Detailed information NTG0453499

Bioinformatically predicted

Overview

• Name: endA
• Type: Machinery gene
• Locus tag: FOC72_RS06380
• Genome accession: NZ_CP054570
• Coordinates: 1344233..1345093 (-)
• Length: 286 a.a.
• NCBI ID: WP_002895987.1
• Uniprot ID: -
• Organism: Streptococcus sanguinis strain FDAARGOS_770
• Function: cleavage of dsDNA into ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1339233..1350093

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FOC72_RS06360 (FOC72_06360)	-	1339279..1340949 (-)	1671	WP_174606303.1	DUF2971 domain-containing protein	-
FOC72_RS06365 (FOC72_06365)	-	1340971..1342866 (-)	1896	WP_032914202.1	ABC-F family ATP-binding cassette domain-containing protein	-
FOC72_RS06370 (FOC72_06370)	-	1342966..1343331 (-)	366	WP_002895985.1	hypothetical protein	-
FOC72_RS06375 (FOC72_06375)	-	1343336..1344055 (-)	720	WP_032914204.1	matrixin family metalloprotease	-
FOC72_RS06380 (FOC72_06380)	endA	1344233..1345093 (-)	861	WP_002895987.1	DNA/RNA non-specific endonuclease	Machinery gene
FOC72_RS06385 (FOC72_06385)	-	1345152..1345334 (-)	183	WP_002895988.1	DNA-directed RNA polymerase subunit beta	-
FOC72_RS06390 (FOC72_06390)	murA	1345327..1346607 (-)	1281	WP_002895989.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
FOC72_RS06395 (FOC72_06395)	-	1346675..1346905 (-)	231	WP_002895990.1	DUF1146 family protein	-
FOC72_RS06400 (FOC72_06400)	-	1347079..1347501 (-)	423	WP_002895991.1	F0F1 ATP synthase subunit epsilon	-
FOC72_RS06405 (FOC72_06405)	atpD	1347509..1348915 (-)	1407	WP_002895993.1	F0F1 ATP synthase subunit beta	-
FOC72_RS06410 (FOC72_06410)	-	1348954..1349835 (-)	882	WP_002895995.1	F0F1 ATP synthase subunit gamma	-

Sequence

Protein

• Length: 286 a.a.
• Molecular weight: 31214.86 Da
• Isoelectric Point: 9.9817

>NTDB_id=453499 FOC72_RS06380 WP_002895987.1 1344233..1345093(-) (endA) [Streptococcus sanguinis strain FDAARGOS_770]
MKRKTSQKRNSKSLQGWAGLTLALILALAGYFWGQDGQQPLQSPNSEIRVGQVQDQGTPSRELAESVLTDAVRAQLKGSI
EWNGAGAFIVNGNKTDLDAGISSKPYADNKTKLVQGQTLPTVANAFLSKSTRQYKKREETGNANTSWVPAGWHQLKNLPG
EYNHAVDRGHLLAYSLIGGLKGFDASTSNPANIAVQTAWSNQANEADSTGQNYYETKIRKALDKNKRVRYRVTLIYATET
DLVPVGSHLEAKSSDGSLEFNVFIPNVQKGIRLDYNSGRVSLDTGS

Nucleotide

• Length: 861 bp

>NTDB_id=453499 FOC72_RS06380 WP_002895987.1 1344233..1345093(-) (endA) [Streptococcus sanguinis strain FDAARGOS_770]
ATGAAAAGAAAGACTAGTCAGAAAAGGAATTCTAAGAGCCTGCAAGGCTGGGCTGGGCTGACTCTGGCCTTGATTTTGGC
GCTGGCTGGCTATTTCTGGGGACAGGATGGTCAGCAGCCACTTCAGAGTCCAAATTCAGAAATAAGAGTTGGGCAAGTTC
AAGATCAGGGCACCCCTAGTCGGGAACTGGCTGAGAGCGTTCTGACGGATGCTGTCCGAGCTCAACTCAAAGGCAGCATT
GAATGGAATGGAGCTGGCGCCTTTATTGTGAATGGAAATAAGACAGACTTGGATGCGGGGATTTCTAGTAAGCCCTACGC
TGACAATAAGACCAAGCTTGTACAAGGGCAAACCCTTCCGACAGTAGCGAATGCCTTTTTATCCAAGTCTACCCGCCAGT
ACAAAAAACGGGAAGAAACTGGAAATGCCAACACTTCATGGGTACCGGCAGGCTGGCATCAACTCAAGAACCTCCCTGGT
GAGTACAATCATGCTGTGGACAGAGGACATCTCTTGGCCTATTCGCTGATTGGTGGTTTGAAGGGCTTTGATGCTTCTAC
TAGCAATCCTGCCAATATCGCTGTGCAGACGGCCTGGTCCAACCAAGCCAATGAAGCGGATTCGACAGGGCAGAATTATT
ATGAGACAAAGATCCGTAAGGCTTTGGATAAGAACAAGCGAGTGCGCTACCGGGTAACCTTGATTTATGCCACGGAGACT
GATTTAGTACCGGTTGGGTCACATTTAGAGGCCAAGTCCAGCGATGGCAGTTTAGAATTTAATGTCTTTATCCCGAATGT
GCAAAAAGGGATTCGCCTGGACTATAATAGTGGCAGGGTCAGTCTGGATACGGGTTCTTAA

Domains

Predicted by InterproScan.

• DNA/RNA non-specific endonuclease (Endonuclease_NS) (88-256)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
endA	Streptococcus pneumoniae Rx1	74.554	78.322	0.584
endA	Streptococcus pneumoniae D39	74.554	78.322	0.584
endA	Streptococcus pneumoniae R6	74.554	78.322	0.584
endA	Streptococcus pneumoniae TIGR4	74.554	78.322	0.584