Detailed information NTG0449804

Bioinformatically predicted

Overview

• Name: codY
• Type: Regulator
• Locus tag: STCNRZ1202_RS07560
• Genome accession: NZ_CP065506
• Coordinates: 1446864..1447649 (-)
• Length: 261 a.a.
• NCBI ID: WP_002951720.1
• Uniprot ID: Q5M305
• Organism: Streptococcus thermophilus strain CNRZ1202
• Function: repress the expression of comX (predicted from homology) Competence regulation

Genomic Context

Location: 1441864..1452649

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
STCNRZ1202_RS07525 (STCNRZ1202_07540)	gatC	1441929..1442231 (-)	303	WP_002884769.1	Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC	-
STCNRZ1202_RS07530 (STCNRZ1202_07545)	-	1442371..1442625 (-)	255	WP_347229599.1	glycosyltransferase	-
STCNRZ1202_RS07535 (STCNRZ1202_07550)	-	1442638..1442847 (-)	210	WP_002951711.1	glycosyltransferase	-
STCNRZ1202_RS07540 (STCNRZ1202_07555)	-	1443163..1444604 (-)	1442	Protein_1430	6-phospho-beta-glucosidase	-
STCNRZ1202_RS07545 (STCNRZ1202_07560)	msrA	1444757..1445266 (-)	510	WP_002951714.1	peptide-methionine (S)-S-oxide reductase MsrA	-
STCNRZ1202_RS07550 (STCNRZ1202_07565)	-	1445278..1446126 (-)	849	WP_347229811.1	MetQ/NlpA family ABC transporter substrate-binding protein	-
STCNRZ1202_RS07555 (STCNRZ1202_07570)	-	1446250..1446801 (-)	552	WP_141326690.1	isochorismatase family cysteine hydrolase	-
STCNRZ1202_RS07560 (STCNRZ1202_07575)	codY	1446864..1447649 (-)	786	WP_002951720.1	GTP-sensing pleiotropic transcriptional regulator CodY	Regulator
STCNRZ1202_RS07565 (STCNRZ1202_07580)	-	1447909..1449123 (-)	1215	WP_180477135.1	pyridoxal phosphate-dependent aminotransferase	-
STCNRZ1202_RS07570 (STCNRZ1202_07585)	-	1449478..1449930 (+)	453	WP_180477136.1	universal stress protein	-
STCNRZ1202_RS07575 (STCNRZ1202_07590)	-	1450107..1450681 (+)	575	Protein_1437	IS30 family transposase	-
STCNRZ1202_RS07580 (STCNRZ1202_07595)	-	1450753..1450926 (-)	174	WP_347229600.1	hypothetical protein	-
STCNRZ1202_RS07585 (STCNRZ1202_07600)	-	1450987..1451361 (-)	375	WP_141326717.1	hypothetical protein	-
STCNRZ1202_RS07590 (STCNRZ1202_07605)	pflA	1451573..1452373 (-)	801	WP_002946980.1	pyruvate formate-lyase-activating protein	-

Sequence

Protein

• Length: 261 a.a.
• Molecular weight: 28919.13 Da
• Isoelectric Point: 4.5802

>NTDB_id=449804 STCNRZ1202_RS07560 WP_002951720.1 1446864..1447649(-) (codY) [Streptococcus thermophilus strain CNRZ1202]
MANLLDKTRKITSILQRSVDSLEGDLPYNNMAAQLADIIDCNAAIVNGGGALLGFAMKYKTNNDRVEKFFKAKQLPEEYI
RGISRVYDTQENIGIDSDLTIFPVELKDDFPDGLTTIAPIYGGGMRLGSFIIWRNDHDFVDDDLILVEIASTVVGLQLLH
LQTENLEETIRKQTAINMAINTLSYSEIKAVSAILNELDGLEGRLTASVIADRIGITRSVIVNALRKLESAGIIESRSLG
MKGTYLKVLNEGIYDKLKEYE

Nucleotide

• Length: 786 bp

>NTDB_id=449804 STCNRZ1202_RS07560 WP_002951720.1 1446864..1447649(-) (codY) [Streptococcus thermophilus strain CNRZ1202]
ATGGCAAATTTGCTTGATAAAACACGTAAAATTACTTCTATCTTGCAACGCTCAGTAGATAGTTTGGAAGGAGATCTTCC
ATACAACAACATGGCTGCTCAGTTGGCAGATATTATTGATTGTAATGCTGCTATTGTAAATGGTGGAGGTGCTCTCCTTG
GTTTTGCTATGAAATACAAAACCAACAATGACCGTGTGGAAAAGTTTTTTAAAGCTAAACAACTTCCAGAGGAATACATA
CGTGGTATCAGCCGTGTTTATGATACTCAAGAAAATATCGGTATTGACAGTGACTTGACCATCTTCCCAGTGGAATTAAA
AGATGATTTCCCTGACGGTTTGACTACAATTGCACCAATCTATGGTGGTGGTATGCGTCTTGGTTCTTTCATTATTTGGC
GTAACGACCATGATTTTGTGGACGACGACCTTATCTTGGTTGAGATTGCATCTACAGTAGTTGGTTTGCAATTGTTGCAT
CTTCAAACAGAAAACTTGGAAGAAACGATTCGTAAACAAACAGCTATTAATATGGCTATTAATACCTTGTCTTACTCAGA
AATCAAGGCAGTTTCAGCTATCTTGAATGAGTTGGACGGTTTAGAAGGTCGTTTGACAGCCTCTGTTATCGCGGACCGTA
TCGGAATTACTCGTTCTGTTATTGTTAATGCTCTTCGTAAATTAGAATCAGCTGGTATTATTGAAAGTCGTTCGCTTGGT
ATGAAAGGCACTTACCTTAAAGTCCTTAACGAAGGTATCTACGACAAATTGAAAGAATACGAATAA

Domains

Predicted by InterProScan.

• CodY GAF-like domain (CodY) (3-182)

• CodY helix-turn-helix domain (HTH_CodY) (201-261)

3D structure

• AlphaFold DB: Q5M305

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
codY	Lactococcus lactis subsp. lactis strain DGCC12653	64.591	98.467	0.636
codY	Bacillus subtilis subsp. subtilis str. 168	53.036	94.636	0.502