Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGE   Type   Machinery gene
Locus tag   STAVA1121_RS08905 Genome accession   NZ_CP065488
Coordinates   1691643..1691936 (-) Length   97 a.a.
NCBI ID   WP_011226625.1    Uniprot ID   Q5M2G2
Organism   Streptococcus thermophilus strain AVA1121     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1686643..1696936
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  STAVA1121_RS08870 (STAVA1121_08750) - 1687047..1687490 (-) 444 WP_347131253.1 CAAX protease -
  STAVA1121_RS08875 - 1687564..1687902 (-) 339 WP_347131255.1 CPBP family intramembrane glutamic endopeptidase -
  STAVA1121_RS08880 (STAVA1121_08760) - 1688232..1688429 (-) 198 WP_002885716.1 helix-turn-helix transcriptional regulator -
  STAVA1121_RS08885 (STAVA1121_08765) - 1688677..1689870 (-) 1194 WP_347131256.1 acetate kinase -
  STAVA1121_RS08890 (STAVA1121_08770) comGH 1689926..1690882 (-) 957 WP_011226622.1 class I SAM-dependent methyltransferase Machinery gene
  STAVA1121_RS08895 (STAVA1121_08775) comGG 1690927..1691244 (-) 318 WP_002952035.1 competence type IV pilus minor pilin ComGG Machinery gene
  STAVA1121_RS08900 (STAVA1121_08780) comGF 1691222..1691659 (-) 438 WP_082309153.1 competence type IV pilus minor pilin ComGF Machinery gene
  STAVA1121_RS08905 (STAVA1121_08785) comGE 1691643..1691936 (-) 294 WP_011226625.1 competence type IV pilus minor pilin ComGE Machinery gene
  STAVA1121_RS08910 (STAVA1121_08790) comGD 1691908..1692336 (-) 429 WP_011226626.1 competence type IV pilus minor pilin ComGD Machinery gene
  STAVA1121_RS08915 (STAVA1121_08795) comGC 1692296..1692622 (-) 327 WP_002946126.1 competence type IV pilus major pilin ComGC Machinery gene
  STAVA1121_RS08920 (STAVA1121_08800) comGB 1692619..1693718 (-) 1100 Protein_1699 competence type IV pilus assembly protein ComGB -
  STAVA1121_RS08925 (STAVA1121_08805) comGA/cglA/cilD 1693600..1694541 (-) 942 WP_022096896.1 competence type IV pilus ATPase ComGA Machinery gene
  STAVA1121_RS08930 (STAVA1121_08810) - 1694622..1694984 (-) 363 WP_011226630.1 DUF1033 family protein -

Sequence

Protein


Download         Length: 97 a.a.        Molecular weight: 10844.74 Da        Isoelectric Point: 10.4561

>NTDB_id=448577 STAVA1121_RS08905 WP_011226625.1 1691643..1691936(-) (comGE) [Streptococcus thermophilus strain AVA1121]
MVNIKRRSLRGYILIESLVAMAVLVLVSSLILEQINTNRRLMADNLHQQEVLSVATMAVQTKQDQLTLNGIAVTVKRSQQ
GITVYESGKEIIHVSKQ

Nucleotide


Download         Length: 294 bp        

>NTDB_id=448577 STAVA1121_RS08905 WP_011226625.1 1691643..1691936(-) (comGE) [Streptococcus thermophilus strain AVA1121]
GTGGTAAATATAAAAAGACGATCTCTTAGAGGTTATATTCTTATTGAAAGTCTGGTAGCTATGGCTGTTTTAGTACTTGT
CAGCAGTCTGATATTGGAACAAATTAATACCAACCGCAGACTAATGGCTGATAATCTCCATCAACAAGAGGTCTTGAGTG
TGGCAACAATGGCAGTTCAGACCAAGCAAGACCAGTTAACGCTGAATGGCATAGCGGTGACAGTTAAACGTAGCCAGCAA
GGTATCACGGTTTATGAATCGGGAAAGGAGATTATTCATGTATCTAAGCAGTAA

Domains

Predicted by InterProScan.

Type II secretory pathway pseudopilin (ComGE)

(13-94)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q5M2G2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE Streptococcus mutans UA140

43.299

100

0.433
  comGE Streptococcus mutans UA159

43.299

100

0.433
  comGE Lactococcus lactis subsp. cremoris KW2

36.082

100

0.361