Detailed information    

insolico Bioinformatically predicted

Overview

Name   mutS/mutS2   Type   Machinery gene
Locus tag   I6J12_RS08455 Genome accession   NZ_CP068060
Coordinates   1794570..1796900 (-) Length   776 a.a.
NCBI ID   WP_003034042.1    Uniprot ID   I0SK17
Organism   Streptococcus anginosus strain FDAARGOS_1155     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1789570..1801900
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6J12_RS08425 (I6J12_08425) - 1789664..1790443 (-) 780 WP_003033989.1 replication initiator protein A -
  I6J12_RS08430 (I6J12_08430) - 1790552..1791031 (-) 480 WP_231847317.1 ClbS/DfsB family four-helix bundle protein -
  I6J12_RS08435 (I6J12_08435) - 1791107..1791388 (-) 282 WP_020999853.1 CD1845 family protein -
  I6J12_RS08440 (I6J12_08440) - 1791407..1791712 (-) 306 Protein_1684 23S rRNA methyltransferase -
  I6J12_RS08445 (I6J12_08445) trxA 1792549..1792863 (-) 315 WP_003032965.1 thioredoxin -
  I6J12_RS08450 (I6J12_08450) - 1793089..1794507 (-) 1419 WP_003034010.1 C69 family dipeptidase -
  I6J12_RS08455 (I6J12_08455) mutS/mutS2 1794570..1796900 (-) 2331 WP_003034042.1 endonuclease MutS2 Machinery gene
  I6J12_RS08460 (I6J12_08460) - 1796961..1797509 (-) 549 WP_003034014.1 CvpA family protein -
  I6J12_RS08465 (I6J12_08465) - 1797506..1797811 (-) 306 WP_003034036.1 hypothetical protein -
  I6J12_RS08470 (I6J12_08470) rnhC 1797897..1798787 (+) 891 WP_003034026.1 ribonuclease HIII -
  I6J12_RS08475 (I6J12_08475) lepB 1798791..1799405 (+) 615 WP_003034019.1 signal peptidase I -

Sequence

Protein


Download         Length: 776 a.a.        Molecular weight: 87524.92 Da        Isoelectric Point: 5.9810

>NTDB_id=458828 I6J12_RS08455 WP_003034042.1 1794570..1796900(-) (mutS/mutS2) [Streptococcus anginosus strain FDAARGOS_1155]
MNRKILETLEFGKIKALFEPYLLTEQGRLELQQLFPSNKQERLETAFLEMTDMQQIFVQRPHFSLAATQDITGLTKRLEL
EGDLNIEEFLALKRVLAVTQELTDFYEDLENVELQRLNRLFENLVSFPSLQGALQAINEGGFVESFASDNLARIRRKIQE
NEVQVRDILQDILKTKGDMLADQVVASRNGRNVLPVKNTFRHRISGVVHDISASGNTVYIEPRAVVNLNEEITNARADER
YEILRILQELSNRIRPHAAEIANNAWIIGHLDFVRAKVRFMQERGAVVPKLSDRQDIRLLHVAHPLIENAVANDLYFAAD
LTEIVITGPNTGGKTIMLKTLGLAQLMAQSGLPILADEGSQVGIFDQIFADIGDEQSIEQSLSTFSSHMTNIVSILEQAD
ENALVLLDELGAGTDPQEGAALAMAILEDLRLRQVKTMATTHYPELKAYGIETEGVQNASMEFDTDSLRPTYRFMQGVPG
RSNAFEIARRLGLSVRVVKDAQELTDTDSDVNRVIERLEEQTLESRKRLDNIREVEQENLKFNRALKKLYNEFNREKETE
LNKARLEAQEIIDVALTESDTILKNLHAKSSLKPHEIIEAKSQLKKLAPETVDLSQNKVLKQAKKARKPKVGDDILVISY
GHRGTLVNQLKDGRWEAQVGLIKMTLEEAEFNLLKAEKEQPKKKQVNVVKRTTTSGPRARLDLRGKRYEEAMQELDAFID
QALLNNMAQVDIIHGIGTGVIREGVTKYLRRNKHVKSFGYAPQNAGGSGATIVVFK

