Detailed information    

insolico Bioinformatically predicted

Overview


Name   comGE   Type   Machinery gene
Locus tag   JAN99_RS00675 Genome accession   NZ_CP065927
Coordinates   104631..104915 (+) Length   94 a.a.
NCBI ID   WP_269460045.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain emm9ST603     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context


Location: 99631..109915
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JAN99_RS00650 (JAN99_00645) - 101577..101942 (+) 366 WP_002986560.1 DUF1033 family protein -
  JAN99_RS00655 (JAN99_00650) comGA 102035..102973 (+) 939 WP_002993471.1 competence type IV pilus ATPase ComGA Machinery gene
  JAN99_RS00660 (JAN99_00655) comGB 102909..103943 (+) 1035 WP_011054115.1 competence type IV pilus assembly protein ComGB Machinery gene
  JAN99_RS00665 (JAN99_00660) comGC 103945..104271 (+) 327 WP_002986552.1 competence type IV pilus major pilin ComGC Machinery gene
  JAN99_RS00670 (JAN99_00665) comGD 104246..104674 (+) 429 WP_002986548.1 competence type IV pilus minor pilin ComGD Machinery gene
  JAN99_RS00675 (JAN99_00670) comGE 104631..104915 (+) 285 WP_269460045.1 competence type IV pilus minor pilin ComGE Machinery gene
  JAN99_RS00680 (JAN99_00675) comGF 104908..105342 (+) 435 WP_002987783.1 competence type IV pilus minor pilin ComGF Machinery gene
  JAN99_RS00685 (JAN99_00680) comGG 105326..105652 (+) 327 WP_009880358.1 competence type IV pilus minor pilin ComGG -
  JAN99_RS00690 (JAN99_00685) comGH 105750..106703 (+) 954 WP_002987790.1 class I SAM-dependent methyltransferase Machinery gene
  JAN99_RS00695 (JAN99_00690) - 106762..107958 (+) 1197 WP_002987791.1 acetate kinase -
  JAN99_RS00700 (JAN99_00695) - 108145..108453 (+) 309 WP_010921804.1 hypothetical protein -
  JAN99_RS00705 (JAN99_00700) proC 108536..109306 (-) 771 WP_111692971.1 pyrroline-5-carboxylate reductase -

Sequence


Protein


Download         Length: 94 a.a.        Molecular weight: 10668.62 Da        Isoelectric Point: 8.9043

>NTDB_id=451990 JAN99_RS00675 WP_269460045.1 104631..104915(+) (comGE) [Streptococcus pyogenes strain emm9ST603]
MGIIKKQVKAYIALESMIATGILFSIVILILSSLQQSQAALTYYRKQQEKLNLALMAVQTRTKEITLNGCHITILRTDRY
ISIHDDEGEVMKIE

Nucleotide


Download         Length: 285 bp        

>NTDB_id=451990 JAN99_RS00675 WP_269460045.1 104631..104915(+) (comGE) [Streptococcus pyogenes strain emm9ST603]
GTGGGAATTATCAAAAAACAAGTCAAAGCTTACATAGCCCTTGAAAGTATGATCGCAACAGGCATCCTCTTTAGTATTGT
CATTCTCATCTTAAGCAGTTTACAGCAGAGTCAGGCTGCTCTAACGTACTATCGAAAGCAGCAAGAAAAGCTTAATCTAG
CCTTGATGGCAGTACAAACTAGAACTAAAGAGATAACATTGAATGGTTGTCATATTACTATTTTACGTACGGATAGATAC
ATTAGTATTCACGATGACGAAGGAGAAGTGATGAAGATTGAGTAA


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE Lactococcus lactis subsp. cremoris KW2

38.298

100

0.383

  comGE Streptococcus mutans UA140

36.559

98.936

0.362

  comGE Streptococcus mutans UA159

36.559

98.936

0.362