Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   HSZ47_RS04365 Genome accession   NZ_CP054434
Coordinates   915186..915902 (-) Length   238 a.a.
NCBI ID   WP_002482781.1    Uniprot ID   A0A380HJP0
Organism   Staphylococcus saprophyticus strain UTI-035     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 910186..920902
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HSZ47_RS04345 (HSZ47_04345) - 911251..911475 (+) 225 WP_002482777.1 sulfurtransferase TusA family protein -
  HSZ47_RS04350 (HSZ47_04350) - 911621..912574 (+) 954 WP_011302725.1 LacI family DNA-binding transcriptional regulator -
  HSZ47_RS04355 (HSZ47_04355) - 912660..914144 (+) 1485 WP_011302726.1 sucrose-6-phosphate hydrolase -
  HSZ47_RS04360 (HSZ47_04360) - 914141..915109 (+) 969 WP_048787269.1 carbohydrate kinase -
  HSZ47_RS04365 (HSZ47_04365) agrA 915186..915902 (-) 717 WP_002482781.1 quorum-sensing response regulator AgrA Regulator
  HSZ47_RS04370 (HSZ47_04370) agrC 915915..917210 (-) 1296 WP_011302728.1 quorum-sensing sensor histidine kinase AgrC -
  HSZ47_RS04375 (HSZ47_04375) agrD 917236..917397 (-) 162 WP_002482783.1 cyclic lactone autoinducer peptide AgrD -
  HSZ47_RS04380 (HSZ47_04380) - 917400..917969 (-) 570 WP_011302729.1 accessory gene regulator AgrB -
  HSZ47_RS04385 (HSZ47_04385) - 918728..919513 (-) 786 WP_011302730.1 carbon-nitrogen family hydrolase -
  HSZ47_RS04390 (HSZ47_04390) - 919684..920313 (-) 630 WP_002482786.1 nitroreductase family protein -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27954.74 Da        Isoelectric Point: 5.0875

>NTDB_id=452450 HSZ47_RS04365 WP_002482781.1 915186..915902(-) (agrA) [Staphylococcus saprophyticus strain UTI-035]
MKIFICEDDERQREHMVSIINNYIMIEEKPMEIEVATADPYDILERSKNLNDIGCYFLDIQLEADINGIKLASEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPDELKSRIIDCLETSESRLKLLSKESSVETIELKRGSNSIYVQYDDVM
FFESSTKSHRLIAHLDNRQIEFYGNLKELDQLDERFFRCHNSFVVNRHNIDSIDSKSRVVYFKNNEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=452450 HSZ47_RS04365 WP_002482781.1 915186..915902(-) (agrA) [Staphylococcus saprophyticus strain UTI-035]
ATGAAAATATTCATTTGTGAAGATGATGAAAGACAACGTGAGCACATGGTTTCTATTATTAATAACTACATCATGATTGA
AGAAAAGCCAATGGAAATCGAAGTTGCTACTGCTGATCCTTATGACATCTTAGAACGCTCTAAGAACCTCAATGATATTG
GGTGTTATTTTTTAGATATTCAGCTTGAAGCTGATATTAATGGTATCAAACTTGCTAGTGAGATTCGTAAACATGATCCT
GTAGGTAATATCATCTTTGTTACAAGTCACAGTGAGTTAACTTACCTAACATTTGTCTATAAGGTAGCCGCGATGGATTT
CATTTTTAAAGATGATCCAGATGAATTAAAATCAAGAATTATTGACTGTCTTGAAACTTCAGAATCAAGATTGAAGCTTC
TTTCAAAAGAAAGTAGTGTTGAAACAATTGAATTAAAACGTGGAAGTAATTCGATTTATGTCCAATATGATGATGTTATG
TTCTTTGAATCATCTACTAAATCGCATCGATTGATTGCACATCTTGATAATCGTCAAATTGAGTTTTATGGCAATTTAAA
AGAATTAGATCAACTTGATGAGCGATTTTTCAGATGTCATAATAGCTTTGTCGTCAATAGACACAATATAGATTCTATTG
ACTCTAAGTCACGTGTTGTCTATTTTAAAAATAATGAACATTGCTATGCATCTGTTAGAAATGTCAAAAAAATATAA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(151-237)

Response regulator receiver domain (Response_reg)

(3-120)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A380HJP0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

85.714

100

0.857