Detailed information NTG0045505

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: VPBB_RS02680
• Genome accession: NC_019955
• Coordinates: 574893..577466 (+)
• Length: 857 a.a.
• NCBI ID: WP_005460310.1
• Uniprot ID: Q87S63
• Organism: Vibrio parahaemolyticus BB22OP
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 569893..582466

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
VPBB_RS02655 (VPBB_0529)	raiA	569900..570226 (-)	327	WP_005468590.1	ribosome-associated translation inhibitor RaiA	-
VPBB_RS02660 (VPBB_0530)	-	570556..572037 (-)	1482	WP_015296270.1	lytic transglycosylase F	-
VPBB_RS02665 (VPBB_0531)	comL	572173..572901 (-)	729	WP_005460312.1	outer membrane protein assembly factor BamD	Machinery gene
VPBB_RS02670 (VPBB_0532)	rluD	573038..574015 (+)	978	WP_005460300.1	23S rRNA pseudouridine(1911/1915/1917) synthase RluD	-
VPBB_RS02675 (VPBB_0533)	pgeF	574017..574745 (+)	729	WP_015296271.1	peptidoglycan editing factor PgeF	-
VPBB_RS02680 (VPBB_0534)	clpC	574893..577466 (+)	2574	WP_005460310.1	ATP-dependent chaperone ClpB	Regulator

Sequence

Protein

• Length: 857 a.a.
• Molecular weight: 95872.46 Da
• Isoelectric Point: 5.1096

>NTDB_id=45505 VPBB_RS02680 WP_005460310.1 574893..577466(+) (clpC) [Vibrio parahaemolyticus BB22OP]
MRLDRFTSKFQIAISDAQSLALGRDHQYIEPVHLMVALLDQNGSPIRPLLTMLDVDVTHLRSKLGEMLDRLPKVSGIGGD
VQLSSSMGTLFNLCDKVAQKRQDSYISSEVFLLAALEDRGPLGQLLKEVGLTEQKVSQAIEKIRGGQKVNDPNAEELRQA
LEKFTIDLTERAEQGKLDPVIGRDDEIRRTIQVLQRRTKNNPVIIGEPGVGKTAIVEGLAQRIVNNEVPEGLRGRRVLSL
DMGALVAGAKYRGEFEERLKSVLNELAKEEGNVILFIDELHTMVGAGKGEGSMDAGNMLKPALARGELHCVGATTLDEYR
QYIEKDAALERRFQKVLVDEPTVEDTVAILRGLKERYELHHHVEITDPAIVAAASLSHRYISDRQLPDKAIDLIDEAASS
IRLQIDSKPESLDKLERKIIQLKIEQQALSNEHDEASEKRLQALNDELNEKEREYAELEEVWNTEKAALSGTQHIKSELE
QARMDMEFARRAGDLNRMSELQYGRIPELEKQLDLATQAEMQEMTLLRNKVTDNEIAEVLSKQTGIPVSKMLEAEKEKLL
RMEDVLHNRVVGQSEAVAVVSNAIRRSRAGLSDPNRPIGSFLFLGPTGVGKTELCKTLASFMFDSEDAMVRIDMSEFMEK
HSVARLVGAPPGYVGYEEGGYLTEAVRRKPYSVILLDEVEKAHPDVFNILLQVLDDGRLTDGQGRTVDFRNTVVIMTSNL
GSSRIQENFATLDYQGIKSEVMDVVSKHFRPEFLNRVDEIVVFHPLGQEHIKSIASIQLERLAKRLEEKGYQLEVSDKAL
DLIAQVGFDPVYGARPLKRAIQQNVENPLAKSILAGEIVPDKKVQLIVTNDQILAHQ

