Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB2   Type   Machinery gene
Locus tag   HPCU_RS00085 Genome accession   NC_017358
Coordinates   11533..11814 (+) Length   93 a.a.
NCBI ID   WP_001272686.1    Uniprot ID   G2MDJ3
Organism   Helicobacter pylori Cuz20     
Function   transformation-associated type IV transport system (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 6533..16814
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HPCU_RS00065 (HPCU_00045) groES 7107..7463 (-) 357 WP_000671956.1 co-chaperone GroES -
  HPCU_RS00070 (HPCU_00050) dnaG 7738..9417 (+) 1680 WP_000601631.1 DNA primase -
  HPCU_RS00075 (HPCU_00055) - 9414..10466 (+) 1053 WP_000802571.1 MnmA/TRMU family protein -
  HPCU_RS00080 (HPCU_00060) - 10558..11385 (+) 828 WP_001154896.1 DUF5718 family protein -
  HPCU_RS00085 (HPCU_00065) comB2 11533..11814 (+) 282 WP_001272686.1 TrbC/VirB2 family protein Machinery gene
  HPCU_RS00090 (HPCU_00070) comB3 11814..12077 (+) 264 WP_000584940.1 hypothetical protein Machinery gene
  HPCU_RS00095 (HPCU_00075) comB4 12079..14442 (+) 2364 WP_000890505.1 VirB4 family type IV secretion/conjugal transfer ATPase Machinery gene
  HPCU_RS00100 (HPCU_00080) - 14763..16103 (+) 1341 WP_014534166.1 COG3014 family protein -

Sequence

Protein


Download         Length: 93 a.a.        Molecular weight: 10539.81 Da        Isoelectric Point: 9.1450

>NTDB_id=46741 HPCU_RS00085 WP_001272686.1 11533..11814(+) (comB2) [Helicobacter pylori Cuz20]
MSAHFLKIIFLVGMCVSSLFAEGLEGFFNALEAQLKSPIAKGILMVIFIGIAIYVWRNLDRWKEILFTILGVVFGIFLFF
KAPSLANWFMGIF

Nucleotide


Download         Length: 282 bp        

>NTDB_id=46741 HPCU_RS00085 WP_001272686.1 11533..11814(+) (comB2) [Helicobacter pylori Cuz20]
ATGTCCGCTCATTTTTTAAAAATCATTTTTTTAGTAGGCATGTGCGTTTCAAGTTTGTTCGCTGAAGGTTTAGAGGGGTT
TTTTAACGCCCTAGAAGCCCAGCTCAAAAGCCCCATCGCTAAGGGGATTTTAATGGTGATTTTCATAGGGATCGCTATTT
ATGTGTGGAGGAATTTGGACCGGTGGAAAGAGATTTTATTCACGATCCTTGGCGTGGTGTTTGGGATTTTTTTATTCTTT
AAAGCCCCGAGTTTAGCGAATTGGTTCATGGGAATTTTTTAA

Domains

Predicted by InterproScan.

TrbC/VIRB2 pilin (TrbC)

(6-89)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB G2MDJ3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB2 Helicobacter pylori 26695

98.925

100

0.989

Multiple sequence alignment