Detailed information    

insolico Bioinformatically predicted

Overview


Name   codY   Type   Regulator
Locus tag   FOC74_RS26560 Genome accession   NZ_CP053997
Coordinates   4738603..4739382 (+) Length   259 a.a.
NCBI ID   WP_000421288.1    Uniprot ID   Q81WK7
Organism   Bacillus cereus strain FDAARGOS_780     
Function   repression of comK (predicted from homology)   
Competence regulation

Related MGE


Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
ICE 4699779..4773704 4738603..4739382 within 0


Gene organization within MGE regions


Location: 4699779..4773704
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FOC74_RS26370 (FOC74_26370) rsmB 4699937..4701271 (+) 1335 WP_001249652.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  FOC74_RS26375 (FOC74_26375) rlmN 4701276..4702364 (+) 1089 WP_000450543.1 23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN -
  FOC74_RS26380 (FOC74_26380) - 4702369..4703121 (+) 753 WP_000648699.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  FOC74_RS26385 (FOC74_26385) prkC 4703130..4705103 (+) 1974 WP_000904759.1 serine/threonine protein kinase PrkC -
  FOC74_RS26390 (FOC74_26390) rsgA 4705372..4706253 (+) 882 WP_001113935.1 ribosome small subunit-dependent GTPase A -
  FOC74_RS26395 (FOC74_26395) rpe 4706256..4706900 (+) 645 WP_000589966.1 ribulose-phosphate 3-epimerase -
  FOC74_RS26400 (FOC74_26400) - 4707000..4707680 (+) 681 WP_033688055.1 thiamine diphosphokinase -
  FOC74_RS26405 (FOC74_26405) spoVM 4707747..4707827 (+) 81 WP_001213599.1 stage V sporulation protein SpoVM -
  FOC74_RS26410 (FOC74_26410) rpmB 4707901..4708089 (-) 189 WP_000124776.1 50S ribosomal protein L28 -
  FOC74_RS26415 (FOC74_26415) - 4708468..4708830 (+) 363 WP_000021109.1 Asp23/Gls24 family envelope stress response protein -
  FOC74_RS26420 (FOC74_26420) - 4708853..4710529 (+) 1677 WP_000027136.1 DAK2 domain-containing protein -
  FOC74_RS26425 (FOC74_26425) recG 4710819..4712867 (+) 2049 WP_001006884.1 ATP-dependent DNA helicase RecG -
  FOC74_RS26430 (FOC74_26430) fapR 4712956..4713549 (+) 594 WP_000747352.1 transcription factor FapR -
  FOC74_RS26435 (FOC74_26435) plsX 4713546..4714538 (+) 993 WP_000684108.1 phosphate acyltransferase PlsX -
  FOC74_RS26440 (FOC74_26440) fabD 4714553..4715497 (+) 945 WP_000516948.1 ACP S-malonyltransferase -
  FOC74_RS26445 (FOC74_26445) fabG 4715497..4716237 (+) 741 WP_000911782.1 3-oxoacyl-[acyl-carrier-protein] reductase -
  FOC74_RS26450 (FOC74_26450) acpP 4716307..4716540 (+) 234 WP_000786062.1 acyl carrier protein -
  FOC74_RS26455 (FOC74_26455) rncS 4716599..4717336 (+) 738 WP_001146873.1 ribonuclease III -
  FOC74_RS26460 (FOC74_26460) smc 4717483..4721052 (+) 3570 WP_000478986.1 chromosome segregation protein SMC -
  FOC74_RS26465 (FOC74_26465) ftsY 4721068..4722057 (+) 990 WP_000007651.1 signal recognition particle-docking protein FtsY -
  FOC74_RS26470 (FOC74_26470) - 4722191..4722523 (+) 333 WP_000891062.1 putative DNA-binding protein -
  FOC74_RS26475 (FOC74_26475) ffh 4722536..4723885 (+) 1350 WP_000863461.1 signal recognition particle protein -
  FOC74_RS26480 (FOC74_26480) rpsP 4723986..4724258 (+) 273 WP_000268750.1 30S ribosomal protein S16 -
  FOC74_RS26485 (FOC74_26485) - 4724273..4724500 (+) 228 WP_000737398.1 KH domain-containing protein -
  FOC74_RS26490 (FOC74_26490) rimM 4724621..4725136 (+) 516 WP_000170268.1 ribosome maturation factor RimM -
  FOC74_RS26495 (FOC74_26495) trmD 4725136..4725870 (+) 735 WP_000686892.1 tRNA (guanosine(37)-N1)-methyltransferase TrmD -
  FOC74_RS26500 (FOC74_26500) rplS 4726017..4726361 (+) 345 WP_001186516.1 50S ribosomal protein L19 -
  FOC74_RS26505 (FOC74_26505) lepB 4726463..4727014 (+) 552 WP_000711857.1 signal peptidase I -
  FOC74_RS26510 (FOC74_26510) ylqF 4727035..4727925 (+) 891 WP_000236696.1 ribosome biogenesis GTPase YlqF -
  FOC74_RS26515 (FOC74_26515) rnhB 4727977..4728750 (+) 774 WP_001174714.1 ribonuclease HII -
  FOC74_RS26520 (FOC74_26520) sucC 4728944..4730104 (+) 1161 WP_001020785.1 ADP-forming succinate--CoA ligase subunit beta -
  FOC74_RS26525 (FOC74_26525) sucD 4730124..4731026 (+) 903 WP_000115178.1 succinate--CoA ligase subunit alpha -
