Detailed information
Bioinformatically predicted
Overview
| Name | comYH | Type | Machinery gene |
| Locus tag | HQ611_RS01135 | Genome accession | NZ_CP053887 |
| Coordinates | 190740..191714 (+) | Length | 324 a.a. |
| NCBI ID | WP_001008574.1 | Uniprot ID | A0AAV3JGK6 |
| Organism | Streptococcus agalactiae strain SS102 | ||
| Function | dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| ICE | 190955..241512 | 190740..191714 | flank | -759 |
Gene organization within MGE regions
Location: 190740..241512
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| HQ611_RS01135 (HQ611_01135) | comYH | 190740..191714 (+) | 975 | WP_001008574.1 | class I SAM-dependent methyltransferase | Machinery gene |
| HQ611_RS01140 (HQ611_01140) | - | 191746..192939 (+) | 1194 | WP_000047534.1 | acetate kinase | - |
| HQ611_RS01145 (HQ611_01145) | - | 193091..193297 (+) | 207 | WP_000798241.1 | helix-turn-helix transcriptional regulator | - |
| HQ611_RS01150 (HQ611_01150) | - | 193356..193493 (+) | 138 | WP_001865900.1 | hypothetical protein | - |
| HQ611_RS01155 (HQ611_01155) | - | 193534..193989 (+) | 456 | WP_000905673.1 | hypothetical protein | - |
| HQ611_RS01160 (HQ611_01160) | - | 194058..194723 (+) | 666 | WP_000008113.1 | CPBP family intramembrane glutamic endopeptidase | - |
| HQ611_RS01165 (HQ611_01165) | proC | 194744..195514 (-) | 771 | WP_001865901.1 | pyrroline-5-carboxylate reductase | - |
| HQ611_RS01170 (HQ611_01170) | pepA | 195584..196651 (-) | 1068 | WP_001281323.1 | glutamyl aminopeptidase | - |
| HQ611_RS01175 (HQ611_01175) | - | 196836..197075 (-) | 240 | WP_000660180.1 | hypothetical protein | - |
| HQ611_RS01180 (HQ611_01180) | - | 197235..197519 (+) | 285 | WP_000791272.1 | DUF4651 domain-containing protein | - |
| HQ611_RS01185 (HQ611_01185) | - | 197516..197839 (+) | 324 | WP_000602781.1 | thioredoxin family protein | - |
| HQ611_RS01190 (HQ611_01190) | ytpR | 197872..198498 (+) | 627 | WP_000578328.1 | YtpR family tRNA-binding protein | - |
| HQ611_RS01195 (HQ611_01195) | - | 198552..199268 (-) | 717 | WP_000186185.1 | class I SAM-dependent methyltransferase | - |
| HQ611_RS01200 (HQ611_01200) | ssbA | 199349..199744 (+) | 396 | WP_000282447.1 | single-stranded DNA-binding protein | Machinery gene |
| HQ611_RS01205 (HQ611_01205) | - | 199868..200512 (+) | 645 | WP_000416612.1 | HAD family phosphatase | - |
| HQ611_RS01210 (HQ611_01210) | - | 200539..202284 (+) | 1746 | WP_000930334.1 | LytS/YhcK type 5TM receptor domain-containing protein | - |
| HQ611_RS01215 (HQ611_01215) | - | 202265..203005 (+) | 741 | WP_000697630.1 | LytTR family DNA-binding domain-containing protein | - |
