Detailed information NTG0448033

Bioinformatically predicted

Overview

• Name: codY
• Type: Regulator
• Locus tag: STCNRZ1151_RS07635
• Genome accession: NZ_CP065483
• Coordinates: 1451977..1452762 (-)
• Length: 261 a.a.
• NCBI ID: WP_002951720.1
• Uniprot ID: Q5M305
• Organism: Streptococcus thermophilus strain CNRZ1151
• Function: repress the expression of comX (predicted from homology) Competence regulation

Genomic Context

Location: 1446977..1457762

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
STCNRZ1151_RS07600 (STCNRZ1151_07590)	gatC	1447043..1447345 (-)	303	WP_002884769.1	Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC	-
STCNRZ1151_RS07605 (STCNRZ1151_07595)	-	1447485..1447739 (-)	255	WP_011226449.1	glycosyl transferase	-
STCNRZ1151_RS07610 (STCNRZ1151_07600)	-	1447752..1447961 (-)	210	WP_011226450.1	glycosyltransferase	-
STCNRZ1151_RS07615 (STCNRZ1151_07605)	-	1448277..1449718 (-)	1442	Protein_1436	6-phospho-beta-glucosidase	-
STCNRZ1151_RS07620 (STCNRZ1151_07610)	msrA	1449871..1450380 (-)	510	WP_002946589.1	peptide-methionine (S)-S-oxide reductase MsrA	-
STCNRZ1151_RS07625 (STCNRZ1151_07615)	-	1450392..1451240 (-)	849	WP_041828318.1	MetQ/NlpA family ABC transporter substrate-binding protein	-
STCNRZ1151_RS07630 (STCNRZ1151_07620)	-	1451363..1451914 (-)	552	WP_002946999.1	cysteine hydrolase family protein	-
STCNRZ1151_RS07635 (STCNRZ1151_07625)	codY	1451977..1452762 (-)	786	WP_002951720.1	GTP-sensing pleiotropic transcriptional regulator CodY	Regulator
STCNRZ1151_RS07640 (STCNRZ1151_07630)	-	1453022..1454236 (-)	1215	WP_011226456.1	pyridoxal phosphate-dependent aminotransferase	-
STCNRZ1151_RS07645 (STCNRZ1151_07635)	-	1454591..1455043 (+)	453	WP_002946987.1	universal stress protein	-
STCNRZ1151_RS07650	-	1455223..1455794 (+)	572	Protein_1443	IS30 family transposase	-
STCNRZ1151_RS07655 (STCNRZ1151_07640)	-	1456010..1456480 (-)	471	WP_011227497.1	membrane protein	-
STCNRZ1151_RS07660 (STCNRZ1151_07645)	pflA	1456686..1457486 (-)	801	WP_002946980.1	pyruvate formate-lyase-activating protein	-

Sequence

Protein

• Length: 261 a.a.
• Molecular weight: 28919.13 Da
• Isoelectric Point: 4.5802

>NTDB_id=448033 STCNRZ1151_RS07635 WP_002951720.1 1451977..1452762(-) (codY) [Streptococcus thermophilus strain CNRZ1151]
MANLLDKTRKITSILQRSVDSLEGDLPYNNMAAQLADIIDCNAAIVNGGGALLGFAMKYKTNNDRVEKFFKAKQLPEEYI
RGISRVYDTQENIGIDSDLTIFPVELKDDFPDGLTTIAPIYGGGMRLGSFIIWRNDHDFVDDDLILVEIASTVVGLQLLH
LQTENLEETIRKQTAINMAINTLSYSEIKAVSAILNELDGLEGRLTASVIADRIGITRSVIVNALRKLESAGIIESRSLG
MKGTYLKVLNEGIYDKLKEYE

Nucleotide

• Length: 786 bp

>NTDB_id=448033 STCNRZ1151_RS07635 WP_002951720.1 1451977..1452762(-) (codY) [Streptococcus thermophilus strain CNRZ1151]
ATGGCAAATTTGCTTGATAAAACACGTAAAATTACTTCTATCTTGCAACGCTCAGTAGATAGTTTGGAAGGAGATCTTCC
ATACAACAACATGGCTGCTCAGTTGGCAGATATTATTGATTGTAATGCTGCTATTGTAAATGGTGGAGGTGCTCTCCTTG
GTTTTGCTATGAAATACAAAACCAACAATGACCGTGTGGAAAAGTTTTTTAAAGCTAAACAACTTCCAGAGGAATACATA
CGTGGTATCAGCCGTGTTTATGATACTCAAGAAAATATCGGTATTGACAGTGACTTGACCATCTTCCCAGTAGAATTAAA
AGATGATTTCCCTGACGGTTTGACTACAATTGCACCAATCTATGGTGGTGGTATGCGTCTTGGTTCTTTCATTATTTGGC
GTAACGACCATGATTTTGTGGACGACGACCTTATCTTGGTTGAGATTGCATCTACAGTAGTTGGTTTGCAATTGTTGCAT
CTTCAAACAGAAAACTTGGAAGAAACGATTCGTAAACAAACAGCTATTAATATGGCTATTAATACCTTATCTTACTCAGA
AATCAAGGCAGTTTCAGCTATCTTGAATGAGTTGGACGGTTTAGAAGGTCGTTTGACAGCCTCTGTTATCGCGGACCGTA
TCGGAATTACTCGTTCTGTTATTGTTAATGCTCTTCGTAAATTAGAATCAGCTGGTATTATTGAAAGTCGTTCGCTTGGT
ATGAAAGGTACTTACCTTAAAGTCCTTAACGAAGGTATCTACGACAAATTGAAAGAATACGAATAA

Domains

Predicted by InterProScan.

• CodY GAF-like domain (CodY) (3-182)

• CodY helix-turn-helix domain (HTH_CodY) (201-261)

3D structure

• AlphaFold DB: Q5M305

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
codY	Lactococcus lactis subsp. lactis strain DGCC12653	64.591	98.467	0.636
codY	Bacillus subtilis subsp. subtilis str. 168	53.036	94.636	0.502