Detailed information    

insolico Bioinformatically predicted

Overview

Name   codY   Type   Regulator
Locus tag   JHX97_RS07820 Genome accession   NZ_CP067009
Coordinates   1517246..1518028 (-) Length   260 a.a.
NCBI ID   WP_002983278.1    Uniprot ID   A2RCV3
Organism   Streptococcus pyogenes strain iGAS391     
Function   repress the expression of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1512246..1523028
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JHX97_RS07795 (JHX97_07795) gatB 1512344..1513783 (-) 1440 WP_011888633.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatB -
  JHX97_RS07800 (JHX97_07800) gatA 1513783..1515249 (-) 1467 WP_011888632.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA -
  JHX97_RS07805 (JHX97_07805) gatC 1515249..1515551 (-) 303 WP_002988561.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC -
  JHX97_RS07810 (JHX97_07810) - 1515783..1516068 (-) 286 Protein_1496 putative PEP-binding protein -
  JHX97_RS07815 (JHX97_07815) - 1516545..1517099 (-) 555 WP_002988559.1 isochorismatase family cysteine hydrolase -
  JHX97_RS07820 (JHX97_07820) codY 1517246..1518028 (-) 783 WP_002983278.1 GTP-sensing pleiotropic transcriptional regulator CodY Regulator
  JHX97_RS07825 (JHX97_07825) - 1518246..1519460 (-) 1215 WP_200221135.1 pyridoxal phosphate-dependent aminotransferase -
  JHX97_RS07830 (JHX97_07830) - 1519691..1520143 (+) 453 WP_002992571.1 universal stress protein -
  JHX97_RS07835 (JHX97_07835) - 1520266..1521654 (-) 1389 WP_011888631.1 Cof-type HAD-IIB family hydrolase -
  JHX97_RS07840 (JHX97_07840) - 1521726..1522691 (+) 966 WP_002983258.1 asparaginase -

Sequence

Protein


Download         Length: 260 a.a.        Molecular weight: 28633.76 Da        Isoelectric Point: 4.5611

>NTDB_id=456906 JHX97_RS07820 WP_002983278.1 1517246..1518028(-) (codY) [Streptococcus pyogenes strain iGAS391]
MPNLLEKTRKITSILQRSVDSLETELPYNTMASRLADIIDCNACIINGGGTLLGYAMKYKTNTDRVEEFFEAKQFPDTYV
KAASRVYDTEANLSVENELTIFPVESKDTYPGGLTTIAPIYGGGMRLGSLIIWRNDNEFSDDDLILVEISSTVVGIQLLN
LQTENLEDTIRKQTAVNMAINTLSYSEMKAVAAILGELDGNEGRLTASVIADRIGITRSVIVNALRKLESAGIIESRSLG
MKGTYLKVINEGIFAKLKEF

Nucleotide


Download         Length: 783 bp        

>NTDB_id=456906 JHX97_RS07820 WP_002983278.1 1517246..1518028(-) (codY) [Streptococcus pyogenes strain iGAS391]
ATGCCTAACTTATTAGAAAAAACTCGTAAAATCACATCTATTTTGCAGCGTTCCGTAGATAGCCTAGAAACAGAATTACC
GTATAACACAATGGCATCTCGCCTAGCAGATATCATTGACTGCAATGCTTGTATTATCAATGGCGGCGGCACACTGCTTG
GTTATGCCATGAAATATAAAACTAACACTGATCGTGTTGAGGAATTTTTTGAAGCTAAACAATTTCCAGATACTTATGTA
AAGGCTGCTAGCCGAGTTTACGATACAGAAGCTAACCTTTCTGTCGAAAATGAATTGACTATATTCCCTGTTGAGTCTAA
AGACACTTATCCAGGAGGTCTAACGACTATTGCGCCGATTTATGGTGGAGGGATGCGCCTTGGATCACTCATTATCTGGC
GTAATGACAATGAATTTAGTGATGATGATTTGATCTTGGTTGAGATCTCAAGTACTGTTGTGGGGATTCAACTATTAAAT
CTTCAGACAGAAAACTTAGAAGACACCATCCGTAAACAAACAGCGGTCAACATGGCAATTAATACGCTTTCTTATTCAGA
AATGAAAGCTGTTGCAGCAATTCTTGGAGAGTTAGATGGTAATGAAGGACGATTGACAGCTTCTGTTATTGCTGATCGTA
TTGGTATTACCCGTTCTGTTATTGTCAATGCTCTGCGTAAACTAGAAAGTGCAGGGATTATTGAAAGTCGTTCTCTTGGT
ATGAAAGGGACATACCTCAAAGTTATCAACGAAGGTATTTTTGCTAAATTAAAAGAATTTTAA

Domains

Predicted by InterProScan.

CodY helix-turn-helix domain (HTH_CodY)

(202-260)

CodY GAF-like domain (CodY)

(3-182)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A2RCV3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  codY Lactococcus lactis subsp. lactis strain DGCC12653

66.148

98.846

0.654
  codY Bacillus subtilis subsp. subtilis str. 168

51.373

98.077

0.504