Detailed information    

insolico Bioinformatically predicted

Overview

Name   mutS/mutS2   Type   Machinery gene
Locus tag   I6H74_RS03260 Genome accession   NZ_CP066069
Coordinates   638908..641244 (+) Length   778 a.a.
NCBI ID   WP_014612575.1    Uniprot ID   -
Organism   Streptococcus dysgalactiae strain FDAARGOS_1017     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 633908..646244
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6H74_RS03240 (I6H74_03235) lepB 636233..636826 (-) 594 WP_002983074.1 signal peptidase I -
  I6H74_RS03245 (I6H74_03240) rnhC 636837..637739 (-) 903 WP_115257009.1 ribonuclease HIII -
  I6H74_RS03250 (I6H74_03245) - 637896..638204 (+) 309 WP_003052702.1 hypothetical protein -
  I6H74_RS03255 (I6H74_03250) - 638207..638752 (+) 546 WP_003056838.1 CvpA family protein -
  I6H74_RS03260 (I6H74_03255) mutS/mutS2 638908..641244 (+) 2337 WP_014612575.1 endonuclease MutS2 Machinery gene
  I6H74_RS03265 (I6H74_03260) - 641337..642656 (-) 1320 WP_115257008.1 FAD-containing oxidoreductase -
  I6H74_RS03270 (I6H74_03265) trxA 642883..643197 (+) 315 WP_003052691.1 thioredoxin -
  I6H74_RS03275 (I6H74_03270) - 643289..644637 (+) 1349 WP_111678988.1 IS3 family transposase -
  I6H74_RS03280 (I6H74_03275) mutY 644684..645850 (-) 1167 WP_115257109.1 A/G-specific adenine glycosylase -

Sequence

Protein


Download         Length: 778 a.a.        Molecular weight: 87077.66 Da        Isoelectric Point: 6.7996

>NTDB_id=453538 I6H74_RS03260 WP_014612575.1 638908..641244(+) (mutS/mutS2) [Streptococcus dysgalactiae strain FDAARGOS_1017]
MDKKILEQLEFDKVKEQFRAYLQTEQGNRELDQLEPLNHHDKIKHYFLEIEEMAGIFVEQHHFALGSLSDISASMRRLEL
EADLSIPELLAVKKILQVSAEASRFYVDLENVQLQALKRLFENLELFPSLQGSLQAINDGGFVESFASPELEKIRRSISD
KEHASRNVLQDLLKKQGDYLSESLIASRNGRSVLPVKNTFRNKVAGVVHDISASGNTVYIEPRALVQLNEELTQLQADER
HEVSRVLQALSDLIRPHSRALTNNAWILGHLDFIRAKYLYMRDNKATVPAISDDKSLQLLNVRHPLLQEPVANDLHFSKD
LAVIVITGPNTGGKTIMLKTLGLAQLMAQSGLPILADKGSKVAVFSGIFADIGDEQSIEQSLSTFSSHMTHIVAILNQAD
ADSLVLFDELGAGTDPQEGASLAMAILEQLRLTNIKTMATTHYPELKAYGIETPYVENASMEFDSMSLKPTYRFMQGVPG
RSNAFEIARRLGLAEHIVKEAQNMTDTDSDVNRIIEQLEKQTLESRKRLDHIREVEQDNLKFNRAVKKLYNEFSQAKDKE
IEKATLEAREIVDLALAESDSILNQLHDKAALKPHEVIEAKGQLKQLVPEKSLSQNKVLKKAKQLRAPRVGDDIIVTAYG
QRGTLVKELKDKKWEAQVGLIKMTLKEDEFSLVKVVEEVQKPKKKAINVVKKAATGGGPRARLDLRGKRYEEAMQELDAF
IDQALLNNMSQVDIIHGIGTGVIREAVTKYLRRNKHVKSFGYAPQNAGGSGCTIANLG

