Detailed information
Bioinformatically predicted
Overview
| Name | comB3 | Type | Machinery gene |
| Locus tag | HWU11_RS06740 | Genome accession | NZ_CP058285 |
| Coordinates | 1399045..1399308 (+) | Length | 87 a.a. |
| NCBI ID | WP_001177716.1 | Uniprot ID | T0EUE0 |
| Organism | Helicobacter pylori strain BT302 | ||
| Function | transformation-associated type IV transport system (predicted from homology) DNA binding and uptake |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| ICE | 1381528..1408739 | 1399045..1399308 | within | 0 |
| IScluster/Tn | 1400243..1402148 | 1399045..1399308 | flank | 935 |
Gene organization within MGE regions
Location: 1381528..1408739
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| HWU11_RS06655 | clpX | 1381528..1382874 (-) | 1347 | WP_001006324.1 | ATP-dependent protease ATP-binding subunit ClpX | - |
| HWU11_RS06660 | lpxA | 1382876..1383688 (-) | 813 | WP_140522782.1 | acyl-ACP--UDP-N-acetylglucosamine O-acyltransferase | - |
| HWU11_RS06665 | fabZ | 1383692..1384171 (-) | 480 | WP_020982532.1 | 3-hydroxyacyl-ACP dehydratase FabZ | - |
| HWU11_RS07900 | - | 1384219..1384395 (+) | 177 | WP_419772972.1 | flavoprotein oxidoreductase | - |
| HWU11_RS06670 | fliW | 1384353..1384742 (-) | 390 | WP_033617084.1 | flagellar assembly protein FliW | - |
| HWU11_RS06675 | - | 1384959..1385105 (+) | 147 | WP_237008327.1 | hypothetical protein | - |
| HWU11_RS06680 | - | 1385146..1385808 (+) | 663 | WP_017284240.1 | outer membrane protein assembly factor BamD | - |
| HWU11_RS06685 | lon | 1385851..1388319 (+) | 2469 | WP_237008328.1 | endopeptidase La | - |
| HWU11_RS06690 | - | 1388328..1389155 (+) | 828 | WP_120917289.1 | prephenate dehydrogenase | - |
| HWU11_RS06695 | - | 1389481..1390344 (-) | 864 | WP_237008329.1 | DNA/RNA non-specific endonuclease | - |
| HWU11_RS06700 | - | 1390465..1392397 (-) | 1933 | Protein_1311 | DNA methyltransferase | - |
| HWU11_RS06705 | - | 1392391..1394934 (-) | 2544 | WP_237008955.1 | DEAD/DEAH box helicase family protein | - |
| HWU11_RS06710 | - | 1395140..1395988 (+) | 849 | WP_237008331.1 | biotin synthase | - |
| HWU11_RS06715 | - | 1395988..1396866 (+) | 879 | WP_100981985.1 | YihY family inner membrane protein | - |
| HWU11_RS06720 | - | 1397259..1398047 (+) | 789 | WP_237008956.1 | integrase | - |
| HWU11_RS06725 | - | 1398050..1398280 (+) | 231 | WP_237008332.1 | hypothetical protein | - |
| HWU11_RS06730 | - | 1398273..1398752 (+) | 480 | WP_237008333.1 | hypothetical protein | - |
| HWU11_RS06735 | comB2 | 1398749..1399033 (+) | 285 | WP_000736106.1 | TrbC/VirB2 family protein | Machinery gene |
| HWU11_RS06740 | comB3 | 1399045..1399308 (+) | 264 | WP_001177716.1 | hypothetical protein | Machinery gene |
| HWU11_RS06745 | - | 1399320..1399553 (+) | 234 | WP_237008334.1 | hypothetical protein | - |
| HWU11_RS06750 | - | 1399553..1400206 (+) | 654 | Protein_1321 | transporter | - |
| HWU11_RS06755 | - | 1400243..1401520 (-) | 1278 | WP_237008113.1 | RNA-guided endonuclease InsQ/TnpB family protein | - |
| HWU11_RS06760 | - | 1401495..1402148 (-) | 654 | WP_033617249.1 | IS607-like element IS607 family transposase | - |
| HWU11_RS06765 | - | 1402201..1403667 (+) | 1467 | WP_237008335.1 | hypothetical protein | - |
| HWU11_RS06770 | - | 1403664..1404926 (+) | 1263 | WP_237008336.1 | type IV secretion system protein | - |
| HWU11_RS06775 | - | 1404923..1406200 (+) | 1278 | WP_237008337.1 | hypothetical protein | - |
| HWU11_RS06780 | - | 1406333..1406584 (+) | 252 | WP_000006537.1 | hypothetical protein | - |
| HWU11_RS06785 | - | 1406556..1407359 (+) | 804 | WP_000009099.1 | nucleotidyl transferase AbiEii/AbiGii toxin family protein | - |
| HWU11_RS06790 | - | 1407672..1408739 (-) | 1068 | WP_237008338.1 | tyrosine-type recombinase/integrase | - |
Sequence
Protein
Download Length: 87 a.a. Molecular weight: 9970.83 Da Isoelectric Point: 5.7206
>NTDB_id=463460 HWU11_RS06740 WP_001177716.1 1399045..1399308(+) (comB3) [Helicobacter pylori strain BT302]
MQLVGISVSNLKEISSKEKFLWLNAKSFLLSGFVPFIMIPWLDILNSFVLYVCFLLIFSIAEFFDEDISDILIAHSKIKT
KANSFYA
MQLVGISVSNLKEISSKEKFLWLNAKSFLLSGFVPFIMIPWLDILNSFVLYVCFLLIFSIAEFFDEDISDILIAHSKIKT
KANSFYA
Nucleotide
Download Length: 264 bp
>NTDB_id=463460 HWU11_RS06740 WP_001177716.1 1399045..1399308(+) (comB3) [Helicobacter pylori strain BT302]
ATGCAATTAGTTGGTATTTCAGTTTCTAATCTCAAAGAAATCAGCTCCAAAGAAAAATTTCTTTGGCTCAATGCTAAGAG
TTTTTTACTCTCAGGATTTGTGCCTTTTATTATGATACCTTGGCTAGATATATTGAACTCTTTTGTGCTTTATGTGTGCT
TTCTCTTAATTTTTAGCATAGCGGAGTTCTTTGATGAAGATATAAGTGACATTTTAATCGCTCATTCCAAAATTAAAACC
AAAGCTAATTCATTTTACGCTTAA
ATGCAATTAGTTGGTATTTCAGTTTCTAATCTCAAAGAAATCAGCTCCAAAGAAAAATTTCTTTGGCTCAATGCTAAGAG
TTTTTTACTCTCAGGATTTGTGCCTTTTATTATGATACCTTGGCTAGATATATTGAACTCTTTTGTGCTTTATGTGTGCT
TTCTCTTAATTTTTAGCATAGCGGAGTTCTTTGATGAAGATATAAGTGACATTTTAATCGCTCATTCCAAAATTAAAACC
AAAGCTAATTCATTTTACGCTTAA
Domains
No domain identified.
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| comB3 | Helicobacter pylori 26695 |
60.92 |
100 |
0.609 |