Detailed information    

insolico Bioinformatically predicted

Overview

Name   mutS/mutS2   Type   Machinery gene
Locus tag   ST4021_RS08380 Genome accession   NZ_CP065493
Coordinates   1631738..1634089 (+) Length   783 a.a.
NCBI ID   WP_011681633.1    Uniprot ID   Q03IU4
Organism   Streptococcus thermophilus strain 4021     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1626738..1639089
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ST4021_RS08355 (ST4021_08385) - 1627393..1627644 (-) 252 WP_024010075.1 hypothetical protein -
  ST4021_RS08360 (ST4021_08390) - 1627747..1627974 (-) 228 WP_011681629.1 hypothetical protein -
  ST4021_RS08365 (ST4021_08395) - 1627961..1628137 (-) 177 WP_011681630.1 hypothetical protein -
  ST4021_RS08370 (ST4021_08400) - 1628138..1628422 (-) 285 WP_011681631.1 hypothetical protein -
  ST4021_RS08375 (ST4021_08405) polA 1628892..1631531 (-) 2640 WP_011681632.1 DNA polymerase I -
  ST4021_RS08380 (ST4021_08410) mutS/mutS2 1631738..1634089 (+) 2352 WP_011681633.1 endonuclease MutS2 Machinery gene
  ST4021_RS08385 (ST4021_08415) - 1634190..1634732 (-) 543 WP_002947866.1 CvpA family protein -
  ST4021_RS08390 (ST4021_08420) - 1634729..1635046 (-) 318 WP_002947863.1 hypothetical protein -
  ST4021_RS08395 (ST4021_08425) rnhC 1635360..1636250 (+) 891 WP_011681634.1 ribonuclease HIII -
  ST4021_RS08400 (ST4021_08430) lepB 1636269..1636892 (+) 624 WP_002947854.1 signal peptidase I -

Sequence

Protein


Download         Length: 783 a.a.        Molecular weight: 88061.44 Da        Isoelectric Point: 6.6236

>NTDB_id=449082 ST4021_RS08380 WP_011681633.1 1631738..1634089(+) (mutS/mutS2) [Streptococcus thermophilus strain 4021]
MNTKILDQLEFNKVKDQFTEYLQTEQAQAELRDLVPMTNPERIQNQFTEIQEMSEIFIEHHGFAIGSLRDISEPLRRLEL
DADLNIQELIAIKKVLQASADLSRFYADLENVELIALKRLFEKIEAFPSLQGSLQSINDGGFIEHFASPELQNIRRQLKA
CDDAIRQTLQDILKKSGHMLAENLIASRNGRSVLPVKNTYRNRIAGVVHDISSSGNTVYIEPRAVIQLNEKITQLRADER
HEMARILHELSDQLRPHTAAIANNAWILGHMDFIRGKYLYLHDKKAIIPEISDNQTLQLLNVRHPLLINPVANDLRFDED
LTVIVITGPNTGGKTVMLKTLGLAQLMAQSGLPILADKGSRVAIFQEIFADIGDEQSIEQSLSTFSSHMTHIVEILNTAD
SNSLVLVDELGAGTDPQEGASLAMAILEHLRLSQIKTMATTHYPELKAYGIETQHVENASMEFDTATLRPTYRFMQGVPG
RSNAFEIARRLGLNEIIVKEAENLTDTDSDVNRIIEQLEAQTVETQKRLEHIKDVEQENLKFNRAVKKLYNEFSHEYDKE
LEKAQKEIQEMVDTALAESDSILKNLHDKSQLKPHEVIDAKGKLKKLAAQVDLSKNKVLRKAKKEKAARAPRVGDDIIVT
AYGQRGTLTSQAKNGNWEAQVGLIKMSLKADEFTLVRAQAEAQQPKKKQINVVKKAKKTSSDGPRARLDLRGKRYEEAMQ
ELDAFIDQALLNNMSQVEIIHGIGTGVIRDAVTKYLRRHRHVKNFEYAPQSAGGSGCTIATLG

