Detailed information NTG0045769

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: THTHE16_RS01380
• Genome accession: NC_017272
• Coordinates: 246290..247294 (-)
• Length: 334 a.a.
• NCBI ID: WP_014509829.1
• Uniprot ID: F6DD68
• Organism: Thermus thermophilus SG0.5JP17-16
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 241290..252294

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
THTHE16_RS01355 (Ththe16_0259)	hisG	242184..242804 (+)	621	WP_008630916.1	ATP phosphoribosyltransferase	-
THTHE16_RS01360 (Ththe16_0260)	trmH	242801..243385 (+)	585	WP_014509826.1	tRNA (guanosine(18)-2'-O)-methyltransferase TrmH	-
THTHE16_RS01365 (Ththe16_0261)	-	243375..244328 (-)	954	WP_014509827.1	branched-chain amino acid transaminase	-
THTHE16_RS01370 (Ththe16_0262)	-	244315..245268 (-)	954	WP_014509828.1	hydrogen peroxide-inducible genes activator	-
THTHE16_RS01375 (Ththe16_0263)	-	245378..246286 (+)	909	WP_008630926.1	manganese catalase family protein	-
THTHE16_RS01380 (Ththe16_0264)	dprA	246290..247294 (-)	1005	WP_014509829.1	DNA-processing protein DprA	Machinery gene
THTHE16_RS01385 (Ththe16_0265)	era	247378..248283 (+)	906	WP_008630929.1	GTPase Era	-
THTHE16_RS01390 (Ththe16_0266)	-	248328..249215 (+)	888	WP_011174227.1	acyltransferase	-
THTHE16_RS01400 (Ththe16_0267)	-	249411..250385 (+)	975	WP_014509830.1	DHH family phosphoesterase	-
THTHE16_RS01405 (Ththe16_0268)	-	250363..250911 (-)	549	WP_014509831.1	Uma2 family endonuclease	-
THTHE16_RS01410 (Ththe16_0269)	-	250921..252141 (-)	1221	WP_014509832.1	2,3-bisphosphoglycerate-independent phosphoglycerate mutase	-

Sequence

Protein

• Length: 334 a.a.
• Molecular weight: 35899.59 Da
• Isoelectric Point: 5.8378

>NTDB_id=45769 THTHE16_RS01380 WP_014509829.1 246290..247294(-) (dprA) [Thermus thermophilus SG0.5JP17-16]
MDPLALALLPGIGPKRLLEVLKAEDPLGFLRERFPEAWQHLPEAEAQAERERGRAEALGVRILGLWEEGFPEGLKALPQP
PTHLYLKGELPPEREAVALVGTRRASPWALAFARKLARELSEAGLWVVSGLARGIDREAHLGALEAGGRTLGVLGSALDR
VYPPENRPLAQRMDLLSEFPFGTGPKPEFFPRRNRLIAGLSRAVVVVEAPLDSGALITARHALELGKEVLAVPGRPTDEN
SKGANRLIQDGAYPVLSAEDVLAYLGVAARPKPLPGLSPEEEALYALLQEKGEALPEALAMALGIPPERVLSLLTLLELK
GLARALPGGRYGPG

Nucleotide

• Length: 1005 bp

>NTDB_id=45769 THTHE16_RS01380 WP_014509829.1 246290..247294(-) (dprA) [Thermus thermophilus SG0.5JP17-16]
GTGGACCCCTTGGCCCTCGCCCTCCTCCCGGGCATCGGCCCCAAGCGGCTTTTGGAGGTCCTAAAGGCGGAGGACCCTCT
GGGCTTCCTGCGGGAGCGCTTCCCCGAGGCCTGGCAGCACCTCCCCGAGGCCGAAGCCCAGGCGGAAAGGGAAAGGGGGC
GCGCCGAGGCCCTGGGGGTGCGCATCCTGGGCCTCTGGGAGGAGGGCTTCCCCGAGGGTCTGAAGGCGCTTCCCCAGCCG
CCCACCCACCTCTACCTGAAGGGGGAGCTTCCCCCGGAAAGGGAGGCGGTGGCCCTCGTGGGCACGCGCCGGGCCTCCCC
TTGGGCCTTGGCCTTTGCCCGGAAGCTCGCCCGGGAGCTTTCCGAGGCCGGGCTCTGGGTGGTCTCGGGCCTCGCCCGGG
GCATAGACCGGGAGGCCCACCTCGGGGCCCTCGAGGCCGGGGGGCGCACCCTGGGCGTCCTGGGAAGCGCCCTGGACCGG
GTCTACCCCCCGGAAAACCGCCCTTTGGCCCAACGGATGGACCTCCTCTCCGAGTTCCCCTTCGGGACGGGCCCCAAGCC
CGAGTTCTTTCCCCGGCGGAACCGCCTCATCGCCGGGCTCTCCCGGGCGGTGGTCGTGGTGGAGGCCCCCCTGGACTCCG
GGGCCCTCATCACCGCCCGCCACGCCTTGGAGCTCGGCAAGGAGGTGCTGGCCGTCCCCGGAAGGCCCACGGACGAGAAC
TCCAAGGGGGCCAACCGCCTCATCCAGGACGGGGCCTACCCGGTGCTCTCCGCCGAGGACGTCCTTGCCTACCTGGGGGT
GGCCGCAAGGCCCAAACCCCTCCCGGGCCTCTCCCCGGAGGAGGAGGCCCTTTACGCCCTCCTGCAGGAAAAGGGGGAGG
CGCTCCCCGAGGCCCTGGCCATGGCCCTGGGGATCCCCCCGGAGCGGGTGCTCTCCCTCCTCACCCTCTTGGAGCTAAAG
GGCCTGGCCCGGGCCCTCCCGGGAGGGCGCTACGGGCCAGGCTAA

Domains

Predicted by InterproScan.

• DprA winged helix domain (DprA_WH) (268-329)

• DNA recombination-mediator protein A (DNA_processg_A) (56-255)

3D structure

• AlphaFold DB: F6DD68

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Thermus thermophilus HB27	96.707	100	0.967
dprA	Deinococcus radiodurans R1 = ATCC 13939 = DSM 20539	39.889	100	0.431
dprA	Vibrio campbellii strain DS40M4	39.385	100	0.422
dprA	Vibrio cholerae strain A1552	37.569	100	0.407