  FOC74_RS26530 (FOC74_26530) dprA 4731114..4731983 (+) 870 WP_000818033.1 DNA-processing protein DprA -
  FOC74_RS26535 (FOC74_26535) topA 4732128..4734206 (+) 2079 WP_001286969.1 type I DNA topoisomerase -
  FOC74_RS26540 (FOC74_26540) trmFO 4734257..4735561 (+) 1305 WP_001991958.1 FADH(2)-oxidizing methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))- methyltransferase TrmFO -
  FOC74_RS26545 (FOC74_26545) xerC 4735627..4736526 (+) 900 WP_001101227.1 tyrosine recombinase XerC -
  FOC74_RS26550 (FOC74_26550) hslV 4736569..4737111 (+) 543 WP_000526272.1 ATP-dependent protease proteolytic subunit HslV -
  FOC74_RS26555 (FOC74_26555) hslU 4737134..4738525 (+) 1392 WP_000550088.1 ATP-dependent protease ATPase subunit HslU -
  FOC74_RS26560 (FOC74_26560) codY 4738603..4739382 (+) 780 WP_000421288.1 GTP-sensing pleiotropic transcriptional regulator CodY Regulator
  FOC74_RS26565 (FOC74_26565) rpsB 4739733..4740434 (+) 702 WP_000111483.1 30S ribosomal protein S2 -
  FOC74_RS26570 (FOC74_26570) tsf 4740538..4741425 (+) 888 WP_001018581.1 translation elongation factor Ts -
  FOC74_RS26575 (FOC74_26575) pyrH 4741492..4742214 (+) 723 WP_000042663.1 UMP kinase -
  FOC74_RS26580 (FOC74_26580) frr 4742217..4742774 (+) 558 WP_000531503.1 ribosome recycling factor -
  FOC74_RS26585 (FOC74_26585) uppS 4742860..4743636 (+) 777 WP_000971301.1 isoprenyl transferase -
  FOC74_RS26590 (FOC74_26590) cdsA 4743654..4744445 (+) 792 WP_000813581.1 phosphatidate cytidylyltransferase -
  FOC74_RS26595 (FOC74_26595) dxr 4744469..4745611 (+) 1143 WP_000790359.1 1-deoxy-D-xylulose-5-phosphate reductoisomerase -
  FOC74_RS26600 (FOC74_26600) rseP 4745628..4746884 (+) 1257 WP_001090229.1 RIP metalloprotease RseP -
  FOC74_RS26605 (FOC74_26605) - 4746994..4748694 (+) 1701 WP_000814312.1 proline--tRNA ligase -
  FOC74_RS26610 (FOC74_26610) - 4748819..4753120 (+) 4302 WP_000059985.1 PolC-type DNA polymerase III -
  FOC74_RS26615 (FOC74_26615) rimP 4753453..4753923 (+) 471 WP_000359097.1 ribosome maturation factor RimP -
  FOC74_RS26620 (FOC74_26620) nusA 4753941..4755047 (+) 1107 WP_000102609.1 transcription termination factor NusA -
  FOC74_RS26625 (FOC74_26625) - 4755059..4755331 (+) 273 WP_000071128.1 YlxR family protein -
  FOC74_RS26630 (FOC74_26630) - 4755332..4755643 (+) 312 WP_001286523.1 YlxQ family RNA-binding protein -
  FOC74_RS26635 (FOC74_26635) infB 4755648..4757708 (+) 2061 WP_000036341.1 translation initiation factor IF-2 -
  FOC74_RS26640 (FOC74_26640) - 4757705..4757986 (+) 282 WP_000582364.1 DUF503 domain-containing protein -
  FOC74_RS26645 (FOC74_26645) rbfA 4758002..4758358 (+) 357 WP_000776441.1 30S ribosome-binding factor RbfA -
  FOC74_RS26650 (FOC74_26650) truB 4758445..4759368 (+) 924 WP_000399337.1 tRNA pseudouridine(55) synthase TruB -
  FOC74_RS26655 (FOC74_26655) ribF 4759412..4760383 (+) 972 WP_000766711.1 bifunctional riboflavin kinase/FAD synthetase -
  FOC74_RS26660 (FOC74_26660) rpsO 4760484..4760753 (+) 270 WP_001229392.1 30S ribosomal protein S15 -
  FOC74_RS26665 (FOC74_26665) pnp 4760914..4763052 (+) 2139 WP_000076750.1 polyribonucleotide nucleotidyltransferase -
  FOC74_RS26670 (FOC74_26670) - 4763204..4764103 (+) 900 WP_000647529.1 polysaccharide deacetylase family protein -
  FOC74_RS26675 (FOC74_26675) - 4764190..4765431 (+) 1242 WP_000592985.1 pitrilysin family protein -
  FOC74_RS26680 (FOC74_26680) - 4765558..4765809 (+) 252 WP_001239752.1 YlmC/YmxH family sporulation protein -
  FOC74_RS26685 (FOC74_26685) dpaA 4766084..4766986 (+) 903 WP_000954728.1 dipicolinic acid synthetase subunit A -
  FOC74_RS26690 (FOC74_26690) dpaB 4766983..4767582 (+) 600 WP_001049484.1 dipicolinate synthase subunit B -
  FOC74_RS26695 (FOC74_26695) asd 4767733..4768779 (+) 1047 WP_000414849.1 aspartate-semialdehyde dehydrogenase -
  FOC74_RS26700 (FOC74_26700) dapG 4768803..4770035 (+) 1233 WP_000692470.1 aspartate kinase -
  FOC74_RS26705 (FOC74_26705) dapA 4770047..4770925 (+) 879 WP_000564761.1 4-hydroxy-tetrahydrodipicolinate synthase -
  FOC74_RS26710 (FOC74_26710) - 4771691..4773361 (+) 1671 WP_000823085.1 ribonuclease J -