Nucleotide

• Length: 2574 bp

>NTDB_id=45505 VPBB_RS02680 WP_005460310.1 574893..577466(+) (clpC) [Vibrio parahaemolyticus BB22OP]
ATGCGTCTTGATAGATTTACCAGTAAGTTTCAAATCGCTATCTCTGATGCTCAATCACTAGCGTTAGGGCGCGATCATCA
GTACATCGAGCCAGTTCACTTAATGGTGGCTTTGCTTGATCAAAATGGCAGTCCAATTCGTCCATTGCTGACAATGCTGG
ACGTGGATGTAACTCATCTCCGCTCAAAGCTGGGCGAAATGCTTGATCGATTACCAAAGGTGAGTGGCATCGGTGGTGAT
GTGCAGCTTTCTAGCTCGATGGGGACTTTGTTCAATCTGTGTGACAAAGTGGCTCAAAAGCGTCAAGACTCCTACATCTC
GTCCGAAGTCTTCTTGCTTGCGGCATTAGAAGATCGTGGTCCTTTAGGGCAACTACTTAAAGAAGTTGGGCTGACCGAGC
AAAAAGTGAGTCAAGCGATTGAAAAGATCAGAGGTGGTCAAAAGGTCAATGATCCAAATGCTGAAGAGCTACGTCAGGCT
CTTGAAAAATTCACCATCGATTTAACTGAGCGAGCTGAGCAGGGCAAATTGGATCCTGTAATTGGTCGAGATGATGAAAT
TCGTCGCACGATTCAAGTATTGCAACGTCGCACCAAAAACAACCCAGTGATCATCGGTGAGCCTGGTGTGGGTAAAACCG
CAATTGTTGAAGGCTTGGCGCAGCGAATCGTTAATAACGAAGTGCCAGAAGGTCTACGCGGTCGCCGTGTTCTATCACTG
GATATGGGCGCACTTGTTGCTGGCGCGAAATACCGTGGTGAATTTGAAGAGCGTTTAAAATCAGTATTGAATGAACTTGC
TAAAGAAGAAGGCAACGTCATCCTCTTCATTGATGAACTACACACTATGGTCGGCGCTGGTAAAGGTGAAGGTTCAATGG
ATGCGGGCAACATGCTCAAACCAGCATTGGCTCGCGGCGAACTTCACTGTGTTGGTGCAACAACATTGGATGAGTACCGT
CAATACATCGAAAAGGATGCTGCATTAGAACGTCGTTTCCAAAAAGTGCTGGTGGATGAGCCGACAGTAGAAGATACGGT
AGCTATTCTTCGTGGTCTGAAAGAGCGTTATGAACTTCATCACCATGTAGAAATTACTGACCCAGCGATTGTTGCAGCGG
CAAGTTTGTCGCACCGTTATATTTCGGACCGTCAGTTGCCAGATAAAGCCATTGACTTGATCGATGAAGCGGCTTCAAGC
ATTCGTCTACAAATCGATTCAAAACCAGAATCATTGGATAAGCTTGAGCGTAAAATCATCCAACTAAAAATTGAGCAACA
AGCACTAAGTAACGAGCACGATGAAGCGAGTGAAAAGCGTCTGCAAGCATTGAATGATGAGTTGAATGAGAAAGAACGCG
AATACGCAGAGTTAGAAGAGGTTTGGAATACAGAAAAAGCCGCACTTTCTGGTACTCAGCATATTAAATCTGAACTAGAG
CAAGCTCGTATGGACATGGAGTTTGCGCGTCGTGCTGGCGATCTTAACCGAATGTCTGAGCTTCAATACGGTCGTATTCC
GGAATTAGAGAAGCAACTAGACTTGGCGACTCAGGCTGAAATGCAAGAAATGACGCTGCTTCGTAACAAAGTAACAGATA
ACGAAATCGCAGAAGTGCTTTCTAAACAAACCGGCATTCCAGTATCTAAGATGTTAGAAGCGGAGAAAGAGAAACTACTT
CGCATGGAAGATGTACTTCACAATCGTGTTGTAGGGCAAAGCGAAGCAGTTGCGGTGGTATCGAACGCGATTCGTCGTAG
CCGAGCTGGGCTTTCTGATCCAAACCGACCAATTGGTTCCTTCTTATTCTTAGGCCCAACTGGTGTCGGTAAAACGGAAT
TATGTAAGACACTTGCGAGCTTCATGTTCGACAGCGAAGATGCAATGGTACGTATCGACATGTCGGAGTTCATGGAGAAA
CACTCAGTGGCAAGATTAGTGGGTGCGCCTCCAGGTTACGTTGGTTACGAAGAGGGTGGTTATCTAACTGAAGCGGTTCG
TCGTAAACCATACTCAGTGATCTTGTTGGATGAAGTAGAAAAAGCACATCCAGATGTGTTCAATATTCTTCTGCAGGTGC
TTGATGATGGCCGACTCACAGATGGACAAGGTCGTACGGTTGATTTTCGTAACACCGTTGTGATCATGACATCAAACTTG
GGTTCCTCTCGAATCCAAGAGAACTTCGCCACATTGGACTATCAAGGTATCAAGAGTGAAGTGATGGATGTGGTTAGCAA
ACACTTCCGCCCAGAGTTCTTGAACCGTGTTGACGAAATAGTGGTATTCCACCCACTTGGTCAAGAGCACATTAAGTCCA
TTGCTTCTATTCAATTAGAACGCTTGGCAAAACGACTAGAAGAAAAAGGGTATCAATTGGAGGTGTCTGATAAAGCACTC
GACTTGATCGCCCAAGTCGGTTTCGACCCAGTATACGGTGCACGTCCTTTAAAACGTGCAATTCAACAGAATGTCGAGAA
CCCATTAGCTAAATCCATTCTTGCTGGTGAAATAGTTCCAGACAAGAAAGTGCAGCTAATCGTTACTAATGACCAAATTC
TCGCTCATCAGTAA

Domains

Predicted by InterProScan.

• AAA lid domain (AAA_lid_9) (342-444)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (17-68)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (94-145)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (766-845)

• AAA domain (Cdc48 subfamily) (AAA_2) (596-760)

• ATPase family associated with various cellular activities (AAA) (AAA) (204-320)

3D structure

• AlphaFold DB: Q87S63

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Bacillus subtilis subsp. subtilis str. 168	46.597	100	0.471
clpE	Streptococcus mutans UA159	49.115	79.113	0.389
clpE	Streptococcus pneumoniae Rx1	47.701	81.214	0.387
clpE	Streptococcus pneumoniae D39	47.701	81.214	0.387
clpE	Streptococcus pneumoniae R6	47.701	81.214	0.387
clpC	Lactococcus lactis subsp. cremoris KW2	46.965	80.747	0.379