Detailed information    

insolico Bioinformatically predicted

Overview

Name   mutS/mutS2   Type   Machinery gene
Locus tag   JHX98_RS08040 Genome accession   NZ_CP067010
Coordinates   1570338..1572677 (-) Length   779 a.a.
NCBI ID   WP_076640768.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain iGAS376     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1565338..1577677
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JHX98_RS08000 (JHX98_08000) rpsR 1565628..1565867 (-) 240 WP_002983142.1 30S ribosomal protein S18 -
  JHX98_RS08005 (JHX98_08005) ssbA 1566032..1566523 (-) 492 WP_002993238.1 single-stranded DNA-binding protein Machinery gene
  JHX98_RS08010 (JHX98_08010) rpsF 1566545..1566835 (-) 291 WP_002983117.1 30S ribosomal protein S6 -
  JHX98_RS08015 (JHX98_08015) - 1567008..1567301 (-) 294 WP_002983113.1 hypothetical protein -
  JHX98_RS08020 (JHX98_08020) mutY 1567469..1568623 (+) 1155 WP_023077315.1 A/G-specific adenine glycosylase -
  JHX98_RS08025 (JHX98_08025) - 1568800..1569387 (+) 588 WP_011018189.1 helix-turn-helix transcriptional regulator -
  JHX98_RS08030 (JHX98_08030) trxA 1569439..1569771 (-) 333 WP_256363924.1 thioredoxin -
  JHX98_RS08035 (JHX98_08035) - 1569834..1570334 (-) 501 WP_011018191.1 phosphatase PAP2 family protein -
  JHX98_RS08040 (JHX98_08040) mutS/mutS2 1570338..1572677 (-) 2340 WP_076640768.1 endonuclease MutS2 Machinery gene
  JHX98_RS08045 (JHX98_08045) - 1572826..1573371 (-) 546 WP_002983087.1 CvpA family protein -
  JHX98_RS08050 (JHX98_08050) - 1573374..1573682 (-) 309 WP_002993251.1 hypothetical protein -
  JHX98_RS08055 (JHX98_08055) rnhC 1573839..1574741 (+) 903 WP_011888614.1 ribonuclease HIII -
  JHX98_RS08060 (JHX98_08060) lepB 1574752..1575345 (+) 594 WP_002983074.1 signal peptidase I -

Sequence

Protein


Download         Length: 779 a.a.        Molecular weight: 87840.03 Da        Isoelectric Point: 6.5465

>NTDB_id=457006 JHX98_RS08040 WP_076640768.1 1570338..1572677(-) (mutS/mutS2) [Streptococcus pyogenes strain iGAS376]
MNNKILEQLEFNKVKELLLPYLKTEQSQEELLELEPMTEASKIEKSFNEISDMEQIFVEHHSFGIVSLSSISESLKRLEL
SADLNIQELLAIKKVLQSSSDMIHFYSDLDNVSFQSLDRLFENLEQFPNLQGSFQAINDGGFLEHFASPELERIRRQLTN
SERRVRQILQDMLKEKAELLSENLIASRSGRSVLPVKNTYRNRISGVVHDISSSGSTVYIEPRAVVTLNEELTQLRADER
HEEGRILHAFSDLLRPHVATIRNNAWILGHLDFVRAKYLFMSDNKATIPKISNDSTLALINVRHPLLSNPVANDLHFDHD
LTAIVITGPNTGGKTIMLKTLGLAQLMGQSGLPVLADKGSKIAVFNNIFADIGDEQSIEQSLSTFSSHMTHIVSILNEAD
HNSLVLFDELGAGTDPQEGASLAMAILEHLRLSHIKTMATTHYPELKAYGIETNFVENASMEFDAETLSPTYRFMQGVPG
RSNAFEIASRLGLAPFIVKQAKQMTDSDSDVNRIIEQLEAQTLETRRRLDHIKEVEQENLKFNRAVKKLYNEFSHERDKE
LEKIYQEAQEIVDMALNESDTILKKLNDKSQLKPHEIIDAKAQIKKLAPQVDLSKNKVLNKAKKIKAARAPRIGDDIIVT
SYGQRGTLTSQLKDGRWEAQVGIIKMTLTHDEFTLVRVQEEQKVKNKQINVVKKADSSGPRARLDLRGKRYEEAMQELDH
FIDQALLNNMGQVDIIHGIGTGVIREGVTKYLRRHKHVKHFAYAPQNAGGSGATIVTLG

