Detailed information NTG0447936

Bioinformatically predicted

Overview

• Name: codY
• Type: Regulator
• Locus tag: STCNRZ760_RS07995
• Genome accession: NZ_CP065482
• Coordinates: 1526345..1527130 (-)
• Length: 261 a.a.
• NCBI ID: WP_002951720.1
• Uniprot ID: Q5M305
• Organism: Streptococcus thermophilus strain CNRZ760
• Function: repress the expression of comX (predicted from homology) Competence regulation

Genomic Context

Location: 1521345..1532130

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
STCNRZ760_RS07960 (STCNRZ760_07890)	gatC	1521412..1521714 (-)	303	WP_002884769.1	Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC	-
STCNRZ760_RS07965 (STCNRZ760_07895)	-	1521854..1522108 (-)	255	WP_180481089.1	glycosyltransferase	-
STCNRZ760_RS07970 (STCNRZ760_07900)	-	1522121..1522330 (-)	210	WP_180481090.1	glycosyltransferase	-
STCNRZ760_RS07975 (STCNRZ760_07905)	-	1522646..1524086 (-)	1441	Protein_1518	6-phospho-beta-glucosidase	-
STCNRZ760_RS07980 (STCNRZ760_07910)	msrA	1524239..1524748 (-)	510	WP_002951714.1	peptide-methionine (S)-S-oxide reductase MsrA	-
STCNRZ760_RS07985 (STCNRZ760_07915)	-	1524760..1525608 (-)	849	WP_041828318.1	MetQ/NlpA family ABC transporter substrate-binding protein	-
STCNRZ760_RS07990 (STCNRZ760_07920)	-	1525731..1526282 (-)	552	WP_002946999.1	isochorismatase family cysteine hydrolase	-
STCNRZ760_RS07995 (STCNRZ760_07925)	codY	1526345..1527130 (-)	786	WP_002951720.1	GTP-sensing pleiotropic transcriptional regulator CodY	Regulator
STCNRZ760_RS08000 (STCNRZ760_07930)	-	1527390..1528604 (-)	1215	WP_224103607.1	pyridoxal phosphate-dependent aminotransferase	-
STCNRZ760_RS08005 (STCNRZ760_07935)	-	1528959..1529411 (+)	453	WP_002946987.1	universal stress protein	-
STCNRZ760_RS08010 (STCNRZ760_07940)	-	1529591..1530162 (+)	572	Protein_1525	IS30 family transposase	-
STCNRZ760_RS08015	-	1530234..1530842 (-)	609	WP_002946982.1	hypothetical protein	-
STCNRZ760_RS08020 (STCNRZ760_07950)	pflA	1531054..1531854 (-)	801	WP_002946980.1	pyruvate formate-lyase-activating protein	-

Sequence

Protein

• Length: 261 a.a.
• Molecular weight: 28919.13 Da
• Isoelectric Point: 4.5802

>NTDB_id=447936 STCNRZ760_RS07995 WP_002951720.1 1526345..1527130(-) (codY) [Streptococcus thermophilus strain CNRZ760]
MANLLDKTRKITSILQRSVDSLEGDLPYNNMAAQLADIIDCNAAIVNGGGALLGFAMKYKTNNDRVEKFFKAKQLPEEYI
RGISRVYDTQENIGIDSDLTIFPVELKDDFPDGLTTIAPIYGGGMRLGSFIIWRNDHDFVDDDLILVEIASTVVGLQLLH
LQTENLEETIRKQTAINMAINTLSYSEIKAVSAILNELDGLEGRLTASVIADRIGITRSVIVNALRKLESAGIIESRSLG
MKGTYLKVLNEGIYDKLKEYE

Nucleotide

• Length: 786 bp

>NTDB_id=447936 STCNRZ760_RS07995 WP_002951720.1 1526345..1527130(-) (codY) [Streptococcus thermophilus strain CNRZ760]
ATGGCAAATTTGCTTGATAAAACACGTAAAATTACTTCTATCTTGCAACGCTCAGTAGATAGTTTGGAAGGAGATCTTCC
ATACAACAACATGGCTGCTCAGTTGGCAGATATTATTGATTGTAATGCTGCTATTGTAAATGGTGGAGGTGCTCTCCTTG
GTTTTGCTATGAAATACAAAACCAACAATGACCGTGTGGAAAAGTTTTTTAAAGCTAAACAACTTCCAGAGGAATACATA
CGTGGTATCAGCCGTGTTTATGATACTCAAGAAAATATCGGTATTGACAGTGACTTGACCATCTTCCCAGTGGAATTAAA
AGATGATTTCCCTGACGGTTTGACTACAATTGCACCAATCTATGGTGGTGGTATGCGTCTTGGTTCTTTCATTATTTGGC
GTAACGACCATGATTTTGTGGACGACGACCTTATCTTGGTTGAGATTGCATCTACAGTAGTTGGTTTGCAATTGTTGCAT
CTTCAAACAGAAAACTTGGAAGAAACGATTCGTAAACAAACAGCTATTAATATGGCTATTAATACCTTGTCTTACTCAGA
AATCAAGGCAGTTTCAGCTATCTTGAATGAGTTGGACGGTTTAGAAGGTCGTTTGACAGCCTCTGTTATCGCGGACCGTA
TCGGAATTACTCGTTCTGTTATTGTTAATGCTCTTCGTAAATTAGAATCAGCTGGTATTATTGAAAGTCGTTCGCTTGGT
ATGAAAGGTACTTACCTTAAAGTCCTTAACGAAGGTATCTACGACAAATTGAAAGAATACGAATAA

Domains

Predicted by InterProScan.

• CodY GAF-like domain (CodY) (3-182)

• CodY helix-turn-helix domain (HTH_CodY) (201-261)

3D structure

• AlphaFold DB: Q5M305

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
codY	Lactococcus lactis subsp. lactis strain DGCC12653	64.591	98.467	0.636
codY	Bacillus subtilis subsp. subtilis str. 168	53.036	94.636	0.502