Detailed information NTG0045240

Bioinformatically predicted

Overview

• Name: codY
• Type: Regulator
• Locus tag: SDSE_RS19600
• Genome accession: NC_019042
• Coordinates: 1830854..1831636 (-)
• Length: 260 a.a.
• NCBI ID: WP_003053880.1
• Uniprot ID: A0A9X9SKT8
• Organism: Streptococcus dysgalactiae subsp. equisimilis AC-2713
• Function: repress the expression of comX (predicted from homology) Competence regulation

Genomic Context

Location: 1825854..1836636

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SDSE_RS19570 (S_dysgal_equisimilis_AC2713_1892)	-	1826500..1827093 (-)	594	WP_274047907.1	helix-turn-helix transcriptional regulator	-
SDSE_RS19575 (S_dysgal_equisimilis_AC2713_1893)	-	1827324..1827623 (-)	300	WP_015058017.1	rhodanese-like domain-containing protein	-
SDSE_RS19580 (S_dysgal_equisimilis_AC2713_1894)	-	1827616..1829268 (-)	1653	WP_015058018.1	FAD-dependent oxidoreductase	-
SDSE_RS19585 (S_dysgal_equisimilis_AC2713_1895)	-	1829286..1829624 (-)	339	WP_003061685.1	rhodanese-like domain-containing protein	-
SDSE_RS19590 (S_dysgal_equisimilis_AC2713_1896)	-	1829838..1830098 (+)	261	WP_003053835.1	metal-sensitive transcriptional regulator	-
SDSE_RS19595 (S_dysgal_equisimilis_AC2713_1897)	-	1830165..1830716 (-)	552	WP_170172089.1	isochorismatase family cysteine hydrolase	-
SDSE_RS19600 (S_dysgal_equisimilis_AC2713_1898)	codY	1830854..1831636 (-)	783	WP_003053880.1	GTP-sensing pleiotropic transcriptional regulator CodY	Regulator
SDSE_RS19605 (S_dysgal_equisimilis_AC2713_1899)	-	1831901..1833115 (-)	1215	WP_003060547.1	pyridoxal phosphate-dependent aminotransferase	-
SDSE_RS19610 (S_dysgal_equisimilis_AC2713_1900)	-	1833452..1833904 (+)	453	WP_003052566.1	universal stress protein	-
SDSE_RS19615 (S_dysgal_equisimilis_AC2713_1901)	-	1834067..1835455 (-)	1389	WP_003052568.1	Cof-type HAD-IIB family hydrolase	-
SDSE_RS19620 (S_dysgal_equisimilis_AC2713_1902)	-	1835528..1836493 (+)	966	WP_003053845.1	asparaginase	-

Sequence

Protein

• Length: 260 a.a.
• Molecular weight: 28748.89 Da
• Isoelectric Point: 4.4678

>NTDB_id=45240 SDSE_RS19600 WP_003053880.1 1830854..1831636(-) (codY) [Streptococcus dysgalactiae subsp. equisimilis AC-2713]
MPNLLEKTRKITSILQRSVDSLETELPYNTMASRLADIIDCNACIINGGGTLLGYAMKYKTNTDRVEEFFEAKQFPDTYV
KAASRVYDTEANLSVESELTIFPVESKDIYPDGLTTIAPIYGGGMRLGSLIIWRNDNEFSDEDLILVEISSTVVGIQLLN
LQTENLEETIRKQTAVNMAINTLSYSEMKAVAAILGELDGNEGRLTASVIADRIGITRSVIVNALRKLESAGIIESRSLG
MKGTYLKVINEGIFDKLKEF

Nucleotide

• Length: 783 bp

>NTDB_id=45240 SDSE_RS19600 WP_003053880.1 1830854..1831636(-) (codY) [Streptococcus dysgalactiae subsp. equisimilis AC-2713]
ATGCCTAACTTATTAGAAAAAACTCGTAAAATTACGTCTATTCTACAGCGCTCTGTAGATAGCTTGGAGACAGAACTCCC
ATATAATACGATGGCGTCTCGCTTGGCAGATATTATTGACTGTAATGCCTGCATTATCAATGGCGGAGGAACCCTACTTG
GTTATGCCATGAAATATAAAACCAACACAGACCGTGTTGAGGAATTTTTTGAAGCTAAGCAATTTCCAGATACTTATGTC
AAAGCAGCTAGCCGTGTCTACGACACTGAGGCCAATCTTTCAGTGGAAAGTGAATTAACCATTTTTCCTGTGGAATCGAA
AGACATCTATCCAGATGGTTTGACAACAATTGCACCGATTTATGGTGGAGGTATGCGTCTAGGATCTCTTATCATTTGGC
GCAACGATAATGAGTTTAGTGATGAGGACCTCATCTTGGTTGAAATTTCAAGCACGGTTGTTGGGATTCAGTTGTTAAAC
CTTCAAACAGAAAACCTGGAAGAAACGATCCGCAAGCAAACTGCTGTCAACATGGCTATTAACACCCTATCTTATTCAGA
AATGAAGGCTGTTGCAGCTATTCTTGGTGAATTGGATGGTAACGAAGGGCGTTTAACAGCTTCTGTCATTGCTGACCGTA
TTGGCATTACACGATCTGTGATCGTCAATGCCCTTCGTAAATTGGAAAGTGCTGGTATTATTGAAAGTCGCTCTCTCGGC
ATGAAGGGAACCTACCTCAAAGTTATTAATGAGGGTATTTTTGATAAATTGAAAGAATTTTAA

Domains

Predicted by InterProScan.

• CodY helix-turn-helix domain (HTH_CodY) (202-260)

• CodY GAF-like domain (CodY) (3-182)

3D structure

• AlphaFold DB: A0A9X9SKT8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
codY	Lactococcus lactis subsp. lactis strain DGCC12653	66.537	98.846	0.658
codY	Bacillus subtilis subsp. subtilis str. 168	53.036	95	0.504