Nucleotide


Download         Length: 2337 bp        

>NTDB_id=453538 I6H74_RS03260 WP_014612575.1 638908..641244(+) (mutS/mutS2) [Streptococcus dysgalactiae strain FDAARGOS_1017]
ATGGATAAAAAGATTTTAGAACAGTTAGAATTTGATAAGGTCAAAGAACAATTTCGGGCCTACCTGCAGACAGAGCAGGG
GAACCGTGAATTAGACCAACTTGAACCCCTCAATCATCATGACAAAATCAAACATTACTTTTTAGAAATTGAAGAGATGG
CTGGCATTTTTGTAGAGCAACATCACTTTGCATTGGGCAGTCTGTCTGACATTTCAGCTAGCATGAGACGTTTGGAACTG
GAAGCTGATTTGAGCATTCCCGAATTATTAGCAGTCAAAAAAATACTTCAGGTATCAGCAGAAGCGAGTCGCTTTTATGT
TGATTTGGAAAACGTTCAGCTGCAAGCCTTGAAGCGTTTGTTTGAAAATCTGGAGCTTTTTCCTAGCCTTCAAGGCAGTC
TTCAGGCTATTAATGACGGTGGTTTTGTGGAAAGTTTTGCCAGTCCCGAGTTAGAAAAAATTCGTCGTAGCATCTCAGAC
AAAGAACATGCGAGCCGGAATGTCTTACAAGATTTACTCAAAAAGCAAGGTGACTATTTGTCAGAAAGCTTGATTGCTAG
CCGAAACGGGCGTAGTGTCTTACCTGTCAAAAACACTTTCCGTAATAAGGTGGCAGGGGTCGTTCACGATATTTCGGCTT
CAGGAAATACGGTTTATATTGAACCACGAGCTCTTGTTCAACTAAATGAAGAGCTGACGCAGTTACAAGCCGACGAACGC
CATGAAGTGTCACGTGTCCTTCAAGCCTTATCTGACCTCATCAGACCTCATAGTCGAGCTCTTACCAATAATGCTTGGAT
TCTGGGGCATCTGGATTTTATCAGAGCCAAATACCTCTATATGAGAGACAATAAGGCCACGGTCCCGGCTATTTCGGATG
ATAAAAGTTTACAGTTGTTAAATGTGCGCCACCCTCTTTTGCAGGAGCCAGTTGCTAATGATTTGCATTTCTCTAAAGAT
TTGGCTGTTATTGTGATTACTGGTCCGAATACTGGTGGTAAAACCATCATGCTAAAAACACTTGGTTTAGCCCAGCTAAT
GGCCCAATCGGGTCTGCCTATTCTAGCAGATAAAGGTTCCAAAGTTGCTGTTTTTAGTGGTATTTTTGCTGATATTGGCG
ATGAACAATCCATTGAGCAGAGCTTATCAACTTTCTCTAGCCATATGACTCATATTGTTGCTATTTTGAATCAAGCTGAT
GCAGACAGTTTAGTACTCTTTGATGAGCTAGGGGCAGGAACAGATCCGCAAGAAGGAGCAAGTCTTGCTATGGCAATCTT
GGAGCAGTTACGCTTAACTAATATCAAAACCATGGCGACTACCCATTACCCTGAACTAAAAGCATATGGCATCGAAACTC
CCTATGTGGAAAATGCCAGTATGGAGTTCGATAGCATGAGTTTAAAACCAACTTACCGCTTTATGCAGGGAGTTCCAGGT
CGTTCAAATGCCTTTGAAATTGCTAGACGCCTTGGGTTGGCAGAGCACATTGTCAAAGAAGCTCAAAACATGACAGACAC
AGATAGTGATGTTAACCGTATTATCGAACAGTTAGAGAAACAAACTCTGGAGAGTCGTAAGCGGCTTGATCATATTCGAG
AAGTGGAGCAAGATAACCTCAAATTTAACCGTGCGGTTAAAAAATTGTACAATGAGTTCTCACAGGCCAAAGATAAGGAA
ATTGAAAAAGCTACCCTTGAAGCGCGTGAGATCGTAGACTTAGCTTTAGCAGAAAGTGACAGTATTTTAAACCAGTTGCA
TGACAAAGCTGCACTTAAACCTCACGAAGTTATTGAAGCCAAGGGGCAACTCAAACAGTTAGTGCCAGAAAAGAGTCTTT
CTCAAAACAAGGTCCTAAAGAAAGCGAAGCAATTACGAGCTCCTCGAGTAGGAGACGATATTATTGTAACAGCCTATGGC
CAAAGAGGAACCTTGGTAAAAGAACTCAAAGATAAGAAGTGGGAAGCGCAAGTTGGACTGATCAAAATGACCCTCAAAGA
AGATGAATTTAGTCTTGTGAAGGTTGTTGAGGAAGTTCAAAAACCAAAGAAAAAAGCCATCAACGTGGTCAAGAAGGCTG
CTACTGGTGGTGGTCCTCGTGCCCGTCTGGATTTGCGTGGCAAACGGTATGAAGAAGCGATGCAAGAACTAGACGCCTTT
ATTGACCAAGCTCTCTTAAATAATATGAGCCAAGTGGATATTATTCATGGGATTGGCACTGGTGTAATCCGTGAAGCTGT
TACCAAATACCTCAGACGAAACAAACATGTTAAAAGCTTTGGTTATGCTCCACAGAATGCGGGTGGATCAGGGTGTACCA
TTGCGAACTTAGGTTGA

Domains

Predicted by InterProScan.

Smr domain (Smr)

(703-776)

MutS2 and Smr-associated SH3 domain (MSSS)

(630-669)

MutS domain V (MutS_V)

(324-505)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mutS/mutS2 Bacillus subtilis subsp. subtilis str. 168

40.506

100

0.411