| HQ611_RS01220 (HQ611_01220) | - | 203175..203630 (+) | 456 | WP_000683316.1 | CidA/LrgA family protein | - |
| HQ611_RS01225 (HQ611_01225) | lrgB | 203632..204360 (+) | 729 | WP_000421726.1 | antiholin-like protein LrgB | - |
| HQ611_RS01230 (HQ611_01230) | - | 204603..206231 (+) | 1629 | WP_000170504.1 | ABC transporter substrate-binding protein | - |
| HQ611_RS01235 (HQ611_01235) | - | 206344..207321 (+) | 978 | WP_000680645.1 | ABC transporter permease | - |
| HQ611_RS01240 (HQ611_01240) | - | 207318..208139 (+) | 822 | WP_000603397.1 | ABC transporter permease | - |
| HQ611_RS01245 (HQ611_01245) | - | 208151..208954 (+) | 804 | WP_000140984.1 | ABC transporter ATP-binding protein | - |
| HQ611_RS01250 (HQ611_01250) | - | 208938..209564 (+) | 627 | WP_000171311.1 | ABC transporter ATP-binding protein | - |
| HQ611_RS01255 (HQ611_01255) | treP | 209847..211877 (+) | 2031 | WP_000434616.1 | PTS system trehalose-specific EIIBC component | - |
| HQ611_RS01260 (HQ611_01260) | treC | 212099..213724 (+) | 1626 | WP_000151017.1 | alpha,alpha-phosphotrehalase | - |
| HQ611_RS01265 (HQ611_01265) | - | 213940..215976 (+) | 2037 | WP_000228180.1 | BglG family transcription antiterminator | - |
| HQ611_RS01270 (HQ611_01270) | - | 215979..216263 (+) | 285 | WP_000944235.1 | PTS sugar transporter subunit IIB | - |
| HQ611_RS01275 (HQ611_01275) | - | 216276..217631 (+) | 1356 | WP_000677351.1 | PTS ascorbate transporter subunit IIC | - |
| HQ611_RS01280 (HQ611_01280) | - | 217634..218491 (+) | 858 | WP_000203489.1 | transketolase | - |
| HQ611_RS01285 (HQ611_01285) | - | 218488..219417 (+) | 930 | WP_001203821.1 | transketolase family protein | - |
| HQ611_RS01290 (HQ611_01290) | - | 219526..220785 (+) | 1260 | WP_001203071.1 | ferric reductase-like transmembrane domain-containing protein | - |
| HQ611_RS01295 (HQ611_01295) | rpsO | 220873..221142 (+) | 270 | WP_001018249.1 | 30S ribosomal protein S15 | - |
| HQ611_RS01300 (HQ611_01300) | pnp | 221523..223652 (+) | 2130 | WP_000043850.1 | polyribonucleotide nucleotidyltransferase | - |
| HQ611_RS01305 (HQ611_01305) | - | 223654..224406 (+) | 753 | WP_000204782.1 | SseB family protein | - |
| HQ611_RS01310 (HQ611_01310) | cysE | 224415..224999 (+) | 585 | WP_000539954.1 | serine O-acetyltransferase | - |
| HQ611_RS01315 (HQ611_01315) | - | 225009..225191 (+) | 183 | WP_000656476.1 | lipoprotein | - |
| HQ611_RS01320 (HQ611_01320) | cysS | 225188..226531 (+) | 1344 | WP_000591125.1 | cysteine--tRNA ligase | - |
| HQ611_RS01325 (HQ611_01325) | - | 226524..226910 (+) | 387 | WP_000568029.1 | Mini-ribonuclease 3 | - |
| HQ611_RS01330 (HQ611_01330) | rlmB | 227013..227768 (+) | 756 | WP_000178026.1 | 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB | - |
