Detailed information    

insolico Bioinformatically predicted

Overview

Name   mutS/mutS2   Type   Machinery gene
Locus tag   IGS65_RS09130 Genome accession   NZ_CP066294
Coordinates   1878511..1880841 (+) Length   776 a.a.
NCBI ID   WP_019314199.1    Uniprot ID   -
Organism   Streptococcus mutans strain 27-3     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1873511..1885841
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  IGS65_RS09110 (IGS65_009110) lepB 1875882..1876469 (-) 588 WP_002263358.1 signal peptidase I -
  IGS65_RS09115 (IGS65_009115) rnhC 1876489..1877400 (-) 912 WP_192072396.1 ribonuclease HIII -
  IGS65_RS09120 (IGS65_009120) - 1877596..1877901 (+) 306 WP_002263360.1 hypothetical protein -
  IGS65_RS09125 (IGS65_009125) - 1877898..1878443 (+) 546 WP_002263361.1 CvpA family protein -
  IGS65_RS09130 (IGS65_009130) mutS/mutS2 1878511..1880841 (+) 2331 WP_019314199.1 endonuclease MutS2 Machinery gene
  IGS65_RS09135 (IGS65_009135) trxA 1880916..1881230 (+) 315 WP_002263363.1 thioredoxin -
  IGS65_RS09140 (IGS65_009140) - 1881328..1882377 (+) 1050 WP_192072395.1 zinc-dependent alcohol dehydrogenase family protein -
  IGS65_RS09145 (IGS65_009145) mutY 1882569..1883714 (-) 1146 WP_002264191.1 A/G-specific adenine glycosylase -
  IGS65_RS09150 (IGS65_009150) - 1885265..1885510 (+) 246 WP_002276385.1 hypothetical protein -

Sequence

Protein


Download         Length: 776 a.a.        Molecular weight: 87633.95 Da        Isoelectric Point: 6.5927

>NTDB_id=454643 IGS65_RS09130 WP_019314199.1 1878511..1880841(+) (mutS/mutS2) [Streptococcus mutans strain 27-3]
MNTKILKALEFDKVKKQFAHFLQSEQGQMELNDLLPMTNQEKIERSFAEIADVAQIFQEYASFGFGHSQDISESLRRLEL
GADLNTQELLAVKRILQMSAELKDFYDNLENVDLQILDCLFEKIETFPDLQGSLQAINDGGFIEDFASPELTKIRHHIHQ
NEQQIRQILQEMLKKQGDLLAENLIASRSGRSVLPVKNTYRHRIAGVVHDISASGNTVYIEPRAVVNLNEEMTQARADER
HEMTRILHDLSDRLRSQTDIIGNNAWLLGHIDFVRGKYLYMRENQASLPSLTTDQTIRLLSVRHPLLSNPIANDLHFEHD
TTAILITGPNTGGKTIMLKTLGITQLMAQSGLPILADEGSKVAVFKDIFADIGDEQSIEQSLSTFSSHMTHIVEILQKAN
KDSLVLFDELGAGTDPQEGAALAMSILEHLRLSDIKTMITTHYPELKAYGIETEFIENASMEFDMVTLSPTYHFMQGVPG
RSNAFEIARRLGLSEIIVAAAENLTNTDSDVNKIIERLENQTIESRRRLDNIREVEQENLKFNRAVKKLYNEFSHAQDKE
LRKAKLKAQEIVDKALAESDFILKNLQDKAQLKPHEIIEAKGKLKQLAPEIELSKNKVLKKAKKKRAAKVGDDIIVSSYG
QRGTLTKRFKDGRWEAQVGLIKMTLQESEFDLVKSDKAQASQKRQAHLVKRTSQKAPSARLDLRGKRYEEAMQELDEFID
QALLNNMAQVDIIHGIGTGVIRDGVTKYLRRNKQVKEFGYAPQNAGGSGATIVTFK