Sequence


Protein


Download         Length: 259 a.a.        Molecular weight: 28774.05 Da        Isoelectric Point: 4.7947

>NTDB_id=449910 FOC74_RS26560 WP_000421288.1 4738603..4739382(+) (codY) [Bacillus cereus strain FDAARGOS_780]
MELLAKTRKLNALLQSAAGKPVNFREMSDTMCEVIEANVFVVSRRGKLLGYAIHQQIENERMKQMLAERQFPEEYTQSLF
NITETSSNLDVNSAYTAFPVENKELFGQGLTTIVPIVGGGERLGTLVLARLGQEFLDDDLILAEYSSTVVGMEILREKAE
EIEEEARSKAVVQMAISSLSYSELEAIEHIFEELNGTEGLLVASKIADRVGITRSVIVNALRKLESAGVIESRSLGMKGT
YIKVLNDKFLHELAKLKTN

Nucleotide


Download         Length: 780 bp        

>NTDB_id=449910 FOC74_RS26560 WP_000421288.1 4738603..4739382(+) (codY) [Bacillus cereus strain FDAARGOS_780]
ATGGAATTATTAGCAAAAACAAGAAAATTAAATGCGTTATTACAGAGCGCAGCAGGAAAGCCTGTAAACTTTAGAGAAAT
GTCTGACACAATGTGTGAAGTAATCGAAGCGAACGTATTCGTAGTAAGTCGTCGTGGTAAATTACTAGGTTATGCAATTC
ACCAACAAATCGAGAATGAGCGTATGAAACAAATGCTTGCAGAACGTCAATTCCCAGAAGAGTATACACAAAGCTTATTC
AACATTACAGAAACATCTTCAAACTTAGATGTAAACAGTGCTTACACAGCATTCCCAGTAGAAAATAAAGAATTATTTGG
TCAAGGTTTAACTACAATCGTACCGATCGTTGGTGGCGGTGAGCGTCTAGGTACATTAGTTTTAGCTCGTCTTGGTCAAG
AGTTCTTAGATGATGATTTAATTCTTGCTGAGTACAGCTCAACTGTTGTAGGTATGGAAATTTTACGTGAAAAAGCAGAA
GAAATCGAAGAAGAAGCACGTAGCAAAGCTGTTGTTCAAATGGCGATCAGCTCATTATCTTACAGTGAATTAGAAGCAAT
CGAGCACATCTTCGAAGAATTAAACGGAACAGAAGGTTTACTTGTTGCAAGTAAAATTGCTGACCGCGTAGGAATCACTC
GTTCGGTAATCGTAAATGCACTTCGTAAATTAGAAAGTGCTGGTGTAATTGAGTCGCGTTCTTTAGGTATGAAAGGAACA
TACATTAAAGTATTAAACGACAAATTCTTACATGAACTTGCTAAATTAAAAACAAACTAA


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure
  AlphaFold DB Q81WK7

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  codY Bacillus subtilis subsp. subtilis str. 168

81.081

100

0.811

  codY Lactococcus lactis subsp. lactis strain DGCC12653

46.667

98.456

0.459