Detailed information    

experimental Experimentally validated

Overview

Name   oppA   Type   Regulator
Locus tag   GPW51_RS08685 Genome accession   NZ_LR738721
Coordinates   1712533..1714323 (-) Length   596 a.a.
NCBI ID   WP_012775331.1    Uniprot ID   A0A060IG42
Organism   Streptococcus suis isolate S10     
Function   internalize XIP   
Competence regulation

Function

S. suis mutants of oppA, the binding subunit of the general oligopeptide transporter were not transformable, suggesting that it is required for the import of XIP.


Genomic Context

Location: 1707533..1719323
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GPW51_RS08665 - 1708340..1709242 (-) 903 WP_002938141.1 ABC transporter permease -
  GPW51_RS08670 opp4B 1709256..1710212 (-) 957 WP_002938143.1 oligopeptide ABC transporter permease -
  GPW51_RS08675 - 1710214..1711155 (-) 942 WP_012027759.1 ATP-binding cassette domain-containing protein -
  GPW51_RS08680 - 1711158..1712156 (-) 999 WP_002942324.1 ABC transporter ATP-binding protein -
  GPW51_RS08685 oppA 1712533..1714323 (-) 1791 WP_012775331.1 oligopeptide ABC transporter substrate-binding protein Regulator
  GPW51_RS08690 pbp3 1714536..1715777 (+) 1242 WP_012775332.1 D-alanyl-D-alanine carboxypeptidase PBP3 -
  GPW51_RS08695 sufB 1716030..1717445 (-) 1416 WP_002938151.1 Fe-S cluster assembly protein SufB -
  GPW51_RS08700 sufU 1717795..1718235 (-) 441 WP_012027765.1 Fe-S cluster assembly sulfur transfer protein SufU -

Sequence

Protein


Download         Length: 596 a.a.        Molecular weight: 65671.66 Da        Isoelectric Point: 4.6364

>NTDB_id=463 GPW51_RS08685 WP_012775331.1 1712533..1714323(-) (oppA) [Streptococcus suis isolate S10]
MKKTTKLFALAGVTLLSASVLAACGSKQSGAAKQELSFPAEVKQDGTAVADAQLKYAWVSPTTSSGLLIDELTENTTDST
FGGMVDISMFGYDGERKLDDSGLAKAEFDVKGKKITVSLTGKDYKWSDGESFTINDYIFTIKSMASKDYTGIRFDDKFLN
IEGMQEFVDGKASDISGIKKVDDYTVELTVKEMSPSMMYAGGDVPAYIQPEHIYKDIPVADWEKSEYSRTAKLVGMGPWK
IKEIVNGESITYVPNEYFFKGTKPKTSSLKIDIVSPDTIVSEMKAGNYDIAEMPVDQLDSYKDASNLNIVGQLESSYEYI
SFNFGKYDEAAGKNVMDENAKMNDVKLRQAIAYAIDTKTAGKSLYNGLYHPAKSLIISFFGDIHDSELEGYSYNPEKAKK
LLDEAGYKDVDGDGIREGKDGKAFKITFAARKRTEANEALVQQYIAWWKEVGLNVELYTGRTVEGKSFYNSVQANDAAID
MYAGGWSTGYDPNPSGLWGPIAAFNMSRFVSDENTKLLEAISSAESFDDKKNVENYKAWQKYAHEQAFAIPTFESEKITA
VNKRVKSYDTKYGSASGTGLAYEGIELTADKGVVAE

