Detailed information NTG0464682

Bioinformatically predicted

Overview

• Name: codY
• Type: Regulator
• Locus tag: JQR77_RS07675
• Genome accession: NZ_CP069275
• Coordinates: 1497250..1498035 (-)
• Length: 261 a.a.
• NCBI ID: WP_002951720.1
• Uniprot ID: Q5M305
• Organism: Streptococcus thermophilus strain EG007
• Function: repress the expression of comX (predicted from homology) Competence regulation

Genomic Context

Location: 1492250..1503035

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
JQR77_RS07640 (JQR77_07650)	gatC	1492314..1492616 (-)	303	WP_002884769.1	Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC	-
JQR77_RS07645 (JQR77_07655)	-	1492791..1493009 (-)	219	WP_014621899.1	glycosyl transferase	-
JQR77_RS07650	-	1492948..1493112 (-)	165	WP_231838381.1	glycosyltransferase	-
JQR77_RS07655 (JQR77_07665)	-	1493549..1494990 (-)	1442	Protein_1462	6-phospho-beta-glucosidase	-
JQR77_RS07660 (JQR77_07670)	msrA	1495143..1495652 (-)	510	WP_024703984.1	peptide-methionine (S)-S-oxide reductase MsrA	-
JQR77_RS07665 (JQR77_07675)	-	1495664..1496512 (-)	849	WP_024703985.1	MetQ/NlpA family ABC transporter substrate-binding protein	-
JQR77_RS07670 (JQR77_07680)	-	1496636..1497187 (-)	552	WP_002946999.1	cysteine hydrolase family protein	-
JQR77_RS07675 (JQR77_07685)	codY	1497250..1498035 (-)	786	WP_002951720.1	GTP-sensing pleiotropic transcriptional regulator CodY	Regulator
JQR77_RS07680 (JQR77_07690)	-	1498295..1499509 (-)	1215	WP_002951721.1	pyridoxal phosphate-dependent aminotransferase	-
JQR77_RS07685 (JQR77_07695)	-	1499864..1500316 (+)	453	WP_002946987.1	universal stress protein	-
JQR77_RS07690	-	1500496..1501067 (+)	572	Protein_1469	IS30 family transposase	-
JQR77_RS07695 (JQR77_07700)	-	1501139..1501312 (-)	174	WP_011681546.1	hypothetical protein	-
JQR77_RS07700 (JQR77_07705)	-	1501373..1501747 (-)	375	WP_084825650.1	hypothetical protein	-
JQR77_RS07705 (JQR77_07710)	pflA	1501959..1502759 (-)	801	WP_002946980.1	pyruvate formate-lyase-activating protein	-

Sequence

Protein

• Length: 261 a.a.
• Molecular weight: 28919.13 Da
• Isoelectric Point: 4.5802

>NTDB_id=464682 JQR77_RS07675 WP_002951720.1 1497250..1498035(-) (codY) [Streptococcus thermophilus strain EG007]
MANLLDKTRKITSILQRSVDSLEGDLPYNNMAAQLADIIDCNAAIVNGGGALLGFAMKYKTNNDRVEKFFKAKQLPEEYI
RGISRVYDTQENIGIDSDLTIFPVELKDDFPDGLTTIAPIYGGGMRLGSFIIWRNDHDFVDDDLILVEIASTVVGLQLLH
LQTENLEETIRKQTAINMAINTLSYSEIKAVSAILNELDGLEGRLTASVIADRIGITRSVIVNALRKLESAGIIESRSLG
MKGTYLKVLNEGIYDKLKEYE

Nucleotide

• Length: 786 bp

>NTDB_id=464682 JQR77_RS07675 WP_002951720.1 1497250..1498035(-) (codY) [Streptococcus thermophilus strain EG007]
ATGGCAAATTTGCTTGATAAAACACGTAAAATTACTTCTATCTTGCAACGCTCAGTAGATAGTTTGGAAGGAGATCTTCC
ATACAACAACATGGCTGCTCAGTTGGCAGATATTATTGATTGTAATGCTGCTATTGTAAATGGTGGAGGTGCTCTCCTTG
GTTTTGCTATGAAATACAAAACCAACAATGACCGTGTGGAAAAGTTTTTTAAAGCTAAACAACTTCCAGAGGAATACATA
CGTGGTATCAGCCGTGTTTATGATACTCAAGAAAATATCGGTATTGACAGTGACTTGACCATCTTCCCAGTGGAATTAAA
AGATGATTTCCCTGACGGTTTGACTACAATTGCACCAATCTATGGTGGTGGTATGCGTCTTGGTTCTTTCATTATTTGGC
GTAACGACCATGATTTTGTGGACGACGACCTTATCTTGGTTGAGATTGCATCTACAGTAGTTGGTTTGCAATTGTTGCAT
CTTCAAACAGAAAACTTGGAAGAAACGATTCGTAAACAAACAGCTATTAATATGGCTATTAATACCTTGTCTTACTCAGA
AATCAAGGCAGTTTCAGCTATCTTGAATGAGTTGGACGGTTTAGAAGGTCGTTTGACAGCCTCTGTTATCGCGGACCGTA
TCGGAATTACTCGTTCTGTTATTGTTAATGCTCTTCGTAAATTAGAATCAGCTGGTATTATTGAAAGTCGTTCGCTTGGT
ATGAAAGGCACTTACCTTAAAGTCCTTAACGAAGGTATCTACGACAAATTGAAAGAATACGAATAA

Domains

Predicted by InterProScan.

• CodY GAF-like domain (CodY) (3-182)

• CodY helix-turn-helix domain (HTH_CodY) (201-261)

3D structure

• AlphaFold DB: Q5M305

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
codY	Lactococcus lactis subsp. lactis strain DGCC12653	64.591	98.467	0.636
codY	Bacillus subtilis subsp. subtilis str. 168	53.036	94.636	0.502