Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYH   Type   Machinery gene
Locus tag   HW271_RS06485 Genome accession   NZ_CP058258
Coordinates   1327861..1328814 (-) Length   317 a.a.
NCBI ID   WP_178895342.1    Uniprot ID   A0A7H8ZB22
Organism   Streptococcus sp. oral taxon 061 strain F0704     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1322861..1333814
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HW271_RS06460 (HW271_06460) - 1322883..1323371 (-) 489 WP_178895337.1 DUF5590 domain-containing protein -
  HW271_RS06465 (HW271_06465) - 1323633..1324181 (+) 549 WP_178895338.1 NADPH-dependent FMN reductase -
  HW271_RS06470 (HW271_06470) - 1324224..1325414 (-) 1191 WP_178895339.1 O-antigen ligase -
  HW271_RS06475 (HW271_06475) birA 1325626..1326561 (+) 936 WP_178895340.1 bifunctional biotin--[acetyl-CoA-carboxylase] ligase/biotin operon repressor BirA -
  HW271_RS06480 (HW271_06480) - 1326621..1327811 (-) 1191 WP_178895341.1 acetate kinase -
  HW271_RS06485 (HW271_06485) comYH 1327861..1328814 (-) 954 WP_178895342.1 class I SAM-dependent methyltransferase Machinery gene
  HW271_RS06490 (HW271_06490) - 1328911..1330518 (-) 1608 WP_178895343.1 CTP synthase -
  HW271_RS06495 (HW271_06495) rpoE 1330798..1331373 (-) 576 WP_006150244.1 DNA-directed RNA polymerase subunit delta -
  HW271_RS06500 (HW271_06500) - 1331551..1332750 (-) 1200 WP_178895344.1 ABC transporter permease -
  HW271_RS06505 (HW271_06505) - 1332747..1333640 (-) 894 WP_178895345.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 317 a.a.        Molecular weight: 35914.19 Da        Isoelectric Point: 4.4040

>NTDB_id=463232 HW271_RS06485 WP_178895342.1 1327861..1328814(-) (comYH) [Streptococcus sp. oral taxon 061 strain F0704]
MDFEKIEQAYTYLLENVQIIQNDLATSFYDALIEQNGIYLDGQTALEQVKKNNQALKRLALRKEEWLRTYQFLLMKAAQT
EPLQANHQFTPDAVGHLMIFIIEQLFPAENVSLLELGSGMGILGASFLTSMNKKIDYLGIELDDLLIDLAASMAEVMDLQ
MGFVQGDAVRPQVLKESDIIVSDLPVGYYPDDQTASRYQVAAKNEHTYAHHLLMEQSLKYLKTGGYAIFLAPTDLLTSPQ
SELLKSWLTEKAQLVAIIALPEDLFAHGAQSKTIFVLQKKTGEGIEPFVYPLTSLRDPEILMEFKENFQNWCQEHEI

Nucleotide


Download         Length: 954 bp        

>NTDB_id=463232 HW271_RS06485 WP_178895342.1 1327861..1328814(-) (comYH) [Streptococcus sp. oral taxon 061 strain F0704]
ATGGATTTTGAAAAAATTGAACAAGCATATACCTATTTACTAGAAAATGTCCAAATCATTCAAAACGATTTGGCGACAAG
CTTTTATGATGCCTTGATTGAACAAAATGGGATCTATCTCGATGGTCAAACCGCTCTGGAGCAAGTCAAAAAAAATAACC
AGGCCTTAAAACGTTTGGCACTTCGAAAAGAGGAGTGGTTACGGACCTATCAATTTTTGTTAATGAAGGCAGCGCAAACA
GAACCTCTTCAAGCAAATCACCAGTTCACACCGGATGCGGTTGGTCACTTGATGATTTTTATCATTGAACAACTTTTCCC
TGCTGAAAATGTGAGCTTATTGGAATTGGGATCTGGGATGGGAATTCTTGGAGCTAGTTTCTTAACGTCTATGAACAAAA
AGATAGATTACCTGGGAATAGAACTTGATGACCTCTTGATTGACTTGGCGGCAAGCATGGCAGAAGTAATGGATCTTCAA
ATGGGCTTTGTCCAAGGAGACGCAGTGCGTCCACAAGTATTAAAAGAAAGTGACATCATTGTGAGCGACCTGCCTGTCGG
TTACTATCCAGATGATCAGACAGCCTCACGTTATCAAGTAGCGGCTAAGAATGAACATACTTATGCTCATCATTTGTTAA
TGGAACAATCACTCAAGTATCTTAAAACAGGTGGTTATGCGATTTTTCTAGCTCCAACGGACCTCTTGACGAGCCCTCAG
AGTGAACTTTTAAAATCATGGCTGACTGAAAAAGCCCAACTAGTAGCAATCATAGCTTTACCAGAGGATCTCTTTGCACA
CGGAGCTCAGTCTAAAACAATTTTTGTTCTACAGAAGAAGACGGGAGAAGGGATTGAACCATTTGTTTATCCACTTACGA
GTCTTCGTGACCCTGAAATTTTGATGGAATTTAAGGAAAATTTTCAAAATTGGTGTCAAGAACATGAAATCTAA

Domains

Predicted by InterproScan.

N-6 DNA Methylase (N6_Mtase)

(69-282)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7H8ZB22

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYH Streptococcus mutans UA159

55.873

99.369

0.555
  comYH Streptococcus mutans UA140

55.556

99.369

0.552