Nucleotide


Download         Length: 1791 bp        

>NTDB_id=463 GPW51_RS08685 WP_012775331.1 1712533..1714323(-) (oppA) [Streptococcus suis isolate S10]
ATGAAAAAGACAACGAAACTTTTTGCACTTGCAGGTGTGACTCTCCTTTCAGCATCTGTTCTTGCAGCATGTGGTTCAAA
ACAATCAGGTGCAGCAAAACAGGAATTGTCATTCCCGGCTGAAGTAAAACAAGATGGAACAGCAGTCGCAGATGCTCAAT
TGAAATATGCTTGGGTATCTCCTACAACTTCATCAGGTCTTTTAATTGATGAGTTGACTGAGAATACTACTGATTCAACA
TTTGGTGGTATGGTTGATATTTCAATGTTCGGTTACGACGGAGAACGTAAGTTGGACGACTCAGGTCTTGCCAAGGCTGA
ATTTGATGTAAAAGGCAAGAAAATCACAGTCAGCTTGACTGGTAAGGATTACAAGTGGTCAGATGGTGAGTCATTCACAA
TCAACGACTACATCTTTACAATTAAGTCGATGGCAAGCAAAGACTATACAGGTATTCGTTTTGATGATAAATTCTTGAAT
ATTGAAGGTATGCAAGAATTTGTTGATGGAAAAGCATCAGACATCTCTGGTATTAAGAAAGTTGATGACTATACAGTAGA
ATTAACTGTAAAAGAAATGTCACCTTCAATGATGTATGCAGGTGGTGATGTCCCAGCCTATATCCAACCAGAACACATCT
ATAAAGACATCCCTGTTGCAGACTGGGAAAAGAGCGAATACTCACGTACTGCGAAGCTTGTTGGTATGGGGCCGTGGAAG
ATTAAGGAAATCGTCAATGGTGAGTCTATCACTTACGTACCAAACGAATACTTCTTCAAGGGTACGAAACCAAAAACAAG
CTCATTGAAGATTGACATCGTATCTCCTGATACTATTGTTTCTGAAATGAAAGCGGGGAATTATGATATCGCAGAAATGC
CGGTTGATCAGTTAGATTCATATAAGGATGCTTCTAACTTGAATATCGTTGGTCAGTTAGAGTCGTCTTATGAGTATATC
TCGTTTAATTTTGGTAAATATGACGAAGCAGCTGGTAAGAACGTTATGGATGAAAATGCCAAGATGAATGATGTGAAACT
TCGTCAAGCGATTGCCTATGCGATTGATACCAAGACAGCTGGTAAGTCATTATACAACGGTCTTTACCACCCTGCAAAAT
CATTGATTATCTCATTCTTCGGCGATATTCATGATTCAGAGTTGGAAGGCTATTCATACAATCCTGAAAAAGCGAAAAAG
CTTTTGGATGAAGCTGGCTACAAAGATGTAGATGGTGATGGTATCCGTGAAGGCAAAGATGGTAAGGCATTCAAGATTAC
CTTTGCGGCTCGTAAACGTACTGAAGCTAACGAAGCGCTTGTACAACAATACATTGCTTGGTGGAAAGAAGTTGGCTTGA
ATGTCGAACTTTACACAGGACGTACAGTTGAAGGTAAGTCGTTCTATAACTCAGTTCAGGCTAATGATGCTGCTATTGAT
ATGTATGCTGGTGGATGGTCAACAGGTTACGATCCAAACCCAAGTGGTCTATGGGGGCCTATCGCAGCCTTCAATATGTC
ACGTTTCGTGTCCGATGAAAACACCAAGTTATTGGAAGCTATCAGCTCAGCAGAGTCGTTTGATGATAAGAAAAACGTTG
AGAACTATAAGGCTTGGCAAAAATATGCTCACGAGCAAGCATTTGCTATTCCAACGTTTGAGTCAGAAAAAATTACTGCT
GTTAATAAACGTGTGAAAAGCTATGATACAAAATACGGCTCAGCTTCGGGTACAGGTCTTGCTTATGAGGGTATCGAATT
GACAGCTGATAAGGGTGTAGTGGCAGAATAA

Domains

Predicted by InterproScan.

Bacterial extracellular solute-binding proteins, family 5 Middle (SBP_bac_5)

(103-499)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A060IG42

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value

References

[1] Edoardo Zaccaria et al. (2014) Control of competence for DNA transformation in streptococcus suis by genetically transferable pherotypes. PloS One 9(6):e99394. [PMID: 24968201]