Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGE   Type   Machinery gene
Locus tag   ST4052_RS08480 Genome accession   NZ_CP065476
Coordinates   1632256..1632549 (-) Length   97 a.a.
NCBI ID   WP_347100874.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain 4052     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1627256..1637549
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ST4052_RS08445 (ST4052_08510) - 1627654..1628102 (-) 449 Protein_1605 CAAX protease -
  ST4052_RS08450 - 1628176..1628601 (-) 426 WP_041827107.1 CPBP family intramembrane glutamic endopeptidase -
  ST4052_RS08455 (ST4052_08520) - 1628844..1629041 (-) 198 WP_011681682.1 helix-turn-helix transcriptional regulator -
  ST4052_RS08460 (ST4052_08525) - 1629290..1630483 (-) 1194 WP_022096898.1 acetate kinase -
  ST4052_RS08465 (ST4052_08530) comGH 1630539..1631495 (-) 957 WP_011226622.1 class I SAM-dependent methyltransferase Machinery gene
  ST4052_RS08470 (ST4052_08535) comGG 1631540..1631857 (-) 318 WP_002952035.1 competence type IV pilus minor pilin ComGG Machinery gene
  ST4052_RS08475 (ST4052_08540) comGF 1631835..1632272 (-) 438 WP_014608742.1 competence type IV pilus minor pilin ComGF Machinery gene
  ST4052_RS08480 (ST4052_08545) comGE 1632256..1632549 (-) 294 WP_347100874.1 competence type IV pilus minor pilin ComGE Machinery gene
  ST4052_RS08485 (ST4052_08550) comGD 1632521..1632949 (-) 429 WP_011226626.1 competence type IV pilus minor pilin ComGD Machinery gene
  ST4052_RS08490 (ST4052_08555) comGC 1632909..1633235 (-) 327 WP_002946126.1 competence type IV pilus major pilin ComGC Machinery gene
  ST4052_RS08495 (ST4052_08560) comGB 1633232..1634332 (-) 1101 WP_148148900.1 competence type IV pilus assembly protein ComGB Machinery gene
  ST4052_RS08500 (ST4052_08565) comGA/cglA/cilD 1634214..1635155 (-) 942 WP_011226629.1 competence type IV pilus ATPase ComGA Machinery gene
  ST4052_RS08505 (ST4052_08570) - 1635236..1635598 (-) 363 WP_011226630.1 DUF1033 family protein -

Sequence

Protein


Download         Length: 97 a.a.        Molecular weight: 10853.75 Da        Isoelectric Point: 10.4561

>NTDB_id=447322 ST4052_RS08480 WP_347100874.1 1632256..1632549(-) (comGE) [Streptococcus thermophilus strain 4052]
MVNIKRRSLRGYILIESLVAMAVLVLVSSLILEQINTNRRLMADNLHQQEVLSVATMAVQTKQDQLTLNGIAVTVKRSHQ
GITVYESGKEIIHVSKQ

Nucleotide


Download         Length: 294 bp        

>NTDB_id=447322 ST4052_RS08480 WP_347100874.1 1632256..1632549(-) (comGE) [Streptococcus thermophilus strain 4052]
GTGGTAAATATAAAAAGACGATCTCTTAGAGGTTATATTCTTATTGAAAGTCTGGTAGCTATGGCTGTTTTAGTACTTGT
CAGCAGTCTGATATTGGAACAAATTAATACCAACCGCAGACTAATGGCTGATAATCTCCATCAACAAGAGGTCTTGAGTG
TGGCAACAATGGCAGTTCAGACCAAGCAAGACCAGTTAACGCTGAATGGCATAGCGGTGACAGTTAAACGTAGCCATCAA
GGTATCACGGTTTATGAATCGGGAAAGGAGATTATTCATGTATCTAAGCAGTAA

Domains

Predicted by InterProScan.

Type II secretory pathway pseudopilin (ComGE)

(13-94)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE Streptococcus mutans UA140

42.268

100

0.423
  comGE Streptococcus mutans UA159

42.268

100

0.423
  comGE Lactococcus lactis subsp. cremoris KW2

36.082

100

0.361