: 1222621..1223394 (+)
• Length: 257 a.a.
• NCBI ID: WP_000055337.1
• Uniprot ID: P63843
• Organism: Staphylococcus aureus subsp. aureus ST228
• Function: repression of comK (predicted from homology) Competence regulation

Genomic Context

Location: 1217621..1228394

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SAI2T2_RS05965 (SAI2T2_1008960)	trmFO	1217964..1219271 (+)	1308	WP_000195254.1	methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO	-
SAI2T2_RS05970 (SAI2T2_1008970)	xerC	1219689..1220585 (+)	897	WP_001015601.1	tyrosine recombinase XerC	-
SAI2T2_RS05975 (SAI2T2_1008980)	hslV	1220582..1221127 (+)	546	WP_000072681.1	ATP-dependent protease subunit HslV	-
SAI2T2_RS05980 (SAI2T2_1008990)	hslU	1221193..1222596 (+)	1404	WP_000379054.1	ATP-dependent protease ATPase subunit HslU	-
SAI2T2_RS05985 (SAI2T2_1009000)	codY	1222621..1223394 (+)	774	WP_000055337.1	GTP-sensing pleiotropic transcriptional regulator CodY	Regulator
SAI2T2_RS14500	-	1223468..1223542 (+)	75	WP_031761472.1	hypothetical protein	-
SAI2T2_RS05995 (SAI2T2_1009010)	rpsB	1223741..1224508 (+)	768	WP_000268484.1	30S ribosomal protein S2	-
SAI2T2_RS14505	-	1224542..1224655 (+)	114	WP_001789890.1	hypothetical protein	-
SAI2T2_RS06005 (SAI2T2_1009020)	tsf	1224690..1225571 (+)	882	WP_000201392.1	translation elongation factor Ts	-
SAI2T2_RS06010 (SAI2T2_1009030)	pyrH	1225708..1226430 (+)	723	WP_000057330.1	UMP kinase	-
SAI2T2_RS06015 (SAI2T2_1009040)	frr	1226449..1227003 (+)	555	WP_001280006.1	ribosome recycling factor	-
SAI2T2_RS06020 (SAI2T2_1009050)	-	1227376..1228146 (+)	771	WP_000473699.1	isoprenyl transferase	-

Sequence

Protein

• Length: 257 a.a.
• Molecular weight: 28755.13 Da
• Isoelectric Point: 6.0680

>NTDB_id=47172 SAI2T2_RS05985 WP_000055337.1 1222621..1223394(+) (codY) [Staphylococcus aureus subsp. aureus ST228]
MSLLSKTRELNTLLQKHKGIAVDFKDVAQTISSVTVTNVFIVSRRGKILGSSLNELLKSQRIIQMLEERHIPSEYTERLM
EVKQTESNIDIDNVLTVFPPENRELFIDSRTTIFPILGGGERLGTLVLGRVHDDFNENDLVLGEYAATVIGMEILREKHS
EVEKEARDKAAITMAINSLSYSEKEAIEHIFEELGGTEGLLIASKVADRVGITRSVIVNALRKLESAGVIESRSLGMKGT
FIKVKKEKFLDELEKSK

Nucleotide

• Length: 774 bp

>NTDB_id=47172 SAI2T2_RS05985 WP_000055337.1 1222621..1223394(+) (codY) [Staphylococcus aureus subsp. aureus ST228]
ATGAGCTTATTATCTAAAACGAGAGAGTTAAACACGTTACTTCAAAAACACAAAGGTATTGCGGTTGATTTTAAAGATGT
AGCACAAACGATTAGTAGCGTAACTGTAACAAATGTATTTATTGTATCGCGTCGAGGTAAAATTTTAGGGTCGAGTCTAA
ATGAATTATTAAAAAGTCAAAGAATTATTCAAATGTTGGAAGAAAGACATATTCCAAGTGAATATACAGAACGATTAATG
GAAGTTAAACAAACAGAATCAAATATTGATATCGACAATGTATTAACAGTATTCCCACCTGAAAACAGAGAATTATTCAT
AGATAGTCGTACAACTATCTTCCCAATTTTAGGTGGAGGAGAAAGATTAGGTACATTAGTACTTGGTCGAGTACATGATG
ATTTTAATGAAAATGATTTGGTACTAGGTGAATATGCTGCTACAGTTATTGGTATGGAAATCTTACGTGAGAAGCATAGT
GAAGTAGAAAAAGAAGCGCGCGATAAAGCTGCTATTACAATGGCAATTAATTCATTATCTTATTCTGAAAAAGAAGCGAT
TGAACATATCTTTGAAGAACTTGGCGGTACGGAAGGCCTATTAATCGCATCAAAAGTTGCAGATAGAGTTGGTATTACTA
GATCTGTAATTGTAAATGCACTACGTAAATTAGAAAGTGCTGGTGTAATTGAATCACGTTCTTTAGGAATGAAAGGTACT
TTCATTAAAGTTAAAAAAGAAAAATTCTTAGATGAATTAGAAAAAAGTAAATAA

Domains

Predicted by InterProScan.

• CodY GAF-like domain (CodY) (2-178)

• CodY helix-turn-helix domain (HTH_CodY) (198-255)

3D structure

• AlphaFold DB: P63843

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
codY	Bacillus subtilis subsp. subtilis str. 168	64.202	100	0.642
codY	Lactococcus lactis subsp. lactis strain DGCC12653	42.802	100	0.428