Nucleotide


Download         Length: 2331 bp        

>NTDB_id=454643 IGS65_RS09130 WP_019314199.1 1878511..1880841(+) (mutS/mutS2) [Streptococcus mutans strain 27-3]
ATGAATACAAAGATTTTAAAAGCCTTAGAATTTGATAAGGTTAAAAAGCAATTTGCTCATTTTTTGCAGAGTGAGCAAGG
GCAAATGGAATTAAACGATTTATTACCTATGACCAATCAGGAAAAAATTGAACGTTCTTTTGCTGAAATTGCAGATGTAG
CACAGATTTTTCAGGAGTATGCTTCCTTTGGCTTTGGGCACAGTCAGGATATTTCAGAAAGTTTACGTCGTTTAGAATTA
GGAGCGGATCTCAATACTCAAGAGCTTTTGGCTGTCAAACGTATTTTGCAGATGTCAGCAGAGCTCAAGGACTTTTATGA
TAATTTAGAAAATGTTGATTTACAAATTTTGGATTGCTTATTTGAAAAGATTGAAACGTTTCCTGATTTGCAAGGGAGTT
TACAAGCCATCAATGATGGTGGCTTTATTGAAGATTTTGCTAGTCCTGAATTAACTAAAATTCGTCATCATATTCACCAA
AATGAACAACAAATTCGTCAAATTCTTCAGGAAATGTTGAAGAAACAAGGTGATTTATTGGCTGAAAACCTTATTGCCAG
TCGCAGTGGTCGCAGTGTTCTTCCAGTGAAAAATACTTATCGTCATCGTATTGCAGGTGTTGTTCATGATATTTCAGCTT
CAGGAAATACGGTTTACATTGAACCTCGAGCTGTTGTTAATTTAAATGAAGAGATGACTCAGGCGCGTGCAGACGAACGC
CATGAAATGACTCGCATTTTACATGATTTATCCGATAGGCTAAGATCACAAACAGATATTATTGGTAATAATGCTTGGTT
GCTTGGACATATTGATTTTGTTCGTGGGAAATACCTTTATATGAGAGAAAATCAAGCCAGTCTTCCTAGTTTAACAACGG
ATCAAACTATCCGTCTTTTGAGTGTACGTCATCCTCTGCTAAGCAATCCAATTGCCAATGATTTACATTTTGAACATGAT
ACAACAGCCATTTTAATTACAGGTCCTAATACGGGCGGTAAAACCATCATGTTAAAAACATTGGGAATAACGCAACTGAT
GGCTCAGTCAGGTCTTCCTATTTTGGCTGATGAGGGAAGTAAGGTTGCTGTTTTTAAAGACATCTTTGCAGACATTGGTG
ATGAACAGTCCATTGAGCAAAGTTTATCCACTTTTTCAAGTCATATGACACATATTGTCGAAATTCTGCAAAAGGCTAAT
AAAGACAGCTTAGTCCTTTTTGATGAACTTGGTGCTGGTACGGATCCACAAGAAGGGGCAGCCTTGGCCATGAGTATTCT
GGAACATTTACGCTTATCAGATATTAAAACAATGATTACCACCCATTATCCAGAGCTCAAGGCCTATGGTATCGAAACAG
AATTTATTGAAAATGCGAGTATGGAATTTGATATGGTGACGCTCAGCCCCACCTATCATTTTATGCAAGGAGTACCGGGA
CGATCCAATGCTTTTGAGATTGCACGTCGTTTAGGTTTGTCTGAAATTATTGTTGCAGCAGCGGAAAATTTGACGAATAC
GGATTCAGATGTTAATAAAATTATTGAACGTTTGGAAAATCAAACCATTGAAAGTCGCAGACGTTTGGATAATATTCGTG
AAGTGGAGCAGGAAAATCTCAAATTTAATCGAGCCGTCAAAAAACTTTATAATGAATTCTCACATGCACAAGACAAAGAG
TTGCGTAAGGCCAAACTAAAGGCTCAAGAGATTGTTGACAAGGCTCTTGCAGAGAGTGATTTTATTCTCAAAAATCTTCA
AGACAAAGCACAACTTAAGCCCCATGAAATTATTGAAGCTAAAGGCAAGCTCAAGCAGTTGGCTCCCGAGATAGAGCTTT
CGAAAAATAAGGTTCTTAAAAAAGCTAAGAAGAAACGTGCTGCGAAAGTTGGAGATGATATTATTGTCAGCAGTTATGGG
CAAAGAGGAACGCTTACTAAGCGCTTCAAAGATGGTCGTTGGGAAGCACAAGTAGGGCTGATCAAAATGACTTTACAAGA
GTCAGAGTTTGATTTAGTGAAATCAGACAAAGCCCAAGCATCGCAGAAAAGACAAGCTCACCTTGTCAAAAGGACTTCTC
AAAAGGCTCCTAGTGCTAGACTTGATTTACGTGGCAAGCGTTATGAAGAAGCGATGCAAGAATTAGATGAATTCATTGAT
CAGGCACTCTTGAACAATATGGCTCAGGTTGACATCATCCATGGTATAGGAACTGGTGTTATCCGTGATGGCGTAACTAA
ATATCTTCGCCGTAATAAGCAAGTTAAGGAGTTTGGCTATGCTCCTCAAAATGCAGGTGGTTCGGGCGCTACAATCGTGA
CTTTCAAATAG

Domains

Predicted by InterProScan.

MutS domain V (MutS_V)

(324-505)

Smr domain (Smr)

(701-776)

MutS2 and Smr-associated SH3 domain (MSSS)

(630-669)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mutS/mutS2 Bacillus subtilis subsp. subtilis str. 168

39.975

100

0.406