Nucleotide


Download         Length: 2352 bp        

>NTDB_id=449082 ST4021_RS08380 WP_011681633.1 1631738..1634089(+) (mutS/mutS2) [Streptococcus thermophilus strain 4021]
ATGAACACAAAGATTTTAGACCAATTAGAATTTAACAAGGTCAAAGACCAGTTCACAGAATACCTGCAGACCGAACAGGC
TCAGGCGGAGTTACGTGACTTGGTGCCTATGACCAATCCAGAAAGAATTCAAAACCAATTTACAGAAATCCAAGAAATGT
CTGAGATTTTCATAGAGCATCATGGCTTTGCCATTGGTAGCTTAAGAGATATTTCTGAGCCCTTGCGTCGCTTGGAACTG
GATGCTGACCTCAACATCCAGGAGCTCATTGCTATCAAGAAGGTCTTGCAAGCTTCAGCTGACCTTAGCCGCTTCTACGC
TGACCTTGAAAATGTTGAACTCATCGCTCTTAAACGTCTTTTTGAAAAGATTGAGGCCTTTCCAAGTCTACAAGGTAGTC
TTCAAAGTATTAATGATGGTGGTTTTATTGAGCATTTTGCTAGTCCTGAGTTGCAAAATATCCGTCGTCAACTTAAGGCT
TGTGATGATGCCATTCGCCAGACCTTGCAAGACATTCTCAAGAAATCTGGGCACATGTTAGCCGAGAACTTAATTGCTAG
TCGTAATGGCCGTTCAGTGCTTCCTGTCAAAAATACCTACCGTAACCGTATTGCGGGGGTTGTTCATGACATCTCAAGCT
CTGGGAACACAGTGTATATCGAGCCACGAGCCGTTATCCAGCTTAACGAAAAAATTACACAATTACGTGCAGACGAGCGC
CATGAGATGGCACGTATCCTACATGAACTGTCTGATCAACTCCGTCCACATACTGCTGCCATCGCTAACAATGCTTGGAT
TTTGGGCCATATGGACTTCATTAGAGGAAAATACCTCTATCTCCATGATAAAAAGGCAATTATTCCAGAGATTAGTGACA
ACCAAACACTCCAACTGCTTAACGTTCGTCACCCTCTTTTAATCAATCCAGTAGCCAACGATTTGCGCTTTGATGAGGAT
CTCACGGTCATTGTCATTACAGGTCCCAATACTGGTGGTAAAACGGTCATGCTTAAAACTCTAGGACTAGCTCAACTAAT
GGCTCAATCTGGTCTGCCAATTTTGGCTGATAAGGGCAGTCGTGTAGCCATTTTCCAAGAGATTTTTGCGGATATCGGAG
ACGAACAGTCTATCGAACAGAGCTTGTCAACTTTCTCTAGTCACATGACGCACATTGTCGAGATTTTGAACACTGCCGAC
AGCAATAGCTTGGTCTTGGTCGATGAGCTTGGGGCTGGTACCGACCCTCAGGAAGGGGCTAGTCTAGCCATGGCAATCCT
AGAGCACCTCCGTTTGAGCCAGATTAAGACCATGGCTACTACTCACTATCCTGAGCTTAAGGCCTATGGGATTGAGACAC
AACATGTGGAAAATGCTAGCATGGAGTTTGACACAGCAACTCTAAGACCTACCTATCGCTTTATGCAAGGGGTTCCTGGT
CGCTCTAACGCCTTTGAGATTGCTCGCCGCCTCGGTCTGAATGAGATTATTGTCAAGGAAGCAGAAAACCTCACTGATAC
GGATAGTGATGTCAACCGTATCATCGAGCAACTTGAAGCCCAAACTGTAGAAACACAAAAACGTCTGGAGCACATCAAGG
ACGTTGAGCAAGAGAACCTTAAATTCAACCGTGCGGTCAAGAAACTCTATAATGAATTCTCCCATGAGTACGACAAGGAA
CTCGAAAAGGCTCAAAAAGAAATTCAAGAGATGGTGGATACAGCTTTAGCTGAAAGCGATAGTATTCTCAAAAATCTCCA
TGATAAGAGTCAACTCAAGCCTCATGAAGTTATCGACGCCAAAGGGAAACTTAAGAAACTTGCCGCACAAGTCGACCTTT
CTAAGAACAAGGTTCTTCGTAAAGCCAAGAAAGAAAAGGCTGCGCGTGCCCCTCGTGTCGGTGATGATATCATCGTTACT
GCCTATGGGCAACGTGGTACGCTCACCAGTCAAGCCAAAAATGGTAACTGGGAAGCTCAAGTGGGTCTCATCAAGATGAG
CCTAAAGGCAGACGAATTCACTCTGGTTCGTGCCCAAGCAGAAGCACAACAACCCAAGAAAAAACAAATTAATGTGGTTA
AAAAAGCCAAGAAGACATCTTCTGATGGGCCTCGTGCCCGTCTAGACCTTCGTGGGAAACGTTACGAAGAAGCCATGCAA
GAGCTCGATGCCTTTATTGACCAAGCTCTACTTAACAACATGAGTCAGGTGGAAATCATTCACGGTATTGGTACCGGTGT
CATCCGAGATGCTGTAACCAAATATCTCCGCCGTCATCGCCATGTTAAAAATTTTGAATATGCCCCACAAAGTGCTGGTG
GTTCCGGATGTACCATCGCAACCTTGGGTTAA

Domains

Predicted by InterProScan.

MutS domain V (MutS_V)

(324-505)

Smr domain (Smr)

(708-782)

MutS2 and Smr-associated SH3 domain (MSSS)

(633-672)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q03IU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mutS/mutS2 Bacillus subtilis subsp. subtilis str. 168

39.295

100

0.398