| HQ611_RS01335 (HQ611_01335) | - | 227765..228283 (+) | 519 | WP_000716636.1 | NYN domain-containing protein | - |
| HQ611_RS01340 (HQ611_01340) | - | 228376..229236 (+) | 861 | WP_000143135.1 | DegV family protein | - |
| HQ611_RS01345 | - | 229773..229892 (+) | 120 | Protein_209 | helix-turn-helix transcriptional regulator | - |
| HQ611_RS01350 (HQ611_01345) | rplM | 230117..230563 (+) | 447 | WP_001865567.1 | 50S ribosomal protein L13 | - |
| HQ611_RS01355 (HQ611_01350) | rpsI | 230584..230976 (+) | 393 | WP_000035940.1 | 30S ribosomal protein S9 | - |
| HQ611_RS01360 (HQ611_01355) | - | 231104..232258 (-) | 1155 | WP_000022165.1 | site-specific integrase | - |
| HQ611_RS01365 (HQ611_01360) | - | 232322..232912 (-) | 591 | WP_000181098.1 | helix-turn-helix domain-containing protein | - |
| HQ611_RS01370 (HQ611_01365) | - | 233067..233372 (+) | 306 | WP_000331954.1 | hypothetical protein | - |
| HQ611_RS01375 (HQ611_01370) | - | 233508..233786 (+) | 279 | WP_000134670.1 | hypothetical protein | - |
| HQ611_RS01380 (HQ611_01375) | - | 233797..234027 (+) | 231 | WP_000360142.1 | hypothetical protein | - |
| HQ611_RS01385 (HQ611_01380) | - | 234040..234366 (+) | 327 | WP_000384270.1 | replication initiator protein A | - |
| HQ611_RS01390 (HQ611_01385) | - | 234370..234999 (+) | 630 | WP_000591148.1 | hypothetical protein | - |
| HQ611_RS01395 (HQ611_01390) | - | 235312..236187 (+) | 876 | WP_000770113.1 | hypothetical protein | - |
| HQ611_RS01400 (HQ611_01395) | - | 236223..236657 (+) | 435 | WP_001220479.1 | hypothetical protein | - |
| HQ611_RS01405 (HQ611_01400) | mobV | 236973..238229 (+) | 1257 | WP_000122832.1 | MobV family relaxase | - |
| HQ611_RS01410 (HQ611_01405) | - | 238397..238867 (+) | 471 | WP_000130119.1 | hypothetical protein | - |
| HQ611_RS01415 (HQ611_01410) | - | 239172..239507 (-) | 336 | WP_000384858.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| HQ611_RS01420 (HQ611_01415) | - | 239497..239784 (-) | 288 | WP_000255538.1 | hypothetical protein | - |
| HQ611_RS01425 (HQ611_01420) | - | 240187..241407 (-) | 1221 | WP_000156558.1 | site-specific integrase | - |
Sequence
Protein
Download Length: 324 a.a. Molecular weight: 37046.02 Da Isoelectric Point: 4.5224
>NTDB_id=448520 HQ611_RS01135 WP_001008574.1 190740..191714(+) (comYH) [Streptococcus agalactiae strain SS102]
MNFEKIETAYELILENIQTIENQLKTHIYDALIEQNSYYLGSSCDLDMVVVNNQKLRQLDLSQEEWRRTFQFIFIKSAQT
EQLQANHQFTPDSIGFILLFLLEELTSQETVDVLEIGSGTGNLAQTLLNNSSKELNYMGIEVDDLLIDLSASIAEIIGSS
AQFIQEDAVRPQILKESDVIISDLPVGYYPNDGIAKRYAVSSSKEHTYAHHLLMEQSLKYLKKDGIAIFLAPENLLTSPQ
SDLLKEWLKGYADVIAVLTLPETIFGSRQNAKSIFVLKKQAEQKPETFVYPLTDLQNRENMANFIENFQKWSRENSHYSK
