Detailed information    

insolico Bioinformatically predicted

Overview

Name   endA   Type   Machinery gene
Locus tag   GE021_RS03785 Genome accession   NZ_CP053792
Coordinates   757403..758269 (+) Length   288 a.a.
NCBI ID   WP_125073792.1    Uniprot ID   A0A3P5XMH9
Organism   Streptococcus canis strain HL_77_1     
Function   cleavage of dsDNA into ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 752403..763269
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GE021_RS03755 (GE021_003755) - 752427..753302 (+) 876 WP_164407633.1 F0F1 ATP synthase subunit gamma -
  GE021_RS03760 (GE021_003760) atpD 753464..754870 (+) 1407 WP_093998505.1 F0F1 ATP synthase subunit beta -
  GE021_RS03765 (GE021_003765) - 754883..755299 (+) 417 WP_003050138.1 F0F1 ATP synthase subunit epsilon -
  GE021_RS03770 (GE021_003770) - 755600..755836 (+) 237 WP_282917434.1 DUF1146 family protein -
  GE021_RS03775 (GE021_003775) murA 755901..757175 (+) 1275 WP_099983021.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  GE021_RS03780 (GE021_003780) - 757179..757367 (+) 189 WP_125073793.1 DNA-directed RNA polymerase subunit beta -
  GE021_RS03785 (GE021_003785) endA 757403..758269 (+) 867 WP_125073792.1 DNA/RNA non-specific endonuclease Machinery gene
  GE021_RS03790 (GE021_003790) pheS 758552..759595 (+) 1044 WP_142998412.1 phenylalanine--tRNA ligase subunit alpha -
  GE021_RS03795 (GE021_003795) pheT 760310..762715 (+) 2406 WP_125073790.1 phenylalanine--tRNA ligase subunit beta -
  GE021_RS11240 - 762792..763077 (-) 286 Protein_717 integrase core domain-containing protein -
  GE021_RS03805 (GE021_003805) - 763077..763250 (+) 174 Protein_718 IS3 family transposase -

Sequence

Protein


Download         Length: 288 a.a.        Molecular weight: 31717.78 Da        Isoelectric Point: 10.0848

>NTDB_id=447273 GE021_RS03785 WP_125073792.1 757403..758269(+) (endA) [Streptococcus canis strain HL_77_1]
MLTKKKRTRALNSLLLILLVLGSSYLAKSDLIASNHPIKQFYQTLVGEKKESSPTNNNLQADVPTEALAASVLTHSIKEQ
LGADIQWNGAGAFIINQNRTDLNAAVASLPYANNETKWVQGKKVPTRANALLDKSTRQYRDRSQLDKGYRSFKPAGWHQL
YPLKGSYDHAVDRGHLLGYALIGGLKGFDASTSNPNNIATQLSWANQADKSYATGQNYYEGLVRRALDKGHRVRYRVTLL
YDGDNLLASGSHLEAKSADGSLTFNVFVPNVQPGLTVDYRTGQITINP

Nucleotide


Download         Length: 867 bp        

>NTDB_id=447273 GE021_RS03785 WP_125073792.1 757403..758269(+) (endA) [Streptococcus canis strain HL_77_1]
ATGTTAACAAAGAAAAAACGAACAAGAGCCCTTAATTCCTTGCTATTGATTTTATTAGTTTTGGGATCGAGTTACCTTGC
TAAAAGCGATTTAATTGCCAGTAATCACCCTATCAAGCAATTTTATCAAACCCTTGTTGGGGAGAAGAAGGAGTCATCAC
CCACAAATAATAACTTGCAGGCTGATGTTCCCACAGAAGCTCTGGCAGCATCTGTATTAACTCATTCAATCAAAGAGCAG
CTAGGTGCTGATATTCAGTGGAATGGGGCTGGAGCCTTTATTATTAACCAGAATAGAACAGATTTGAATGCAGCGGTGGC
CAGTCTGCCTTATGCCAACAATGAAACCAAATGGGTGCAAGGGAAAAAGGTTCCCACCAGAGCCAATGCCTTACTTGATA
AGTCAACACGGCAATATCGAGACCGTTCGCAACTTGATAAAGGTTACCGTTCATTTAAGCCAGCAGGTTGGCACCAATTG
TATCCTTTAAAAGGAAGTTATGACCATGCGGTGGATAGAGGGCATTTGCTAGGCTATGCTTTAATTGGCGGGCTGAAAGG
TTTTGATGCCTCCACTAGTAATCCCAACAATATTGCTACTCAACTAAGCTGGGCCAATCAGGCGGATAAATCTTATGCAA
CAGGGCAAAATTACTATGAAGGCTTAGTACGCCGTGCTTTAGATAAGGGACATCGCGTCCGCTACCGTGTCACCCTGCTT
TATGATGGTGATAATCTACTAGCAAGCGGTAGCCATTTGGAGGCCAAATCAGCTGATGGCAGCTTGACTTTTAACGTGTT
TGTTCCAAATGTCCAACCAGGATTGACCGTTGATTATCGGACGGGACAGATAACCATTAATCCCTGA

Domains

Predicted by InterproScan.

DNA/RNA non-specific endonuclease (Endonuclease_NS)

(110-246)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A3P5XMH9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  endA Streptococcus pneumoniae Rx1

56.818

91.667

0.521
  endA Streptococcus pneumoniae D39

56.818

91.667

0.521
  endA Streptococcus pneumoniae R6

56.818

91.667

0.521
  endA Streptococcus pneumoniae TIGR4

56.818

91.667

0.521