Nucleotide


Download         Length: 2340 bp        

>NTDB_id=457006 JHX98_RS08040 WP_076640768.1 1570338..1572677(-) (mutS/mutS2) [Streptococcus pyogenes strain iGAS376]
ATGAATAACAAGATTTTAGAGCAGTTAGAATTTAACAAAGTTAAGGAATTGCTATTACCTTATCTCAAGACAGAACAATC
CCAAGAAGAATTATTAGAGCTGGAGCCGATGACGGAGGCTTCTAAAATAGAAAAAAGTTTTAATGAAATTTCTGACATGG
AACAGATTTTTGTTGAACATCACTCATTTGGCATAGTCAGCCTAAGTTCAATCTCTGAGAGTTTAAAACGTTTAGAACTT
TCAGCTGATCTTAATATTCAAGAACTTTTGGCTATCAAAAAAGTTTTACAGAGTTCTTCGGATATGATTCACTTTTATTC
TGATTTGGATAATGTTTCTTTCCAATCTTTGGATCGTTTGTTTGAAAATTTGGAACAATTCCCTAATCTGCAAGGGTCTT
TTCAAGCTATCAATGATGGTGGTTTTTTAGAACATTTTGCGAGTCCAGAATTAGAGCGTATCCGTCGTCAATTAACAAAT
AGTGAACGACGGGTTCGTCAGATTTTACAGGATATGCTTAAGGAAAAAGCAGAGCTTTTATCAGAAAATCTAATCGCTAG
TCGTAGTGGACGAAGTGTCCTACCAGTAAAAAATACTTATCGGAATCGTATTTCTGGTGTGGTTCATGACATCTCTTCTT
CAGGAAGTACTGTTTATATTGAGCCTCGTGCTGTAGTTACACTAAACGAAGAGCTAACGCAGCTTAGAGCTGACGAACGC
CACGAAGAAGGTCGTATTTTACACGCATTTTCAGACTTGTTAAGACCTCATGTCGCCACTATTAGAAATAATGCATGGAT
TCTTGGGCATCTTGATTTTGTAAGGGCTAAATATCTTTTTATGTCTGATAATAAGGCGACGATACCTAAGATTTCTAATG
ACAGCACGTTAGCATTAATCAATGTTCGTCATCCTCTTTTAAGTAATCCTGTGGCTAATGACTTACATTTTGATCACGAT
TTAACTGCAATTGTCATTACTGGTCCCAATACTGGTGGTAAGACGATTATGCTAAAAACACTCGGTTTAGCACAATTAAT
GGGACAGTCTGGTTTGCCAGTATTAGCGGATAAAGGTAGTAAAATTGCAGTATTTAACAATATCTTTGCAGATATTGGCG
ATGAGCAATCTATTGAACAAAGTCTATCAACTTTTTCTAGTCATATGACGCACATAGTCAGTATTTTAAACGAGGCTGAC
CACAATAGTTTAGTTCTCTTTGATGAACTAGGAGCAGGAACGGATCCTCAAGAAGGTGCTAGTTTGGCCATGGCTATTTT
AGAACACCTTAGGTTAAGTCATATCAAAACGATGGCGACCACGCACTATCCAGAATTAAAAGCTTATGGGATTGAGACAA
ATTTTGTAGAGAATGCGAGCATGGAATTTGATGCAGAAACGCTTAGCCCCACATATCGCTTTATGCAAGGAGTTCCTGGA
CGCTCAAATGCATTTGAAATTGCTTCTCGCCTTGGTTTAGCTCCATTTATTGTTAAACAAGCTAAGCAGATGACAGATTC
TGACTCAGATGTTAACCGTATTATTGAACAGTTAGAGGCACAGACACTTGAGACACGTAGAAGACTGGATCATATTAAAG
AAGTTGAACAAGAAAACCTCAAATTCAATCGTGCGGTTAAGAAACTCTATAATGAATTTTCACATGAACGCGATAAAGAG
TTAGAAAAAATCTATCAAGAAGCTCAAGAAATTGTAGATATGGCTTTGAATGAGAGTGATACTATCTTAAAAAAACTCAA
TGATAAGAGTCAATTAAAACCTCACGAAATTATAGATGCTAAGGCACAAATAAAAAAATTAGCGCCTCAAGTTGATTTAT
CAAAAAATAAAGTCTTAAATAAGGCTAAAAAAATCAAAGCAGCTCGTGCCCCTAGAATTGGTGATGATATTATAGTGACT
AGCTATGGACAGCGAGGTACCTTAACTAGTCAATTAAAAGATGGCCGTTGGGAAGCACAAGTGGGAATTATCAAAATGAC
ATTAACACATGATGAATTTACCCTCGTTAGAGTCCAAGAAGAACAAAAAGTCAAAAATAAACAGATTAATGTGGTTAAAA
AGGCTGATAGTTCTGGACCAAGAGCTCGACTTGATCTTAGAGGTAAAAGATACGAAGAAGCTATGCAAGAGTTAGATCAT
TTTATTGATCAAGCATTGCTTAACAATATGGGACAAGTTGATATCATTCATGGGATTGGTACAGGCGTTATCCGTGAGGG
AGTGACAAAATATCTTCGTCGTCATAAGCATGTTAAGCATTTTGCTTATGCCCCACAAAATGCAGGGGGATCTGGCGCCA
CAATTGTAACGTTAGGGTAA

Domains

Predicted by InterProScan.

Smr domain (Smr)

(704-778)

MutS2 and Smr-associated SH3 domain (MSSS)

(633-668)

MutS domain V (MutS_V)

(324-505)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mutS/mutS2 Bacillus subtilis subsp. subtilis str. 168

40.759

100

0.413