NMIK
MNFEKIETAYELILENIQTIENQLKTHIYDALIEQNSYYLGSSCDLDMVVVNNQKLRQLDLSQEEWRRTFQFIFIKSAQT
EQLQANHQFTPDSIGFILLFLLEELTSQETVDVLEIGSGTGNLAQTLLNNSSKELNYMGIEVDDLLIDLSASIAEIIGSS
AQFIQEDAVRPQILKESDVIISDLPVGYYPNDGIAKRYAVSSSKEHTYAHHLLMEQSLKYLKKDGIAIFLAPENLLTSPQ
SDLLKEWLKGYADVIAVLTLPETIFGSRQNAKSIFVLKKQAEQKPETFVYPLTDLQNRENMANFIENFQKWSRENSHYSK
NMIK
Nucleotide
Download Length: 975 bp
>NTDB_id=448520 HQ611_RS01135 WP_001008574.1 190740..191714(+) (comYH) [Streptococcus agalactiae strain SS102]
ATGAATTTTGAAAAAATTGAGACAGCCTATGAGCTGATTTTAGAAAATATCCAAACGATTGAGAACCAATTAAAAACTCA
TATTTATGATGCCTTAATTGAACAGAACTCTTATTACCTTGGTTCAAGTTGTGATTTAGATATGGTTGTGGTGAATAACC
AAAAATTACGTCAACTTGACTTAAGTCAAGAAGAATGGCGTCGCACTTTCCAGTTCATTTTTATCAAATCTGCGCAAACA
GAGCAATTACAAGCTAATCATCAGTTTACGCCAGATAGTATTGGTTTTATCTTGTTATTTCTTTTGGAAGAATTAACGAG
TCAAGAGACAGTGGATGTCTTGGAAATTGGAAGTGGAACTGGGAATTTAGCTCAGACTCTCCTCAATAACAGCTCGAAAG
AGTTAAATTATATGGGCATTGAAGTTGATGATCTTTTGATTGATCTATCAGCAAGCATTGCTGAAATTATAGGTTCTAGT
GCCCAATTTATCCAAGAGGATGCTGTTAGACCACAAATTTTGAAAGAAAGCGATGTAATCATTAGTGATTTACCAGTTGG
CTATTATCCTAATGATGGTATTGCTAAACGATATGCTGTATCAAGTTCTAAAGAGCACACCTATGCTCACCATCTATTGA
TGGAGCAATCTCTTAAATATTTGAAAAAAGATGGAATCGCTATATTTTTAGCACCCGAAAACCTTTTAACAAGTCCACAA
AGTGATTTGCTGAAGGAGTGGTTAAAAGGATATGCAGATGTCATTGCCGTTTTAACTCTACCAGAAACTATTTTTGGAAG
TCGTCAAAATGCGAAATCTATATTTGTTCTCAAGAAGCAAGCAGAACAAAAACCAGAAACCTTTGTATATCCGCTGACAG
ATTTGCAAAATCGTGAGAATATGGCAAACTTCATTGAAAATTTTCAAAAATGGAGCAGAGAAAATAGTCATTACTCAAAA
AATATGATAAAATAG
ATGAATTTTGAAAAAATTGAGACAGCCTATGAGCTGATTTTAGAAAATATCCAAACGATTGAGAACCAATTAAAAACTCA
TATTTATGATGCCTTAATTGAACAGAACTCTTATTACCTTGGTTCAAGTTGTGATTTAGATATGGTTGTGGTGAATAACC
AAAAATTACGTCAACTTGACTTAAGTCAAGAAGAATGGCGTCGCACTTTCCAGTTCATTTTTATCAAATCTGCGCAAACA
GAGCAATTACAAGCTAATCATCAGTTTACGCCAGATAGTATTGGTTTTATCTTGTTATTTCTTTTGGAAGAATTAACGAG
TCAAGAGACAGTGGATGTCTTGGAAATTGGAAGTGGAACTGGGAATTTAGCTCAGACTCTCCTCAATAACAGCTCGAAAG
AGTTAAATTATATGGGCATTGAAGTTGATGATCTTTTGATTGATCTATCAGCAAGCATTGCTGAAATTATAGGTTCTAGT
GCCCAATTTATCCAAGAGGATGCTGTTAGACCACAAATTTTGAAAGAAAGCGATGTAATCATTAGTGATTTACCAGTTGG
CTATTATCCTAATGATGGTATTGCTAAACGATATGCTGTATCAAGTTCTAAAGAGCACACCTATGCTCACCATCTATTGA
TGGAGCAATCTCTTAAATATTTGAAAAAAGATGGAATCGCTATATTTTTAGCACCCGAAAACCTTTTAACAAGTCCACAA
AGTGATTTGCTGAAGGAGTGGTTAAAAGGATATGCAGATGTCATTGCCGTTTTAACTCTACCAGAAACTATTTTTGGAAG
TCGTCAAAATGCGAAATCTATATTTGTTCTCAAGAAGCAAGCAGAACAAAAACCAGAAACCTTTGTATATCCGCTGACAG
ATTTGCAAAATCGTGAGAATATGGCAAACTTCATTGAAAATTTTCAAAAATGGAGCAGAGAAAATAGTCATTACTCAAAA
AATATGATAAAATAG
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| comYH | Streptococcus mutans UA159 |
67.302 |
97.222 |
0.654 |
| comYH | Streptococcus mutans UA140 |
67.302 |
97.222 |
0.654 |