Nucleotide


Download         Length: 2331 bp        

>NTDB_id=458828 I6J12_RS08455 WP_003034042.1 1794570..1796900(-) (mutS/mutS2) [Streptococcus anginosus strain FDAARGOS_1155]
ATGAATAGAAAAATTTTAGAAACATTAGAATTTGGGAAAATCAAGGCGCTCTTTGAACCCTATCTTCTGACAGAACAAGG
GCGCTTGGAATTGCAGCAGCTATTTCCATCCAATAAACAAGAAAGGCTGGAGACAGCATTCTTAGAAATGACGGACATGC
AGCAGATTTTTGTACAGCGTCCTCACTTCAGTCTGGCTGCGACCCAAGACATTACGGGCTTGACCAAGCGCTTGGAGCTG
GAAGGCGACTTAAACATTGAAGAATTTCTCGCTCTGAAGCGGGTTTTGGCTGTCACGCAAGAATTGACTGATTTTTATGA
GGATTTGGAAAATGTTGAGTTGCAAAGATTGAATCGGCTTTTTGAAAATTTGGTTTCTTTTCCGAGCTTGCAAGGAGCGT
TGCAGGCTATCAATGAGGGCGGATTTGTTGAAAGTTTTGCGAGTGACAATTTAGCTCGCATTCGCCGGAAAATTCAAGAA
AATGAAGTTCAAGTGAGAGATATTTTGCAAGATATCCTCAAAACCAAGGGCGATATGCTAGCAGATCAAGTAGTAGCCAG
TCGAAACGGTCGCAATGTTTTGCCGGTCAAAAATACATTCCGCCATCGTATCTCAGGCGTGGTGCATGATATTTCTGCTA
GTGGAAACACGGTGTATATCGAGCCGCGGGCGGTGGTCAATCTCAATGAAGAAATCACCAATGCGCGGGCAGACGAGCGC
TATGAGATTTTGCGGATTTTACAAGAATTGTCTAACCGCATTCGTCCGCATGCTGCTGAAATTGCCAATAATGCTTGGAT
TATCGGACATTTGGACTTTGTTCGAGCTAAGGTGCGTTTTATGCAGGAGAGAGGAGCGGTAGTGCCCAAGCTGTCTGACC
GTCAGGATATTCGACTGCTCCATGTTGCTCATCCCCTGATAGAAAATGCAGTAGCCAATGACCTGTACTTTGCGGCGGAT
TTGACTGAGATTGTCATCACGGGACCCAATACAGGCGGAAAGACGATTATGCTCAAAACCCTAGGCTTGGCTCAGCTTAT
GGCGCAGTCCGGTCTGCCTATTTTGGCAGATGAAGGGAGTCAAGTGGGGATTTTTGACCAAATCTTTGCGGACATTGGAG
ATGAGCAGTCTATTGAGCAGAGTTTGTCGACCTTCTCCAGCCACATGACGAATATTGTCTCTATTTTAGAGCAGGCTGAT
GAGAATGCCTTGGTGCTTTTGGACGAGCTGGGAGCAGGAACTGACCCGCAGGAAGGAGCAGCACTTGCTATGGCAATTCT
TGAGGACTTGCGGCTACGACAGGTCAAGACAATGGCGACGACCCACTACCCAGAGCTCAAAGCCTATGGGATTGAGACTG
AGGGAGTGCAAAATGCTAGCATGGAGTTTGATACAGATAGCCTAAGACCGACTTATCGTTTTATGCAGGGAGTGCCGGGT
CGCTCCAATGCTTTTGAGATCGCAAGGCGTTTAGGCCTGTCTGTTAGAGTGGTCAAGGATGCTCAAGAATTGACCGATAC
GGACAGCGATGTTAATCGCGTTATTGAGCGCTTGGAAGAGCAGACCTTGGAAAGCCGCAAGCGGTTGGATAATATCCGAG
AGGTGGAGCAAGAAAATCTCAAATTTAACCGCGCTCTTAAAAAGCTCTACAACGAGTTCAATCGGGAAAAAGAAACTGAG
CTAAATAAGGCAAGGCTGGAAGCGCAGGAAATCATTGATGTGGCGCTGACCGAGAGTGATACGATTCTCAAAAATCTACA
TGCTAAGTCCAGTCTCAAACCGCACGAAATTATTGAAGCCAAAAGCCAGCTGAAAAAATTAGCTCCGGAAACGGTGGACT
TGTCACAGAATAAAGTGCTGAAACAAGCTAAAAAAGCACGGAAACCAAAGGTGGGAGACGATATTCTGGTGATTAGCTAC
GGTCATAGAGGCACGCTTGTCAATCAGCTCAAAGACGGTCGCTGGGAAGCACAGGTGGGACTCATCAAGATGACCTTGGA
GGAAGCAGAGTTTAACCTGCTCAAAGCTGAAAAAGAACAGCCTAAGAAAAAGCAGGTCAATGTGGTGAAACGGACGACAA
CAAGCGGACCAAGAGCCAGATTGGACTTGCGAGGCAAGCGCTACGAAGAAGCCATGCAAGAGCTGGATGCCTTTATTGAC
CAAGCCTTGCTCAACAATATGGCGCAGGTAGACATTATCCACGGGATCGGGACGGGCGTCATTCGCGAAGGCGTCACCAA
ATATCTCCGCCGCAATAAGCATGTCAAGAGTTTCGGCTATGCACCGCAAAATGCTGGGGGCAGCGGAGCAACTATTGTGG
TGTTTAAGTAA

Domains

Predicted by InterProScan.

Smr domain (Smr)

(701-776)

MutS domain V (MutS_V)

(324-505)

MutS2 and Smr-associated SH3 domain (MSSS)

(631-669)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB I0SK17

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mutS/mutS2 Bacillus subtilis subsp. subtilis str. 168

39.594

100

0.402